Results 151 to 160 of about 17,627 (184)

A highly regular fucan sulfate from the sea cucumber Stichopus horrens

Carbohydrate Research, 2018
A highly regular fucan sulfate SHFS was isolated from the sea cucumber Stichopus horrens by extraction of the body walls in the presence of papain followed by ion-exchange and gel permeation chromatography. SHFS had MW of about 140 kDa and contained fucose and sulfate in the molar ratio of about 1:1.
Nadezhda E, Ustyuzhanina, Maria I, Bilan, Andrey S, Dmitrenok, Elizaveta Yu, Borodina, Nikolay E, Nifantiev, Anatolii I, Usov   +5 more
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Molecular characterization and immunomodulatory activity of sulfated fucans from Agarum cribrosum

Carbohydrate Polymers, 2014
The sulfated-fucans, known as fucoidans, were isolated from Agarum cribrosum and fractionated using ion-exchange chromatography to determine their molecular characteristics and in vitro immunomodulatory activity. The crude and fractionated fucoidans (F1 and F2) consisted mostly of carbohydrates (52.4-56.0%), sulfates (12.7-23.0%) and uronic acid (14.1 ...
MyoungLae, Cho, Dong-Jin, Lee, Jin-Kyung, Kim, SangGuan, You   +3 more
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Polysaccharides From the Brown Seaweed Padina tetrastromatica: Characterization of a Sulfated Fucan

Carbohydrate Polymers, 2009
Sulfated fucans, the complex polysaccharides from brown seaweeds, possess various biological activities. To understand the structure activity relationship of sulfated fucans, we have investigated the structural features of one such polymer from Padina tetrastromatica using standard methods of carbohydrate structural analysis.
Bimalendu Ray, Sudipta Saha, Tuhin Ghosh
exaly   +2 more sources

Use of Sulfated Fucans as Anticoagulant and Antithrombotic Agents: Future Perspectives

Current Pharmaceutical Design, 2004
Sulfated alpha-L-fucans from brown algae (also known as fucoidan) have complex and heterogeneous structures but recent studies revealed the occurrence of ordered repeat units in the sulfated fucans from several species. Even in these cases, the presence of highly branched portions and the complex distributions of sulfate and acetyl groups highlight the
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A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity

Carbohydrate Polymers, 2021
Marine sulfated polysaccharides have aroused widespread concern for their various structures and bioactivities. Peroxide depolymerization is a common strategy in analysis of structures and structure-activity relationships of polysaccharides. However, confirming the depolymerization process and exact structures of the degradation products is still a ...
Xiaomei, Li, Shanni, Li, Jie, Liu, Lisha, Lin, Huifang, Sun, Wenjiao, Yang, Ying, Cai, Na, Gao, Lutan, Zhou, Hongbo, Qin, Ronghua, Yin, Jinhua, Zhao   +11 more
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Inhibition of complement activation by natural sulfated polysaccharides (fucans) from brown seaweed

Molecular Immunology, 1994
In the present study, we demonstrate that natural sulfated polysaccharides (fucans) isolated from brown seaweed are potent inhibitors of human complement activation. A fucan fraction of chromatographic molecular weight 22,600, termed BS8, was found to inhibit classical and alternative pathway activation in whole serum in a dose-dependent fashion. Fucan
C, Blondin, E, Fischer, C, Boisson-Vidal, M D, Kazatchkine, J, Jozefonvicz   +4 more
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Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava

International Journal of Biological Macromolecules, 2014
Water-soluble sulfated fucans isolated from Ecklonia cava were fractionated using an anion-exchange chromatography to investigate their molecular characteristics and immunomodulating activities. The crude fucoidan extract and purified fractions (EF1, EF2, and EF3) consisted mostly of different ratios of neutral sugars, proteins, sulfates, uronic acids,
Rong-An, Cao, YongJin, Lee, SangGuan, You   +2 more
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NMR‐based conformation and dynamics of a tetrasaccharide‐repeating sulfated fucan substituted by different counterions

Biopolymers, 2016
AbstractThe sulfated fucan from the sea urchin Lytechinus variegatus is composed of the repetitive sequence [‐3)‐α‐l‐Fucp‐4( )‐(1‐3)‐α‐l‐Fucp‐2,4‐di( )‐(1‐3)‐α‐l‐Fucp‐2( )‐(1‐3)‐α‐l‐Fucp‐2( )‐(1‐]n. Conformation (of rings and chains) and dynamics of this tetrasaccharide‐repeating sulfated fucan substituted by Na+, Ca2+, and Li+ as counterions have been
Paulo A G, Soares, Ismael N L, Queiroz, Gustavo R C, Santos, Paulo A S, Mourão, Vitor H, Pomin   +4 more
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Structural characterization of a new anticoagulant fucan sulfate from the brown seaweed Ecklonia kurome

Carbohydrate Research, 1991
Methylation analysis of a fucose-containing, sulfated polysaccharide (C-II), which was isolated from the brown seaweed Ecklonia kurome and has a potent anticoagulant activity, showed the presence of 3-O- and 3,4-O-disubstituted fucopyranosyl residues in addition to small proportions of nonreducing, terminal fucofuranosyl and fucopyranosyl groups, and 2,
T, Nishino, T, Nagumo, H, Kiyohara, H, Yamada   +3 more
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An anticoagulant fucan sulfate with hexasaccharide repeating units from the sea cucumber Holothuria albiventer

Carbohydrate Research, 2018
A fucan sulfate was isolated and purified from the sea cucumber Holothuria albiventer by papain enzymolysis, alkaline hydrolysis and ion-exchange chromatography. The water-soluble polysaccharide had high molecular weight and contained fucose and sulfate in a molar ratio of about 1:0.83.
Ying, Cai, Wenjiao, Yang, Ronghua, Yin, Lutan, Zhou, Zhongkun, Li, Mingyi, Wu, Jinhua, Zhao   +6 more
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