Results 91 to 100 of about 2,318 (179)

Increased Sulfiredoxin Expression in Gastric Cancer Cells May Be a Molecular Target of the Anticancer Component Diallyl Trisulfide

open access: yesBioMed Research International, 2019
Sulfiredoxin (Srx) is a newly discovered antioxidant enzyme playing a role in the catalytic reduction of oxidative modifications. Srx is overexpressed in a variety of cancers. It may promote carcinogenesis as well as tumor progression.
Juan Wang   +4 more
semanticscholar   +1 more source

Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses of Cryptococcus neoformans

open access: yesmBio, 2016
The basidiomycetous fungus Cryptococcus neoformans has been known to be highly radiation resistant and has been found in fatal radioactive environments such as the damaged nuclear reactor at Chernobyl. To elucidate the mechanisms underlying the radiation
Kwang-Woo Jung   +5 more
doaj   +1 more source

Sulfiredoxin-1 Enhances Cardiac Progenitor Cell Survival against Oxidative Stress via the Upregulation of the ERK/NRF2 Signal Pathway

open access: yesFree Radical Biology & Medicine, 2018
Cardiac stem/progenitor cells (CPCs) have recently emerged as a potentially transformative regenerative medicine to repair the infarcted heart. However, the limited survival of donor cells is one of the major challenges for CPC therapy.
Xiuchun Li   +6 more
semanticscholar   +1 more source

Biosynthesis of Zinc Oxide Nanoparticles Using Garlic Peel Extract and Their Antibacterial Potential

open access: yesMicrobiology Research
Zinc oxide nanoparticles (ZnO NPs) have gathered interest because of their unique characteristics and potential applications. In the current work, ZnO NPs underwent an eco-friendly biosynthesis process using garlic peel extract.
Ali Abdelmoteleb   +6 more
doaj   +1 more source

Origins of Ultrasensitivity and Complex Signaling Dynamics of Cellular Hydrogen Peroxide and Peroxiredoxin

open access: yesAntioxidants
Hydrogen peroxide (H2O2) plays a crucial role in cell signaling in response to physiological and environmental perturbations. H2O2 can oxidize typical 2-Cys peroxiredoxin (PRX) first into a sulfenic acid, which resolves into a disulfide that can be ...
Shengnan Liu, Jingbo Pi, Qiang Zhang
doaj   +1 more source

Enzymology of Sulfiredoxine, a sulfinyl reductase : characterization of the catalytic mechanism

open access: yes, 2009
Les peroxyrédoxines à deux cystéines typiques (2-Cys Prx) sont impliquées dans la résistance des cellules au stress oxydant associé à H2O2, en réduisant H2O2 en H2O. En parallèle, ces enzymes participent à la transduction du signal dépendant de H2O2 en tant que second messager, via leur état rédox.
openaire   +2 more sources

Experimental workflows for the accurate identification of mitochondrial redox events. [PDF]

open access: yesRedox Biol
Hernansanz-Agustín P   +17 more
europepmc   +1 more source

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