Results 71 to 80 of about 587 (147)

Succinylome Profiling the Function and Distribution of Lysine Succinylation in Saccharopolyspora erythraea

Applied Biochemistry and Biotechnology
Abstract As a novel protein post-translational modification, lysine succinylation is widely involved in metabolism regulation. To describe succinylated lysine's physiological functions and distribution patterns in Saccharopolyspora erythraea, a large and global protein succinylome was identified in a hypersuccinylated strain E3ΔsucC, using high-
Xiang Ke, Xing Jiang, Muhammad Hammad Hussain, Xiwei tian, Ju Chu   +4 more
openaire   +2 more sources

Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency [PDF]

, 2017
Acyl-CoA dehydrogenase 9 (ACAD9) is an assembly factor for mitochondrial respiratory chain Complex I (CI), and ACAD9 mutations are recognized as a frequent cause of CI deficiency.
Alharbi, Hana, Goetzman, Eric S., Haack, Tobias, Haberberger, Birgit, Häberle, Johannes, Karunanidhi, Anuradha, Kim, Jung-Ja, Mohsen, Al-Walid, Munnich, Arnold, Nicholls, Robert D., Prabhu, Dolly, Prochownik, Edward V., Prokisch, Holger, Rötig, Agnes, Schiff, Manuel, Taylor, Robert W., Uppala, Radha, Vockley, Jerry, Wang, Yudong, Xia, Chuanwu, Zhang, Yuxun   +20 more
core  

The Acyl-Proteome of Syntrophus aciditrophicus Reveals Metabolic Relationships in Benzoate Degradation. [PDF]

, 2022
Syntrophus aciditrophicus is a model syntrophic bacterium that degrades fatty and aromatic acids into acetate, CO2, formate, and H2 that are utilized by methanogens and other hydrogen-consuming microbes.
Fu, Janine, Gunsalus, Robert, James, Kimberly, Loo, Joseph, McInerney, Michael, Mouttaki, Housna, Muroski, John, Nguyen, Hong, Ogorzalek Loo, Rachel, Wofford, Neil   +9 more
core   +1 more source

Discovery and Identification of Serum Succinyl‐Proteome for Postmenopausal Women with Osteoporosis and Osteopenia

Orthopaedic Surgery, Volume 11, Issue 5, Page 784-793, October 2019., 2019
Objective For the purpose of providing evidence for the treatment of osteoporosis and osteopenia, this study retrospectively identified succinylation‐modified sites and proteins in postmenopausal women, and bioinformatics analysis were performed. Methods From January 2016 to June 2018, a total of 30 postmenopausal women aged from 55 to 70 years old ...
Li‐li Zhang, Chun‐wen Li, Kang Liu, Zhong Liu, Bo‐cheng Liang, Yi‐ran Yang, Xiao‐lin Shi   +6 more
wiley   +1 more source

Succinyl-proteome profiling of Dendrobium officinale, an important traditional Chinese orchid herb, revealed involvement of succinylation in the glycolysis pathway

BMC Genomics, 2017
Background Lysine succinylation is a ubiquitous and important protein post-translational modification in various eukaryotic and prokaryotic cells. However, its functions in Dendrobium officinale, an important traditional Chinese orchid herb with high ...
Shangguo Feng, Kaili Jiao, Hong Guo, Mengyi Jiang, Juan Hao, Huizhong Wang, Chenjia Shen   +6 more
doaj   +1 more source

Posttranslational regulation of plant membrane transporters

The Plant Journal, Volume 121, Issue 3, February 2025.
SUMMARY The movement of substances across biological membranes is often constrained by physical or energetic barriers, requiring the action of transporter proteins embedded within the lipidic bilayer. These transporters also provide finely tuned regulation of substrate fluxes, essential for maintaining cellular function under both normal and stress ...
María Niño‐González, Paula Duque
wiley   +1 more source

Mitochondrial epigenetics in aging and cardiovascular diseases [PDF]

, 2023
Mitochondria are cellular organelles which generate adenosine triphosphate (ATP) molecules for the maintenance of cellular energy through the oxidative phosphorylation. They also regulate a variety of cellular processes including apoptosis and metabolism.
Costantino, Sarah, Geiger, Martin, Gorica, Era, Mengozzi, Alessandro, Mohammed, Shafeeq Ahmed, Mongelli, Alessia, Paneni, Francesco, Ruschitzka, Frank   +7 more
core   +1 more source

Quantitative global proteome and lysine succinylome analyses provide insights into metabolic regulation and lymph node metastasis in gastric cancer [PDF]

Scientific Reports, 2017
AbstractWith the rapid development of high-throughput quantitative proteomic and transcriptomic approaches, the molecular mechanisms of cancers have been comprehensively explored. However, cancer is a multi-dimensional disease with sophisticated regulations, and few studies focus on the crosstalk among multiomics.
Yongxi Song, Jun Wang, Zhongyi Cheng, Peng Gao, Jingxu Sun, Xiaowan Chen, Chen Chen, Yunlong Wang, Zhenning Wang   +8 more
openaire   +2 more sources

Post‐translational modifications of proteins in cardiovascular diseases examined by proteomic approaches

The FEBS Journal, Volume 292, Issue 1, Page 28-46, January 2025.
Mass spectrometry (MS)‐based proteomics has proven to be a powerful method capable of mapping, localizing and quantifying post‐translational modifications (PTMs). PTMs play regulatory roles in protein functions/activities and the recognition of PTMs specific to cardiovascular pathologies is crucial for usage in clinics.
Miroslava Stastna
wiley   +1 more source

Involvement of the Vitamin D Receptor in Energy Metabolism Revealed by Profiling of Lysine Succinylome of White Adipose Tissue [PDF]

Scientific Reports, 2017
AbstractLysine succinylation, emerging as a novel post-translational modification, is closely related to the regulation of diverse biological processes, including many aspects of metabolism. Growing evidence suggests that low vitamin D status might exert an adverse impact on energy balance, adipogenesis and inflammation in white adipose tissue (WAT ...
Su, Han, Lou, Yan, Fu, Yu, Zhang, Yalin, Liu, Ning, Liu, Zuwang, Zhou, Yanyan, Kong, Juan   +7 more
openaire   +2 more sources