Results 1 to 10 of about 77,925 (335)
As one of the earliest developed antimicrobial classes, sulfonamides remain important therapeutic options for the empiric and definitive treatment of various infectious diseases.
Amber Giles+3 more
doaj +3 more sources
A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria [PDF]
Sulfonamide-degrading bacteria have been discovered in various environments, suggesting the presence of novel resistance mechanisms via drug inactivation. In this study, Microbacterium sp.
Dae-Wi Kim+4 more
doaj +3 more sources
Residues of Tetracycline, Erythromycin, and Sulfonamides in Beef, Eggs, and Honey from Grocery Stores in Knoxville, Tennessee, USA: Failure of Cooking to Decrease Drug Concentrations [PDF]
This study evaluated the concentrations of tetracycline, erythromycin, and sulfonamide in beef, eggs, and honey products sold at grocery stores and whether standard cooking to 160 °F (71 °C) reduced the concentrations of antimicrobials spiked into the ...
Shamim Sarkar+4 more
doaj +2 more sources
Cycloauration of pyridyl sulphonamides [PDF]
The pyridyl-2-alkylsulfonamides C₅H₄N(CH₂)nNHSO₂R (n = 1,2; R = Me, Ph or p-C₆H₄Me) and 8-(p-tosylamino)quinoline undergo facile cycloauration reactions with H[AuCl₄] in water, giving metallacyclic complexes coordinated through the pyridyl (or quinolyl ...
Henderson, William+2 more
core +6 more sources
【Objective】With the rapid development of large-scale livestock and poultry breeding industry, the pollution of sulfonamide antibiotics in livestock and poultry manure is becoming more and more prominent.
Weida YU+6 more
doaj +1 more source
Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides
Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan+7 more
doaj +1 more source
Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues
Sulfonamides are one of the most important pharmacophores in medicinal chemistry and sulfonamide analogs have gained substantial interest in recent years. However, the protein interactions of sulfonamides and especially of their analogs are underexplored.
Patrick L. Purder+9 more
openaire +3 more sources
Coumarin sulfonamide derivatives: An emerging class of therapeutic agents
Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues.
Irfan Ali+7 more
doaj +1 more source
Most neurodegenerative diseases are multifactorial, and the discovery of several molecular mechanisms related to their pathogenesis is constantly advancing.
Thayssa Tavares da Silva Cunha+7 more
doaj +1 more source
Coumarin compounds have a variety of biological activities such as anti-tumor, anti-coagulation, anti-HIV, anti-fungal, and insecticidal. Amide and sulfonamide compounds have been used as fungicides for half a century, and dozens of varieties have been ...
Shu-Guang Zhang+3 more
doaj +1 more source