Results 31 to 40 of about 1,739 (182)

Enantioselective Synthesis of Sulfinamidines via Asymmetric Rhodium–Catalyzed Imidation of Sulfenamides

ChemistryEurope, EarlyView.
In this work, a catalytic enantioselective imidation approach is presented for the preparation of enantioenriched sulfinamidines from sulfenamides, employing a chiral dirhodium(II) tetracarboxylate catalyst. This method enables the imidation of N,N‐bisalkyl sulfenamides in yields of up to 98% and enantiomeric ratios up to 98:2, with a catalyst loading ...
Michael Andresini, Théo Bissonnier, Juline Courtois, Pascal Retailleau, Benjamin Darses, Jean‐François Poisson, Tanguy Saget, Philippe Dauban   +7 more
wiley   +1 more source

Legionella pneumophila Carbonic Anhydrases: Underexplored Antibacterial Drug Targets

Pathogens, 2016
Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes which catalyze the hydration of carbon dioxide to bicarbonate and protons. Many pathogenic bacteria encode such enzymes belonging to the α-, β-, and/or γ-CA families.
Claudiu T. Supuran
doaj   +1 more source

Isosteviol – A new scaffold for the synthesis of carbonic anhydrase II inhibitors

Results in Chemistry
The diterpene isosteviol can easily be synthesized via hydrolysis from stevioside, a renewable resource adding particular utility to its potential for drug synthesis. Of late, there has been an increase in scientific studies focusing on inhibitors of the
Toni C. Denner, Niels V. Heise, René Csuk   +2 more
doaj   +1 more source

Potential Impact of Childhood Abuse on Quality of Life During Mood‐Stabilising Treatment in Individuals Living With Bipolar Disorder

Bipolar Disorders, Volume 28, Issue 2, March 2026.
ABSTRACT Background There is a lack of research examining whether childhood abuse affects the quality of life (QoL) of individuals living with bipolar disorder and its improvement over the course of treatment. Methods Data from the Clinical Health Outcomes Initiative in Comparative Effectiveness for Bipolar Disorder were used to explore the ...
Anna L. Wrobel, Olivia M. Dean, Mojtaba Lotfaliany, Michael Berk, Louisa G. Sylvia, Michael E. Thase, Thilo Deckersbach, Mauricio Tohen, Melvin G. McInnis, James H. Kocsis, Richard C. Shelton, Susan L. McElroy, Alyna Turner, Andrew A. Nierenberg   +13 more
wiley   +1 more source

Integrated In Silico, In Vivo, and Deep Learning Approaches in the Discovery of Novel Candidate Molecules for Aedes aegypti Control

Archives of Insect Biochemistry and Physiology, Volume 121, Issue 2, February 2026.
An integrated computational/experimental workflow was used to identify new candidate molecules for Aedes aegypti control. Docking of 1,070 chalcones against mJHBP, followed by in vivo assays, identified 4′‐chloro‐4‐methoxychalcone (2c) as the most active larvicide candidate.
Herbert Bezerra Leite, Filipe Alves Ribeiro Rodrigues, Luana Beatriz Rocha Silva, Vanessa Costa Santos, Rosalvo F. Oliveira Neto, Edilson B. Alencar Filho   +5 more
wiley   +1 more source

NH‐Sulfilimine Synthesis Catalyzed by Nonheme Iron(II) Complex

ChemistryEurope, Volume 4, Issue 2, February 2026.
Sulfilimines are emerging as valuable functional group in modern medicinal chemistry. Yet, their catalytic preparation is underexplored compared to sulfoximines. Here, the iron‐catalyzed synthesis of 14 examples of unprotected sulfilimines in good yields, under aerobic atmosphere and at room temperature, is described.
Léa Tesson, Jean‐Pierre Mahy, Frédéric Avenier   +2 more
wiley   +1 more source

Selective Wettability–Driven Evaporation‐Enhanced Redox Cycling for Robust and Ultrasensitive Detection of Viral Particles

Small Methods, Volume 10, Issue 4, 23 February 2026.
ABSTRACT Timely detection of viral infections, particularly in settings outside centralized laboratories, is essential for controlling outbreaks. Small electrochemical biosensors are appealing because they are fast, require microliter sample volumes, and can be integrated into portable devices.
Pouya Soltan Khamsi, Shubhada K Chothe, Suresh V Kuchipudi, Aida Ebrahimi   +3 more
wiley   +1 more source

Preparation and Antimicrobial Studies of Acyclic Sulfamates. [PDF]

Acta Chemica Scandinavica, 1999
A series of acyclic sulfamates have been prepared and tested for antimicrobial activity. Thus, the oxysulfonyl isocyanates, ROSO2NCO (1a, R = 4-methoxyphenyl; 1b, R = phenyl; 1c, R = 4-chlorophenyl and 1d, R = 2,2,2-trifluoroethyl) have been prepared in 76-91% yield from chlorosulfonyl isocyanate.
Hanna S. H. Gautun, Tom Bergan, Per H. J. Carlsen, Mia Helkearo, Harri Lönnberg, Shi-Ping Yan, Geng-Lin Wang, Xin-Kan Yao, Hong-Gen Wang, J. -P. Tuchagues, Mattias Ögren   +10 more
openaire   +2 more sources

Unusual Covalent Tethers for Precise Amino-Alcohol Syntheses: Ring Opening of Epoxides by Pendant Sulfamates and Sulfamides [PDF]

, 2023
Shyam Sathyamoorthi, Someshwar Nagamalla, Joel T. Mague   +2 more
openalex   +1 more source

Nutzung des kooperativen Energie‐ und Wasserstofftransfers für die direkte Aminierung von nicht aktivierten Alkanen

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Kooperativer EnT & HAT: neue Methode zur direkten C─N‐Kopplung von nicht aktivierten Alkanen. Metallfreie photokatalytische Aminierung. Verwendung von nicht aktivierten Alkanen. Neuartiger Reaktionsweg. Abstrakt Während in letzter Zeit wichtige Fortschritte bei der direkten Funktionalisierung von Alkanen durch photokatalytische Verfahren erzielt wurden,
Sai Teja Kolla, Àlex Díaz‐Jiménez, Sven Trienes, Ignacio Funes‐Ardoiz, Joanna Wencel‐Delord   +4 more
wiley   +1 more source