Results 1 to 10 of about 77,925 (335)

Sulfonamide Allergies [PDF]

open access: yesPharmacy, 2019
As one of the earliest developed antimicrobial classes, sulfonamides remain important therapeutic options for the empiric and definitive treatment of various infectious diseases.
Amber Giles   +3 more
doaj   +3 more sources

A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria [PDF]

open access: yesEnvironment International, 2019
Sulfonamide-degrading bacteria have been discovered in various environments, suggesting the presence of novel resistance mechanisms via drug inactivation. In this study, Microbacterium sp.
Dae-Wi Kim   +4 more
doaj   +3 more sources

Residues of Tetracycline, Erythromycin, and Sulfonamides in Beef, Eggs, and Honey from Grocery Stores in Knoxville, Tennessee, USA: Failure of Cooking to Decrease Drug Concentrations [PDF]

open access: yesVeterinary Sciences
This study evaluated the concentrations of tetracycline, erythromycin, and sulfonamide in beef, eggs, and honey products sold at grocery stores and whether standard cooking to 160 °F (71 °C) reduced the concentrations of antimicrobials spiked into the ...
Shamim Sarkar   +4 more
doaj   +2 more sources

Cycloauration of pyridyl sulphonamides [PDF]

open access: yesDalton Transactions, 2008
The pyridyl-2-alkylsulfonamides C₅H₄N(CH₂)nNHSO₂R (n = 1,2; R = Me, Ph or p-C₆H₄Me) and 8-(p-tosylamino)quinoline undergo facile cycloauration reactions with H[AuCl₄] in water, giving metallacyclic complexes coordinated through the pyridyl (or quinolyl ...
Henderson, William   +2 more
core   +6 more sources

Study on Migration and Transformation of Sulfonamide Antibiotics in Livestock Manure-Soil-Plant-Water Systems

open access: yesGuangdong nongye kexue, 2022
【Objective】With the rapid development of large-scale livestock and poultry breeding industry, the pollution of sulfonamide antibiotics in livestock and poultry manure is becoming more and more prominent.
Weida YU   +6 more
doaj   +1 more source

Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides

open access: yesApplied Sciences, 2021
Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan   +7 more
doaj   +1 more source

Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues

open access: yesJACS Au, 2023
Sulfonamides are one of the most important pharmacophores in medicinal chemistry and sulfonamide analogs have gained substantial interest in recent years. However, the protein interactions of sulfonamides and especially of their analogs are underexplored.
Patrick L. Purder   +9 more
openaire   +3 more sources

Coumarin sulfonamide derivatives: An emerging class of therapeutic agents

open access: yesHeterocyclic Communications, 2020
Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues.
Irfan Ali   +7 more
doaj   +1 more source

Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases

open access: yesBiomolecules, 2022
Most neurodegenerative diseases are multifactorial, and the discovery of several molecular mechanisms related to their pathogenesis is constantly advancing.
Thayssa Tavares da Silva Cunha   +7 more
doaj   +1 more source

Novel Coumarin 7-Carboxamide/Sulfonamide Derivatives as Potential Fungicidal Agents: Design, Synthesis, and Biological Evaluation

open access: yesMolecules, 2022
Coumarin compounds have a variety of biological activities such as anti-tumor, anti-coagulation, anti-HIV, anti-fungal, and insecticidal. Amide and sulfonamide compounds have been used as fungicides for half a century, and dozens of varieties have been ...
Shu-Guang Zhang   +3 more
doaj   +1 more source

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