Results 51 to 60 of about 13,197 (261)

A systems biology approach reveals major metabolic changes in the thermoacidophilic archaeon Sulfolobus solfataricus in response to the carbon source L-fucose versus D-glucose [PDF]

, 2016
Archaea are characterised by a complex metabolism with many unique enzymes that differ from their bacterial and eukaryotic counterparts. The thermoacidophilic archaeon Sulfolobus solfataricus is known for its metabolic versatility and is able to utilize ...
Albaum, S.P., Albers, S.V., Albersmeier, A., Brasen, C., Fafenrot, K., Hoffmann, L., Kalinowski, J., Kouril, T., Meyer, B., Muller, K.B., Neumann-Schaal, M., Pham, T., Schmidt-Hohagen, K., Schomburg, D., Shen, L., Siebers, B., Stark, H., Wolf, J., Wright, P.C.   +18 more
core   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

Angewandte Chemie, Volume 137, Issue 36, September 1, 2025.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar, Florian Leidner, Nivesh Kumar, Jared L. Hass, Peter Madzelan, Douglas R. Powell, Victor W. Day, Pierre Le Magueres, Joseph D. Ferrara, Lee M. Daniels, Akihito Yamano, Sho Ito, Wei Niu, Helmut Grubmüller, Mark A. Wilson, David B. Berkowitz   +15 more
wiley   +2 more sources

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity. [PDF]

, 2006
The archaeal/eukaryotic proliferating cell nuclear antigen (PCNA) toroidal clamp interacts with a host of DNA modifying enzymes, providing a stable anchorage and enhancing their respective processivities.
Andrew S. Doré, Antony W. Oliver, Brunger, Bunting, CCP4, Chang, Chapados, Dalrymple, DeLano, Dianova, Dionne, Dionne, Emsley, Friedrich-Heineken, Gulbis, Helt, Hingorani, Hosfield, Kelman, Kong, Kontopidis, Krishna, Krokan, Laurence H. Pearl, Leslie, Mairi L. Kilkenny, Matsumiya, Matsumoto, Murante, Murshudov, Oyama, Parker, Parrilla-Castellar, Pearl, Roberts, S. Mark Roe, Sakurai, Sarah A. Jones, Shamoo, Shen, Smirnova, Stephen D. Bell, Storoni, Tom, Toueille, Tsuchimoto, Venclovas, Volkmer, Wang   +48 more
core   +4 more sources

Bioleaching of Molybdenum by Two New Thermophilic Strains Isolated and Characterized [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
This study involves the isolation and characterization of a bacterial strain capable of bioleaching molybdenum ore. Bacterial growth was observed when rock sample was incubated in 9K at 70 ºC.
Mahshid Roshani, Seyed Abbas Shojaosadati, Seyed Jaber Safdari, Ebrahim Vasheghani-Farahani, Kazem Mirjalili, Zahra Manafi   +5 more
doaj  

The Dichotomy of the Poly(ADP-Ribose) Polymerase-Like Thermozyme from Sulfolobus solfataricus

Challenges, 2018
The first evidence of an ADP-ribosylating activity in Archaea was obtained in Sulfolobus solfataricus(strain MT-4) where a poly(ADP-ribose) polymerase (PARP)-like thermoprotein, defined with the acronymous PARPSso, was found.
Maria Rosaria Faraone Mennella
doaj   +1 more source

Thermal stability and aggregation of sulfolobus solfataricus b-glycosidase are dependent upon the N-e-methylation of specific lysyl residues: critical role of in vivo post-translational modifications. [PDF]

, 2004
Methylation in vivo is a post-translational modification observed in several organisms belonging to eucarya, bacteria, and archaea. Although important implications of this modification have been demonstrated in several eucaryotes, its biological role in ...
A. ANDOLFO, A. SCIRE, C. VACCARO, E. BERTOLI, F. FEBBRAIO, F. GENTILE, F. TANFANI, PUCCI, PIETRO, R. BRIANTE, R. N.U.C.C.I., S. FORMISANO   +10 more
core   +1 more source

Identification of Archaea species from hot spring water in Hammam AL-Allel at Mosul Governorate

مجلة مركز بحوث التقنيات الاحيائية, 2014
Isolate, Identify of some species belonging to Archaea from water of hot and sulphid springs in Hammam Al-Allel City/ Nenavah Governorate. Seventy five samples were collected from hot springs during 2012. The Archaea species were isolated using ordinary
Mohammed A . AL-Qatan, Basima A. Abdullah, Waad Mahmood Raoof   +2 more
doaj   +1 more source

Archaeal Enzymes and Applications in Industrial Biocatalysts [PDF]

, 2015
Archaeal enzymes are playing an important role in industrial biotechnology. Many representatives of organisms living in “extreme” conditions, the so-called Extremophiles, belong to the archaeal kingdom of life.
Littlechild, JA
core   +3 more sources

Hydroxyurea-Mediated Cytotoxicity Without Inhibition of Ribonucleotide Reductase

Cell Reports, 2016
In many organisms, hydroxyurea (HU) inhibits class I ribonucleotide reductase, leading to lowered cellular pools of deoxyribonucleoside triphosphates. The reduced levels for DNA precursors is believed to cause replication fork stalling. Upon treatment of
Li Phing Liew, Zun Yi Lim, Matan Cohen, Ziqing Kong, Lisette Marjavaara, Andrei Chabes, Stephen D. Bell   +6 more
doaj   +1 more source

Sessile Lifestyle Offers Protection against Copper Stress in Saccharolobus solfataricus

Microorganisms, 2023
Some archaea from the genus Sulfolobus are important for bioleaching of copper, where metal resistant microorganisms are required. Biofilm generation is one of the ways microorganisms cope with some stimuli in nature, including heavy metals. The response
Alejandra Recalde, Gabriela González-Madrid, José Acevedo-López, Carlos A. Jerez   +3 more
doaj   +1 more source