Results 81 to 90 of about 2,674,072 (303)

The efficacy of single pharmacist medication review among type II diabetic patients who take six chronic medications or more: a case–control study

Israel Journal of Health Policy Research, 2022
Background Pharmacist medication review has been implemented in many health organizations throughout the world in an attempt to alleviate the underlying risk of polypharmacy in elderly patients.
Danielle Harmatz, Shlomo Vinker, Talia Wagner, Tal Raveh, Eugene Merzon, Avivit Golan Cohen   +5 more
doaj   +1 more source

Diazoxide-Unresponsive Congenital Hyperinsulinism in Children With Dominant Mutations of the β-Cell Sulfonylurea Receptor SUR1

Diabetes, 2011
OBJECTIVE Congenital hyperinsulinemic hypoglycemia is a group of genetic disorders of insulin secretion most commonly associated with inactivating mutations of the β-cell ATP-sensitive K+ channel (KATP channel) genes ABCC8 (SUR1) and KCNJ11 (Kir6.2 ...
Courtney Macmullen, Qing Zhou, K. Snider, Paul H. Tewson, Susan A. Becker, A. R. Aziz, A. Ganguly, S. Shyng, C. Stanley   +8 more
semanticscholar   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

A Protective Role of Glibenclamide in Inflammation-Associated Injury

Mediators of Inflammation, 2017
Glibenclamide is the most widely used sulfonylurea drug for the treatment of type 2 diabetes mellitus (DM). Recent studies have suggested that glibenclamide reduced adverse neuroinflammation and improved behavioral outcomes following central nervous ...
Gensheng Zhang, Xiuhui Lin, Shufang Zhang, Huiqing Xiu, Chuli Pan, Wei Cui   +5 more
doaj   +1 more source

Posttraumatic brain edema: Pathophysiology, management, and current concept

Apollo Medicine, 2019
Post traumatic cerebral edema is a multiplex process. Mainly two types of cerebral edema occurred after traumatic brain injury-vasogenic edema and cytotoxic edema.
Subhas K Konar, Dhaval Shukla, Amit Agrawal   +2 more
doaj   +1 more source

Conserved Intramolecular Disulfide Bond Is Critical to Trafficking and Fate of ATP-binding Cassette (ABC) Transporters ABCB6 and Sulfonylurea Receptor 1 (SUR1)/ABCC8*

Journal of Biological Chemistry, 2011
The ATP-binding cassette (ABC) transporter ABCB6 is a mitochondrial porphyrin transporter that activates porphyrin biosynthesis. ABCB6 lacks a canonical mitochondrial targeting sequence but reportedly traffics to other cellular compartments such as the ...
Y. Fukuda, L. Aguilar-Bryan, M. Vaxillaire, A. Dechaume, Yao Wang, M. Dean, Karobi Moitra, J. Bryan, J. Schuetz   +8 more
semanticscholar   +1 more source

Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

, 2001
BM567, a sulfonylurea compound - whose crystal structure is here discussed - and terbogrel, are both thromboxane receptor antagonists and thromboxane synthase inhibitors.
Delarge, Jacques, Rolin, Stéphanie, Wouters, Johan; id_orcid, Michaux, Catherine; id_orcid, Masereel, Bernard, Dogné, Jean-Michel, Durant, François   +6 more
core   +1 more source

Glucagon-like peptide analogues for type 2 diabetes mellitus : systematic review and meta-analysis [PDF]

, 2010
Background Glucagon-like peptide (GLP-1) analogues are a new class of drugs used in the treatment of type 2 diabetes. They are given by injection, and regulate glucose levels by stimulating glucose-dependent insulin secretion and biosynthesis ...
Deepson S Shyangdan, Christine Clar, Pawana Sharma, Royle, Pamela L, Sharma Pawana, Royle Pamela L, Clar, Christine, Clar, C., Waugh, Norman R, Waugh Norman R, Pamela L Royle, Shyangdan Deepson S, Clar Christine, Waugh, Norman, Norman R Waugh, Sharma, Pawana, Shyangdan, D. (Deepson), Shyangdan, Deepson S, Royle, Pamela   +18 more
core   +1 more source

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source

Impact of Single Nucleotide Polymorphism rs1799854 ABCC8 on Glibenclamide Glycemic Control in Patients with Type 2 Diabetes [PDF]

Al-Anbar Medical Journal
Background: The incidence of type 2 diabetes mellitus (T2DM) in Iraq is rising continuously. Glibenclamide (GLB), which is a sulfonylurea member, is an important treatment for T2DM.
Ameer Mahdi, Mohammed Rasool, Hasan AlKutubi, Qasim Marzah   +3 more
doaj   +1 more source