Results 71 to 80 of about 674,727 (353)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Upshot of syrup medicines on children′s oral health: An appraise

Journal of Indian Association of Public Health Dentistry, 2013
In 2002, the American Academy Of Pediatric Dentistry had developed the Caries-risk Assessment Tool (CAT) based on a set of physical, environmental and general health factors.
Garima Bhambhani, Vrinda Saxena, Ajay Bhambal, Sudhanshu Saxena, Shanthi G, Poonam Pandya, Sonal Kothari, Amit Singh Thakur   +7 more
doaj  

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Optimization of osmotic dehydration of tomatoes slices in salt and sucrose solutions using response surface methodology

Revue des Énergies Renouvelables, 2015
Response Surface Methodology (RSM) was used to investigate the effect of temperature solution, immersion time, salt concentration and sucrose concentration on the water loss and solid gain during osmotic dehydration of tomatoes slices.
A. Ferradji, F.S. Aït Chaouche, D. Belhachat, A. Malek   +3 more
doaj  

Understanding and manipulating sucrose phloem loading, unloading, metabolism, and signalling to enhance crop yield and food security.

Journal of Experimental Botany, 2014
Sucrose is produced in, and translocated from, photosynthetically active leaves (sources) to support non-photosynthetic tissues (sinks), such as developing seeds, fruits, and tubers.
D. Braun, Lu Wang, Y. Ruan
semanticscholar   +1 more source

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

Advanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe, Samantha Kaonis, Natalie Calahan, Neda Kabi, Soham Ghosh   +4 more
wiley   +1 more source

Synthetic exendin-4 disrupts responding to reward predictive incentive cues in male rats

Frontiers in Behavioral Neuroscience
Synthetic exendin-4 (EX4, exenatide), is a GLP-1 receptor agonist used clinically to treat glycemia in Type-2 diabetes mellitus. EX4 also promotes weight loss and alters food reward-seeking behaviors in part due to activation of GLP-1 receptors in the ...
Ken T. Wakabayashi, Ajay N. Baindur, Malte Feja, Mauricio Suarez, Mauricio Suarez, Karie Chen, Kimberly Bernosky-Smith, Caroline E. Bass, Caroline E. Bass   +8 more
doaj   +1 more source

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

THE BIOSYNTHESIS OF SUCROSE PHOSPHATE

Journal of Biological Chemistry, 1955
Blanco y ...
Leloir, Luis Federico, Cardini, Carlos E.   +1 more
openaire   +3 more sources

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source