Results 81 to 90 of about 31,866 (306)
The FEBS Journal, EarlyView.Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana +4 more
wiley +1 more source
Oncology Letters, 2017 17β-estradiol (E2) can contribute to the progression of epithelial ovarian cancer (EOC). Although the majority of patients with EOC are postmenopausal woman, when de novo estrogen production in the ovary has ceased, ovarian cancer cells remain exposed to
F. Mungenast +9 more
semanticscholar +1 more source
Symbiotic Human Gut Bacteria with Variable Metabolic Priorities for Host Mucosal Glycans. [PDF]
, 2015 UnlabelledMany symbiotic gut bacteria possess the ability to degrade multiple polysaccharides, thereby providing nutritional advantages to their hosts.
German, J Bruce +5 more
core +2 more sources
The FEBS Journal, EarlyView.Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2008 The crude glucosinolates (GSs) were extracted from bolting stems of Chinese kale (Brassica alboglabra) and purified by a column packed with DEAE Sephadex A-25. The desulpho-glucosinolates were obtained after desulfurizing of GSs by sulfatase.
LA Gui-xiao +3 more
doaj +1 more source
JIMD Reports, 2019 Multiple sulfatase deficiency (MSD) is an ultra‐rare lysosomal storage disorder (LSD). Mutations in the SUMF1 gene encoding the formylglycine generating enzyme (FGE) result in an unstable FGE protein with reduced enzymatic activity, thereby affecting the
Lars Schlotawa +6 more
semanticscholar +1 more source
Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2 [PDF]
, 2013 Dehydroepiandrosterone sulfate (DHEAS) is a circulating steroid produced in the adrenal cortex, brain, and gonads. Whereas a series of investigations attest to neuroprotective effects of the steroid in the brain, surprisingly little is known about the ...
Adam, Jaroslav +50 more
core +2 more sources
Plant, Cell &Environment, EarlyView.ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source
Frontiers in Cell and Developmental BiologyIntroduction: Heparan sulfate (HS) in the vascular endothelial glycocalyx (eGC) is a critical regulator of blood vessel homeostasis. Trauma results in HS shedding from the eGC, but the impact of trauma on HS structural modifications that could influence ...
Robert P. Richter +12 more
doaj +1 more source
Antitumor activity of sulforaphane in mice model of skin cancer via blocking sulfatase‐2
Experimental Dermatology, 2018 Although there are many treatment options for skin cancer, the chemotherapeutic agents for skin cancer are linked with many adverse effects as well as the development of multidrug resistance.
A. Alyoussef, M. Taha
semanticscholar +1 more source