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The influence of sulfate content and molecular weight of a fucan sulfate from the brown seaweed Ecklonia kurome on its antithrombin activity

Thrombosis Research, 1991
The antithrombin effects of the sub-fractionated fucans with different molecular weights and sulfate contents, which were prepared from a fucan sulfate isolated from the brown seaweed Ecklonia kurome, were examined for their abilities to inhibit thrombin-fibrinogen reaction and amidolytic activity of thrombin, and to bind to fibrinogen.
T, Nishino, Y, Aizu, T, Nagumo
openaire   +2 more sources

Structural analysis of sulfated fucan from Saccharina japonica by electrospray ionization tandem mass spectrometry

Carbohydrate Research, 2013
Desulfation of a fucoidan from Saccharina japonica by treatment with DMSO-MeOH resulted in partial degradation of polymeric molecules by methanolysis giving rise to a mixture of neutral, monosulfated, and disulfated fucooligosaccharides in the form of methyl glycosides. These oligomeric fragments were characterized by ESI-MS and ESI-CID-MS/MS.
Weihua, Jin   +4 more
openaire   +2 more sources

Sulfated Fucan Could Serve as a Species Marker of Sea Cucumber With Endo-1,3-Fucanase as the Essential Tool

Carbohydrate Polymers, 2023
Changhu Xue   +2 more
exaly  

Zinc specifically stimulates the selective binding of a peptide analog of bindin to sulfated fucans.

Peptide research, 1992
A synthetic nonapeptide (Leu-Arg-His-Leu-Arg-His-His-Ser-Asn) derived from the sequence of the sea urchin sperm adhesive protein, bindin, has been shown to bind sulfated fucans in high ionic strength (seawater) conditions. The binding is enhanced by approximately 100-fold in the presence of zinc ions, and no other transition metal tested demonstrates ...
P L, DeAngelis, C G, Glabe
openaire   +1 more source

Discovery of a Sulfated Fucan-Specific Carbohydrate-Binding Module: The First Member of a New Carbohydrate-Binding Module Family

International Journal of Biological Macromolecules, 2023
Changhu Xue   +2 more
exaly  

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