Results 41 to 50 of about 7,622 (205)

RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella [PDF]

, 2018
Brucellaceae are stealthy pathogens with the ability to survive and replicate in the host in the context of a strong immune response. This capacity relies on several virulence factors that are able to modulate the immune system and in their structural ...
Altabe, Silvia Graciela, Casabuono, Adriana Cristina, Cassataro, Juliana, Couto, Alicia Susana, Czibener, Cecilia, Fulgenzi, Fabiana Rosa, Guaimas, Francisco Fernando, Pasquevich, Karina Alejandra, Spera, Juan Manuel, Ugalde, Juan Esteban, Valguarnera, Pablo Ezequiel   +10 more
core   +1 more source

Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression. [PDF]

, 2016
status ...
A. A. Roger Thompson, Alison J. Harris, Amy Lewis, Astuti, Bart Ghesquière, Baysal, Baysal, Benn, Brian G. Keevil, Burnichon, Cramer, David Sammut, Eleni Daniel, Fiona Murphy, Fossati, Hannah, Jha, John Newell-Price, Joseph A. Willson, Kasahara, Kate E. McDonald, Levene, McGovern, Mecklenburgh, Moira K. B. Whyte, Peter Carmeliet, Peyssonnaux, Pranvera Sadiku, Rebecca S. Dickinson, Robert Jones, Sarah R. Walmsley, Sun, Takeda, Tannahill, Tracie Plant, Walmsley, Walmsley   +36 more
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Preparation of Succinyl Neocarzinostatin [PDF]

Antimicrobial Agents and Chemotherapy, 1974
All amino groups in a proteinous antitumor antibiotic, neocarzinostatin, were reacted with succinic anhydride yielding bis- N -succinyl neocarzinostatin which retained biological activity in vitro against human cell lines and a bacterium.
openaire   +2 more sources

Quantitative succinyl-proteome profiling of Chinese hickory (Carya cathayensis) during the grafting process

BMC Plant Biology, 2019
Background Chinese hickory (Carya cathayensis) is a popular nut plant having high economic value. Grafting is applied to accelerate the transition from vegetative phase to reproductive phase.
Huwei Yuan, Juanjuan Chen, Ying Yang, Chenjia Shen, Dongbin Xu, Junfeng Wang, Daoliang Yan, Yi He, Bingsong Zheng   +8 more
doaj   +1 more source

First comprehensive analysis of lysine succinylation in paper mulberry (Broussonetia papyrifera)

BMC Genomics, 2021
Background Lysine succinylation is a naturally occurring post-translational modification (PTM) that is ubiquitous in organisms. Lysine succinylation plays important roles in regulating protein structure and function as well as cellular metabolism. Global
Yibo Dong, Ping Li, Ping Li, Chao Chen
doaj   +1 more source

Improving protein succinylation sites prediction using embeddings from protein language model

Scientific Reports, 2022
Protein succinylation is an important post-translational modification (PTM) responsible for many vital metabolic activities in cells, including cellular respiration, regulation, and repair.
Suresh Pokharel, Pawel Pratyush, Michael Heinzinger, Robert H. Newman, Dukka B. KC   +4 more
doaj   +1 more source

Stable isotopic labeling in proteomics [PDF]

, 2008
Labeling of proteins and peptides with stable heavy isotopes (deuterium, carbon-13, nitrogen-15, and oxygen-18) is widely used in quantitative proteomics.
Beynon, Blagoev, Borisov, Browder, Choe, Conrads, Craig, de Godoy, De Leenheer, Dean, Desiderio, Enoksson, Gerber, Gevaert, Gevaert, Gevaert, Gevaert, Gevaert, Gonzalez, Gronborg, Gruhler, Gygi, Hansen, Harsha, Hsu, Hsu, Hsu, Impens, Ji, Krijgsveld, Kuster, Kuster, Lange, Lanquar, Lopez-Otin, MacCoss, Mann, Mason, Mirzaei, Munchbach, Oda, Ong, Ong, Overall, Pan, Perkins, Pratt, Rivers, Ross, Schmidt, Schnolzer, Schulze, Scott, Selbach, Sethuraman, Staes, Staes, Tam, Van Damme, Van Hoof, Vande Walle, Wahlander, Wang, Washburn, Wiese, Wu, Zhang, Zhang, Zhang, Zhou   +69 more
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Succinyl-proteome profiling of Dendrobium officinale, an important traditional Chinese orchid herb, revealed involvement of succinylation in the glycolysis pathway

BMC Genomics, 2017
Background Lysine succinylation is a ubiquitous and important protein post-translational modification in various eukaryotic and prokaryotic cells. However, its functions in Dendrobium officinale, an important traditional Chinese orchid herb with high ...
Shangguo Feng, Kaili Jiao, Hong Guo, Mengyi Jiang, Juan Hao, Huizhong Wang, Chenjia Shen   +6 more
doaj   +1 more source

Is acetylation a metabolic rheostat that regulates skeletal muscle insulin action? [PDF]

, 2015
Skeletal muscle insulin resistance, which increases the risk for developing various metabolic diseases, including type 2 diabetes, is a common metabolic disorder in obesity and aging.
LaBarge, Samuel, Migdal, Christopher, Schenk, Simon   +2 more
core   +2 more sources

Extensive comparison of protein sequence-based bioinformatics applications for predicting lysine succinylation sites: a comparative review

Biotechnology & Biotechnological Equipment
Lysine succinylation is a post-translational modification that occurs when a succinyl group bonds with a lysine residue and changes the polarity of lysine from positive to negative, causing significant changes in the structure and functioning of proteins.
Hussam Alsharif
doaj   +1 more source