Phosphate starvation stops bacteria digesting algal fucan that sequesters carbon
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Structural Characterization and Anticoagulant Potential of <i>Colochirus quadrangularis</i> Fucosylated Glycosaminoglycan 5-12 Oligomers with Unusual Branches. [PDF]
Zhang X +13 more
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Sulfated fucans are important polysaccharides with diverse biological and biomedical activities. Carbohydrate-binding modules (CBMs) could serve as beneficial tools for the investigation of polysaccharides. Nevertheless, no sulfated fucan-binding CBM has been hitherto discovered.
Xuanwei, Mei +6 more
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Structure and anticoagulant activity of a sulfated fucan from the sea cucumber Acaudina leucoprocta
International Journal of Biological Macromolecules, 2020A sulfated fucan was extracted, purified, and characterized from Acaudina leucoprocta (a low value sea cucumber) to better understand and utilize this species. The structure of the sulfated fucan was elucidated using chemical and modern spectroscopic analyses including HPGPC, IR, AFM, GC-MS, and NMR, and its bioactivity was investigated.
Laijin Su, Yin Chen
exaly +3 more sources
A sulfated α-l-fucan from sea cucumber
Carbohydrate Research, 1994A purified sulfated alpha-L-fucan from the sea cucumber body wall was studied, before and after almost complete desulfation, using methylation analysis and NMR spectroscopy. NMR analysis indicates that 2,4-di-O-sulfo-L-fucopyranose and unsubstituted fucopyranose are present in equal proportions, and that 2-O-sulfo-L-fucopyranose is present in twice ...
A C, Ribeiro +3 more
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Relationship between Sulfate Groups and Biological Activities of Fucans
Thrombosis Research, 2000The anticoagulant and antiproliferative effects of low molecular weight fucans with different sulfate content were examined. The anticoagulant activity was determined by activated partial thromboplastin time and the antiproliferative one was achieved in vitro on CCL39 fibroblast cell line.
F, Haroun-Bouhedja +3 more
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Searching for Alternatives to Heparin Sulfated Fucans from Marine Invertebrates
Trends in Cardiovascular Medicine, 1999We describe a variety of sulfated polysaccharides with regular and well-defined structures which are useful tools for elucidating structure/biological function relationship. Several of these compounds have anticoagulant and antithrombotic activities.
P A, Mourão, M S, Pereira
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A comprehensive review of sulfated fucan from sea cucumber: Antecedent and prospect
Carbohydrate PolymersSulfated fucan from sea cucumber is mainly consists of L-fucose and sulfate groups. Recent studies have confirmed that the structure of sulfated fucan mainly consists of repeating units, typically tetrasaccharides. However, there is growing evidence indicating the presence of irregular domains with heterogeneous units that have not been extensively ...
Long Yu, Yaoguang Chang
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Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava
International Journal of Biological Macromolecules, 2014Water-soluble sulfated fucans isolated from Ecklonia cava were fractionated using an anion-exchange chromatography to investigate their molecular characteristics and immunomodulating activities. The crude fucoidan extract and purified fractions (EF1, EF2, and EF3) consisted mostly of different ratios of neutral sugars, proteins, sulfates, uronic acids,
Rong-An, Cao +2 more
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Molecular characterization and immunomodulatory activity of sulfated fucans from Agarum cribrosum
Carbohydrate Polymers, 2014The sulfated-fucans, known as fucoidans, were isolated from Agarum cribrosum and fractionated using ion-exchange chromatography to determine their molecular characteristics and in vitro immunomodulatory activity. The crude and fractionated fucoidans (F1 and F2) consisted mostly of carbohydrates (52.4-56.0%), sulfates (12.7-23.0%) and uronic acid (14.1 ...
MyoungLae, Cho +3 more
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