As one of the earliest developed antimicrobial classes, sulfonamides remain important therapeutic options for the empiric and definitive treatment of various infectious diseases.
Amber Giles+3 more
doaj +4 more sources
A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria [PDF]
Sulfonamide-degrading bacteria have been discovered in various environments, suggesting the presence of novel resistance mechanisms via drug inactivation. In this study, Microbacterium sp.
Dae-Wi Kim+4 more
doaj +4 more sources
Coumarin sulfonamide derivatives: An emerging class of therapeutic agents
Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues.
Irfan Ali+7 more
doaj +2 more sources
Aminoacyl sulfonamide assembly in SB-203208 biosynthesis
Sulfonamide is in many important drugs yet is rare in nature and little is known about the synthesis of sulfonamide containing antibiotics. Here, the authors report on a detailed analysis of the biosynthesis machineries of the aminoacyl sulfonamide ...
Zhijuan Hu+3 more
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Effect of sulfonamide pollution on the growth of manure management candidate Hermetia illucens.
Antibiotics are commonly used in livestock and poultry farming. Residual antibiotics in manure may lead to antibiotic pollution of soil, surface water, and groundwater through land application and run-off rainfall.
Qiao Gao+6 more
doaj +2 more sources
Residues of Tetracycline, Erythromycin, and Sulfonamides in Beef, Eggs, and Honey from Grocery Stores in Knoxville, Tennessee, USA: Failure of Cooking to Decrease Drug Concentrations [PDF]
This study evaluated the concentrations of tetracycline, erythromycin, and sulfonamide in beef, eggs, and honey products sold at grocery stores and whether standard cooking to 160 °F (71 °C) reduced the concentrations of antimicrobials spiked into the ...
Shamim Sarkar+4 more
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【Objective】With the rapid development of large-scale livestock and poultry breeding industry, the pollution of sulfonamide antibiotics in livestock and poultry manure is becoming more and more prominent.
Weida YU+6 more
doaj +1 more source
Presence of Tetracycline and Sulfonamide Resistance Genes in Salmonella spp.: Literature Review
Tetracyclines and sulfonamides are broad-spectrum antibacterial agents which have been used to treat bacterial infections for over half a century. The widespread use of tetracyclines and sulfonamides led to the emergence of resistance in a diverse group ...
Sabrina Lunara Santos Pavelquesi+5 more
semanticscholar +1 more source
Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete
Sulfonamides and sulfamates are a group of organosulfur compounds that contain the signature sulfamoyl structural motif. These compounds were initially only known as synthetic antibacterial drugs but were later also discovered as natural products.
T. Awakawa, Lena Barra, I. Abe
semanticscholar +1 more source
Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides
Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan+7 more
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