Results 151 to 160 of about 1,141 (196)

Phosphate starvation stops bacteria digesting algal fucan that sequesters carbon

open access: yes
Xu Y   +14 more
europepmc   +1 more source

Characterization of a sulfated fucan-specific carbohydrate-binding module: A promising tool for investigating sulfated fucans

Carbohydrate Polymers, 2022
Sulfated fucans are important polysaccharides with diverse biological and biomedical activities. Carbohydrate-binding modules (CBMs) could serve as beneficial tools for the investigation of polysaccharides. Nevertheless, no sulfated fucan-binding CBM has been hitherto discovered.
Xuanwei, Mei   +6 more
openaire   +2 more sources

Structure and anticoagulant activity of a sulfated fucan from the sea cucumber Acaudina leucoprocta

International Journal of Biological Macromolecules, 2020
A sulfated fucan was extracted, purified, and characterized from Acaudina leucoprocta (a low value sea cucumber) to better understand and utilize this species. The structure of the sulfated fucan was elucidated using chemical and modern spectroscopic analyses including HPGPC, IR, AFM, GC-MS, and NMR, and its bioactivity was investigated.
Laijin Su, Yin Chen
exaly   +3 more sources

A sulfated α-l-fucan from sea cucumber

Carbohydrate Research, 1994
A purified sulfated alpha-L-fucan from the sea cucumber body wall was studied, before and after almost complete desulfation, using methylation analysis and NMR spectroscopy. NMR analysis indicates that 2,4-di-O-sulfo-L-fucopyranose and unsubstituted fucopyranose are present in equal proportions, and that 2-O-sulfo-L-fucopyranose is present in twice ...
A C, Ribeiro   +3 more
openaire   +2 more sources

Relationship between Sulfate Groups and Biological Activities of Fucans

Thrombosis Research, 2000
The anticoagulant and antiproliferative effects of low molecular weight fucans with different sulfate content were examined. The anticoagulant activity was determined by activated partial thromboplastin time and the antiproliferative one was achieved in vitro on CCL39 fibroblast cell line.
F, Haroun-Bouhedja   +3 more
openaire   +2 more sources

Searching for Alternatives to Heparin Sulfated Fucans from Marine Invertebrates

Trends in Cardiovascular Medicine, 1999
We describe a variety of sulfated polysaccharides with regular and well-defined structures which are useful tools for elucidating structure/biological function relationship. Several of these compounds have anticoagulant and antithrombotic activities.
P A, Mourão, M S, Pereira
openaire   +2 more sources

A comprehensive review of sulfated fucan from sea cucumber: Antecedent and prospect

Carbohydrate Polymers
Sulfated fucan from sea cucumber is mainly consists of L-fucose and sulfate groups. Recent studies have confirmed that the structure of sulfated fucan mainly consists of repeating units, typically tetrasaccharides. However, there is growing evidence indicating the presence of irregular domains with heterogeneous units that have not been extensively ...
Long Yu, Yaoguang Chang
exaly   +3 more sources

Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava

International Journal of Biological Macromolecules, 2014
Water-soluble sulfated fucans isolated from Ecklonia cava were fractionated using an anion-exchange chromatography to investigate their molecular characteristics and immunomodulating activities. The crude fucoidan extract and purified fractions (EF1, EF2, and EF3) consisted mostly of different ratios of neutral sugars, proteins, sulfates, uronic acids,
Rong-An, Cao   +2 more
openaire   +2 more sources

Molecular characterization and immunomodulatory activity of sulfated fucans from Agarum cribrosum

Carbohydrate Polymers, 2014
The sulfated-fucans, known as fucoidans, were isolated from Agarum cribrosum and fractionated using ion-exchange chromatography to determine their molecular characteristics and in vitro immunomodulatory activity. The crude and fractionated fucoidans (F1 and F2) consisted mostly of carbohydrates (52.4-56.0%), sulfates (12.7-23.0%) and uronic acid (14.1 ...
MyoungLae, Cho   +3 more
openaire   +2 more sources

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