Results 81 to 90 of about 423 (139)

LasB and CbpD Virulence Factors of Pseudomonas aeruginosa Carry Multiple Post-Translational Modifications on Their Lysine Residues

, 2019
Pseudomonas aeruginosa is a multi-drug resistant human pathogen largely involved in nosocomial infections. Today, effective antibacterial agents are lacking.
Charlotte Gaviard (5317526), Pascal Cosette (375609), Thierry Jouenne (200627), Julie Hardouin (635990)   +3 more
core   +2 more sources

Global Profiling of Protein Lysine Malonylation in Escherichia coli Reveals Its Role in Energy Metabolism

, 2016
Protein lysine malonylation is a recently identified post-translational modification (PTM), which is evolutionarily conserved from bacteria to mammals. Although analysis of lysine malonylome in mammalians suggested that this modification was related to ...
Yingming Zhao (194005), Litong Nie (2801737), Jun Zhu (84054), Ming Chen (115604), Lili Qian (1743571), Sheng-ce Tao (123957), Linhui Zhai (696754), Minjia Tan (629800), Ping Liu (156158), Zhongyi Cheng (194003)   +9 more
core   +1 more source

Additional file 2: of Quantitative succinylome analysis in the liver of non-alcoholic fatty liver disease rat model

, 2016
The detailed description of the experiment methods, including rat model establishment, mass spectrometric analysis procedures and parameters, bioinformatics analysis softwares, websites. (DOCX 18 kb)
Cheng, Yang, Tianlu Hou, Ping, Jian, Gaofeng Chen, Jianjie Chen   +4 more
openaire   +1 more source

Novel high-resolution ion mobility mass spectrometry for site-specific quantification of the sirtuin-5 regulated kidney succinylome

Journal of Proteomics
Abstract Protein post-translational modifications (PTMs) dynamically regulate essential biological and cellular processes. Lysine succinylation changes the amino acid charge, potentially affecting protein structures and functions, and dysregulation of protein succinylation may lead to metabolic disorders.
Birgit Schilling, Leonard Rorrer, Lauren Royer, Anne Silva-Barbosa, Katherine Pfister, Eric Goetzman, Sunder Sims-Lucas, Daniel DeBord, Joanna Bons   +8 more
openaire   +3 more sources

Acox2 deficiency induces cardiac dysfunction via cross-organ metabolic reprogramming in mice

Background Secondary cardiomyopathies are a major cause of heart failure (HF) with diverse etiologies and high mortality rates. For example, over 50% of patients with end-stage liver disease develop cardiac dysfunction, clinically ...
Cancan Yao, Boxuan Wu, Muling Zeng, Yan Chen, Zhouping Lu, Eudald Casals, Xiangyu Zhou, Feifei Wang, Yuan Zhang, Ke Cai   +9 more
core   +1 more source

MassIVE MSV000086971 - Succinylome-controlled antibiotic resistance in MRSA - Succinylome

, 2021
Geremy Clair ; James P. O'Gara
core   +1 more source

Lysine Succinylation Contributes to Aflatoxin Production and Pathogenicity in Aspergillus flavus

, 2018
Aspergillus flavus (A. flavus) is a ubiquitous saprophytic and pathogenic fungus that produces the aflatoxin carcinogen, and A. flavus can have tremendous economic and health impacts worldwide.
Nie, Xinyi, Li, Yu, Wang, Shihua, Yue, Yuewei, Yang, Mingkun, Ge, Feng, Ren, Silin, Guo, Xiaodong, Zhang, Jia, Zhang, Feng   +9 more
core   +1 more source

L'Effet " Modifications Post-Traductionnelles" : petits groupements chimiques, grandes conséquences? Caractérisation de protéines modifiées chez Pseudomonas aeruginosa PA14 par analyse protéomique.

, 2018
Pseudomonas aeruginosa PA14 is a multi-drug resistant human pathogen largely involved in nosocomial infections. Unfortunately, today, effective antibacterial agents lacked.
Gaviard, Charlotte
core  

"Post-translational modifications" effect : small chemical groups, influencial consequences? Characterization of modified proteins in Pseudomonas aeruginosa PA14 by proteomic analysis.

, 2018
Pseudomonas aeruginosa PA14 est une bactérie pathogène très résistante aux antibiotiques et impliquée dans de nombreuses infections nosocomiales. Toutefois, la disponibilité d'agents antibactériens efficaces contre cette bactérie manque cruellement à ce ...
Gaviard, Charlotte
core  

Succinylation modification provides new insights for the treatment of immunocompromised individuals with drug-resistant Aspergillus fumigatus infection. [PDF]

Front Immunol, 2023
Chen X, Lei W, Meng H, Jiang Y, Zhang S, Chen H, Du M, Xue X.   +7 more
europepmc   +1 more source