Molecular & Cellular Proteomics, 2019 Protein modification by lysine succinylation is a newly identified post-translational modification (PTM) of lysine residues and plays an important role in diverse physiological functions, although their associated biological characteristics are still largely unknown.
Zujie Yao +7 more
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Molecular & Cellular Proteomics, 2019 Lysine acetylation and succinylation are post-translational modifications of proteins that have been shown to play roles in plants response to pathogen infection. Phytoplasma infection can directly alter multiple metabolic processes in the deciduous plant Paulownia and lead to Paulownia witches' broom (PaWB) disease, the major cause of Paulownia ...
Yabing Cao +3 more
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SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer [PDF]
, 2018 Peroxisomes account for ~35% of total H2O2 generation in mammalian tissues. Peroxisomal ACOX1 (acyl-CoA oxidase 1) is the first and rate-limiting enzyme in fatty acid β-oxidation and a major producer of H2O2 ACOX1 dysfunction is linked to peroxisomal ...
Chen, Lei‐Lei +22 more
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Construction and Expression of Fc-FGF21 by Different Expression Systems and Comparison of Their Similarity and Difference with Efruxifermin by In Vitro and In Vivo Studies. [PDF]
Non-alcoholic steatohepatitis (NASH) is a potential serious disease, which almost has no available medicine for effective treatment today. Efruxifermin is a bivalent Fc-FGF21 candidate drug developed by Akero Therapeutics that has shown promising results
Feng, Hui +10 more
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, 2019 Three mass spectrometry examples of the succinylpeptides (Figure S1); Western blotting analysis with GAPDH antibody and succinyllysine antibody (Figure S2); GO-based enrichment analysis (Figure S3); Domain enrichment analysis of the succinylproteins (Figure S4). (DOC 9793 kb)
Wang, Guangyuan +4 more
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, 2016 The detailed description of the experiment methods, including rat model establishment, mass spectrometric analysis procedures and parameters, bioinformatics analysis softwares, websites. (DOCX 18 kb)
Cheng, Yang +4 more
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Protein Succinylation and Malonylation as Potential Biomarkers in Schizophrenia. [PDF]
J Pers Med, 2022 Smith BJ +6 more
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195 Comprehensive succinylome profiling reveals the pivotal role of lysine succinylation in energy metabolism and quorum sensing of Staphylococcus epidermidis [PDF]
Journal of Investigative Dermatology, 2021 Y. Zhao, R. Qi, H. Chen, X. Gao
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SIRT1 in the brain—connections with aging-associated disorders and lifespan [PDF]
, 2015 Fanny Ng
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Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.). [PDF]
BMC Plant Biol, 2022 Zhang B, Chen Z, Sun Q, Liu J.
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