Results 61 to 70 of about 941,649 (339)

Electrophysiological and molecular mechanisms of protection by iron sucrose against phosphine-induced cardiotoxicity: A time course study [PDF]

open access: yes, 2015
The present study was designed for determining the exact mechanism of cytotoxic action of aluminum phosphide (AlP) in the presence of iron sucrose as the proposed antidote.
Abdollahi, M.   +8 more
core   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Plastid redox state and sugars: Interactive regulators of nuclear-encoded photosynthetic gene expression [PDF]

open access: yes, 2001
Feedback regulation of photosynthesis by carbon metabolites has long been recognized, but the underlying cellular mechanisms that control this process remain unclear.
Dominy, P J   +3 more
core   +2 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Allatostatin-A neurons inhibit feeding behavior in adult Drosophila [PDF]

open access: yes, 2012
How the brain translates changes in internal metabolic state or perceived food quality into alterations in feeding behavior remains poorly understood.
Anderson, David J.   +2 more
core   +2 more sources

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Dietary chia seed (Salvia hispanica L.) rich in a-linolenic acid improves adiposity and normalises hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats [PDF]

open access: yes, 2009
The present study investigates the benefits of the dietary intake of chia seed (Salvia hispanica L.) rich in α-linolenic acid and fibre upon dyslipidaemia and insulin resistance (IR), induced by intake of a sucrose-rich (62.5 %) diet (SRD).
Chicco, Adriana Graciela   +4 more
core   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

INFLUENCE OF EXOGENOUS GIBBERELLIN AND ITS MIXTURE WITH SUCROSE ON THE FORMATION OF XYLEM INCREMENT OF SILVER BIRCH

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2019
We studied the effect of gibberellin on cambial activity towards the xylem formation in adult birch trees (Betula pendula Roth var. pendula, common birch). The injection of exogenous solutions was used as a methodological technique. To do this, “chambers”
Ludmila Novitskaya   +4 more
doaj   +1 more source

Sucrose Synthase [PDF]

open access: yesPlant Signaling & Behavior, 2007
SUCROSE SYNTHASE (SUS: EC 2.4.1.13), a key enzyme in plant sucrose catabolism, is uniquely able to mobilize sucrose into multiple pathways involved in metabolic, structural, and storage functions. Our research indicates that the biological function of SUS may extend beyond its catalytic activity.
Chalivendra C, Subbaiah   +3 more
openaire   +2 more sources

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