Sulfonamides and trimethoprim [PDF]
Expert Review of Anti-infective Therapy, 2009 Sulfonamides and trimethoprim are inexpensive and effective antibacterial drugs that have been used extensively. The use of sulfonamides for systemic use has, however, decreased dramatically for several years, mainly because of resistance development in pathogenic bacteria and allergic side effects. Also the clinical efficiency of trimethoprim has been
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Ecofriendly Synthesis in Aqueous Medium: An Expeditious Approach to New N,N-Diethyl Amide Bearing Benzenemethanesulfonamides [PDF]
, 2013 An highly expeditious synthetic approach for the synthesis of benzenemethanesulfonamides (1a-k) and their new corresponding N,N-diethyl substituted amido moieties (2a-k) has been achieved in aqueous medium at room tem-perature. The reaction condition was
Ajani, O. O. +3 more
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Medical Sciences Forum, 2022 Cancer is a disease that has spread widely throughout the world and requires the development of new anticancer drugs. Curing cancer is a complicated process as the drugs that are used target human cells and cells that have undergone genetic changes and ...
Beata Żołnowska +2 more
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Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]
, 1967 Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M. +35 more
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A Comparative Study on the Interaction of Sulfonamide and Nanosulfonamide with Human Serum Albumin
Journal of Chemistry, 2013 Binding parameters of the N-phenyl benzene sulfonyl hydrazide, sulfonamide, and nanosulfonamide interaction with human serum albumin were determined by calorimetry method.
G. Rezaei Behbehani +3 more
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Analytical Detection of Sulfonamides and Organophosphorus Insecticide Residues in Fish in Taiwan
Molecules, 2020 Exposure to residues of antibiotics (e.g., sulfonamides) and insecticides (e.g., organophosphorus insecticides) in aquacultured food can adversely affect humans and animals and thus affect public health globally.
Chung-Pei Chang +10 more
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Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom [PDF]
, 2009 Prevalence of three sulfonamide resistance genes, sul1, sul2 and sul3 and sulfachloropyridazine (SCP) resistance was determined in bacteria isolated from UK manured agricultural clay soils and slurry samples, over a two year period.
Boxall, Alistair B.A. +5 more
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Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance [PDF]
, 2004 Pneumocystis pneumonia (PCP) remains a major cause of illness and death in HIV-infected persons. Sulfa drugs, trimethoprim-sulfamethoxazole (TMP-SMX) and dapsone are mainstays of PCP treatment and prophylaxis.
Atzori, C +6 more
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Synthesis and Antibacterial Activity of N,N-Diethylamide Bearing Benzenesulfonamide Derivatives [PDF]
, 2013 Sulfonamides are known to represent a class of medicinally important compounds which are extensively used as antibacterial agents. Hence, a series of new N,N-diethyl amide bearing sulfonamides (2a-k) were synthesized via amidation of easily prepared ...
Ajani, Olayinka O. +4 more
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Point Mutations in the folP Gene Partly Explain Sulfonamide Resistance of Streptococcus mutans
International Journal of Microbiology, 2013 Cotrimoxazole inhibits dhfr and dhps and reportedly selects for drug resistance in pathogens. Here, Streptococcus mutans isolates were obtained from saliva of HIV/AIDS patients taking cotrimoxazole prophylaxis in Uganda.
W. Buwembo +4 more
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