Results 41 to 50 of about 6,092 (196)

Comprehensive analysis of the lysine succinylome in fish oil-treated prostate cancer cells

Life Science Alliance, 2023
Through a global lysine succinylation analysis of prostate cancer cells treated with fish oil, a significant number of lysine succinylation sites have been identified and FO-dependent GOT2 succinylation status may have a potential to inhibit building ...
Yifan Jiang, Chao He, Haokai Ye, Qianhan Xu, Xiuyuan Chen, Ying Chen, Jianying Sun, Sonia Rocha, Mu Wang   +8 more
doaj   +1 more source

Preparation of Succinyl Neocarzinostatin [PDF]

Antimicrobial Agents and Chemotherapy, 1974
All amino groups in a proteinous antitumor antibiotic, neocarzinostatin, were reacted with succinic anhydride yielding bis- N -succinyl neocarzinostatin which retained biological activity in vitro against human cell lines and a bacterium.
openaire   +2 more sources

Succinylation and redox status in cancer cells

Frontiers in Oncology, 2022
Succinylation is a post-translational modification (PTM) event that associates metabolic reprogramming with various pathological disorders including cancers via transferring a succinyl group to a residue of the target protein in an enzymic or non-enzymic
Xiaofeng Dai, Yanyan Zhou, Fei Han, Jitian Li   +3 more
doaj   +1 more source

Tandem mass tag-based quantitative proteomic analysis identification of succinylation related proteins in pathogenesis of thoracic aortic aneurysm and aortic dissection [PDF]

PeerJ, 2023
Background Thoracic aortic aneurysm and dissection (TAAD) are devastating cardiovascular diseases with a high rate of disability and mortality. Lysine succinylation, a newly found post-translational modification, has been reported to play an important ...
Yu Zhang, Hongwei Zhang, Haiyue Wang, Chenhao Wang, Peng Yang, Chen Lu, Yu Liu, Zhenyuan Xu, Yi Xie, Jia Hu   +9 more
doaj   +2 more sources

Systematic identification and comparative analysis of lysine succinylation between the green and white parts of chimeric leaves of Ananas comosus var. bracteatus

BMC Genomics, 2020
Background Lysine succinylation, an important protein posttranslational modification (PTM), is widespread and conservative. The regulatory functions of succinylation in leaf color has been reported. The chimeric leaves of Ananas comosus var.
Meiqin Mao, Yanbin Xue, Yehua He, Xuzixing Zhou, Fatima Rafique, Hao Hu, Jiawen Liu, Lijun Feng, Wei Yang, Xi Li, Lingxia Sun, Zhuo Huang, Jun Ma   +12 more
doaj   +1 more source

Quantitative succinyl-proteome profiling of Chinese hickory (Carya cathayensis) during the grafting process

BMC Plant Biology, 2019
Background Chinese hickory (Carya cathayensis) is a popular nut plant having high economic value. Grafting is applied to accelerate the transition from vegetative phase to reproductive phase.
Huwei Yuan, Juanjuan Chen, Ying Yang, Chenjia Shen, Dongbin Xu, Junfeng Wang, Daoliang Yan, Yi He, Bingsong Zheng   +8 more
doaj   +1 more source

Lysine succinylation precisely controls normal erythropoiesis

Haematologica
Lysine succinylation (Ksu) has recently emerged as a protein modification that regulates diverse functions in various biological processes. However, the systemically and precise role of lysine succinylation in erythropoiesis remains to be fully ...
Bin Hu, Han Gong, Ling Nie, Ji Zhang, Yanan Li, Dandan Liu, Huifang Zhang, Haihang Zhang, Lu Han, Chaoying Yang, Maohua Li, Wenwen Xu, Yukio Nakamura, Lihong Shi, Mao Ye, Christopher D. Hillyer, Narla Mohandas, Long Liang, Yue Sheng, Jing Liu   +19 more
doaj   +1 more source

Protein succinylation: regulating metabolism and beyond

Frontiers in Nutrition
Modifications of protein post-translation are critical modulatory processes, which alters target protein biological activity，function and/or location, even involved in pathogenesis of some diseases. So far, there are at least 16 types of post-translation
Xiaoli Hou, Yiqiu Chen, Xiao Li, Xianliang Gu, Weixia Dong, Jie Shi, Shaoping Ji, Shaoping Ji   +7 more
doaj   +1 more source

First comprehensive analysis of lysine succinylation in paper mulberry (Broussonetia papyrifera)

BMC Genomics, 2021
Background Lysine succinylation is a naturally occurring post-translational modification (PTM) that is ubiquitous in organisms. Lysine succinylation plays important roles in regulating protein structure and function as well as cellular metabolism. Global
Yibo Dong, Ping Li, Ping Li, Chao Chen
doaj   +1 more source

The involvement of high succinylation modification in the development of prostate cancer

Frontiers in Oncology, 2022
ObjectiveSuccinylation modification of the lysine site plays an important role in tumorigenesis and development, but it is rarely reported in prostate cancer (PCa), so this study aims to elucidate its expression in and clinical correlation with PCa ...
Zhenyang Zhang, Zhenyang Zhang, Yanru Chen, Yanru Chen, Lingyu Fang, Lingyu Fang, Jiang Zhao, Shishan Deng, Shishan Deng   +8 more
doaj   +1 more source