Results 181 to 190 of about 32,232 (288)

Designing Cyclic Nitrogen‐Bridged Sulfonamides with Anti‐Cancer Activity

open access: yesChemMedChem, EarlyView.
Nitrogen bridgehead compounds, especially cyclic sulfonamides, are an abundant motif in bioactive compounds. simple methods for the synthesis of nitrogen bridgehead sulfonamides is developed and their activity against cancer cell lines is explored. The N‐bridgehead heterocyclic structure is an abundant motif in a multitude of natural products.
Benedikt W. Grau   +4 more
wiley   +1 more source

Few Steps, Big Impact: Recent Advances in the Streamlined Synthesis of Multiply Chiral Heterohelicenes with Tunable Optoelectronic Properties

open access: yesChemistry–Methods, EarlyView.
Heterohelicenes with multiple chiral axes have the potential to drive next‐generation technologies due to their unique structural and optoelectronic features. This review highlights innovative short‐step synthetic strategies for double and triple heterohelicenes, emphasizing their ease of preparation and valuable (chir)optical features, along with high
Mohamed S. H. Salem, Shinobu Takizawa
wiley   +1 more source

Mg Plating in Nonethereal Electrolyte Solutions: Fact or Misconception?

open access: yesChemSusChem, EarlyView.
An overview of Mg electrochemistry in both ethereal and nonethereal electrolyte systems was provided. Comprehensive reviewing on the electrochemical Mg plating/stripping activity reaffirms that only a limited range of solvents support reversible Mg plating/stripping.
Toshihiko Mandai
wiley   +1 more source

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity. [PDF]

open access: yesSci Rep
Ghoshal A   +26 more
europepmc   +1 more source

Modular, Tricomponent, and Concurrent One‐Pot Synthesis of Libraries of γ‐Keto Sulfones and γ‐Keto Phosphine Oxides using Brønsted Acidic Eutectic Mixtures

open access: yesChemSusChem, EarlyView.
This study presents a sustainable, metal‐free, one‐pot synthesis of γ‐keto sulfones and phosphine oxides using a ChCl/p‐TSA·H2O eutectic mixture. The method enables regioselective CC and CX bond formation under mild conditions, aligning with Green Chemistry Principles.
Marina Ramos‐Martín   +2 more
wiley   +1 more source

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