Results 81 to 90 of about 587 (147)

Organic acidurias: Major gaps, new challenges, and a yet unfulfilled promise [PDF]

, 2020
Organic acidurias (OADs) comprise a biochemically defined group of inherited metabolic diseases. Increasing awareness, reliable diagnostic work-up, newborn screening programs for some OADs, optimized neonatal and intensive care, and the development of ...
Baumgartner, M.R. (Matthias), Dimitrov, B. (Bianca), Kölker, S. (Stefan), Molema, F. (Femke), Mühlhausen, C. (Chris), Schmiesing, J. (Jessica), Schumann, A. (Anke), Williams, M. (Monique)   +7 more
core   +1 more source

Protein posttranslational modifications in metabolic diseases: basic concepts and targeted therapies

MedComm, Volume 5, Issue 10, October 2024.
Posttranslational modifications of proteins are involved in the development of metabolism‐related diseases such as diabetes mellitus, obesity, hyperlipidemia, and nonalcoholic fatty liver disease. PTMs mediates the development of diabetes mellitus by affecting insulin homeostasis, glucose metabolism, diabetic complications, gluconeogenesis, and β‐cell ...
Yunuo Yang, Jiaxuan Wu, Wenjun Zhou, Guang Ji, Yanqi Dang   +4 more
wiley   +1 more source

Quantitative succinyl-proteome profiling of Chinese hickory (Carya cathayensis) during the grafting process

BMC Plant Biology, 2019
Background Chinese hickory (Carya cathayensis) is a popular nut plant having high economic value. Grafting is applied to accelerate the transition from vegetative phase to reproductive phase.
Huwei Yuan, Juanjuan Chen, Ying Yang, Chenjia Shen, Dongbin Xu, Junfeng Wang, Daoliang Yan, Yi He, Bingsong Zheng   +8 more
doaj   +1 more source

Evidence for a negative correlation between human reactive enamine-imine intermediate deaminase a (Rida) activity and cell proliferation rate: Role of lysine succinylation of rida [PDF]

, 2021
none8noReactive intermediate deaminase (Rid) proteins are enzymes conserved in all domains of life. UK114, a mammalian member of RidA subfamily, has been firstly identified as a component of liver perchloric acid-soluble proteins (L-PSP).

core   +1 more source

Glycolanguage of the oral microbiota

Molecular Oral Microbiology, Volume 39, Issue 5, Page 291-320, October 2024.
Oral bacteria speak a sophisticated glycolanguage transmitted through versatile glycoinfrastructure, carbohydrate‐active enzymes, and lectins, which contributes decisively to their success in the oral habitat. Deciphering this glycolanguage opens new avenues for novel antibacterials to treat oral diseases. Abstract The oral cavity harbors a diverse and
Fiona F. Hager‐Mair, Susanne Bloch, Christina Schäffer   +2 more
wiley   +1 more source

SIRT5‐Mediated Desuccinylation of RAB7A Protects Against Cadmium‐Induced Alzheimer's Disease‐Like Pathology by Restoring Autophagic Flux

Advanced Science, Volume 11, Issue 30, August 14, 2024.
The underlying mechanism of autophagy on environmental cadmium‐induced Alzheimer's disease progression is vague. The findings indicated that SIRT5 desuccinylated and activated RAB7A at the K31 residue to rescue the cadmium‐provoked Alzheimer's disease progression by restoring the autophagic flux, and identified potential targets for the treatment of ...
Ping Deng, Tengfei Fan, Peng Gao, Yongchun Peng, Min Li, Jingdian Li, Mingke Qin, Rongrong Hao, Liting Wang, Min Li, Lei Zhang, Chunhai Chen, Mindi He, Yonghui Lu, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Shangcheng Xu, Zhou Zhou, Zhengping Yu, Huifeng Pi   +22 more
wiley   +1 more source

Increased susceptibility to Chrysanthemum Yellows phytoplasma infection in Atcals7ko plants is accompanied by enhanced expression of carbohydrate transporters [PDF]

, 2022
Main conclusion: Loss of CALS7 appears to confer increased susceptibility to phytoplasma infection in Arabidopsis, altering expression of genes involved in sugar metabolism and membrane transport.
Bernardini C., Buoso S., Levy A., Mian G., Musetti R., Santi S., Suh J. H., van Bel A. J. E., Vincent C., Wang Y.   +9 more
core   +1 more source

Arming the troops: Post-translational modification of extracellular bacterial proteins [PDF]

, 2020
Funder: The Evelyn TrustFunder: The Cystic Fibrosis TrustFunder: British Lung Foundation; FundRef: https://doi.org/10.13039/501100000351Protein secretion is almost universally employed by bacteria.
Forrest, Suzanne, Welch, Martin
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Barcelona conference on epigenetics and cancer: 50 years of histone acetylation [PDF]

, 2018
The Barcelona Conference on Epigenetics and Cancer (BCEC) was held in Barcelona, Spain, on October 1 and 2 , 2014. The meeting was co-organized by the Cancer Epigenetics and Biology Program (PEBC-IDIBELL) and B·Debate, an initiative of Biocat, with the ...
Ausió, Juan, Esteller, Manel, Pérez Salvia, Montserrat, Simó-Riudalbas, Laia   +3 more
core   +1 more source

Lysine succinylation precisely controls normal erythropoiesis

Haematologica
Lysine succinylation (Ksu) has recently emerged as a protein modification that regulates diverse functions in various biological processes. However, the systemically and precise role of lysine succinylation in erythropoiesis remains to be fully ...
Bin Hu, Han Gong, Ling Nie, Ji Zhang, Yanan Li, Dandan Liu, Huifang Zhang, Haihang Zhang, Lu Han, Chaoying Yang, Maohua Li, Wenwen Xu, Yukio Nakamura, Lihong Shi, Mao Ye, Christopher D. Hillyer, Narla Mohandas, Long Liang, Yue Sheng, Jing Liu   +19 more
doaj   +1 more source