Results 91 to 100 of about 25,287 (258)
Current potential health benefits of sulforaphane
EXCLI journal, 2016 EXCLI Journal; 15:Doc571; ISSN 1611 ...
Kim, Jae Kwang, Park, Sang Un
openaire +3 more sources
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Can sulforaphane prevent the onset or slow the progression of osteoarthritis? [PDF]
, 2016 Osteoarthritis (OA) is a degenerative joint disease characterised in part by destruction of articular cartilage. There are currently no disease-modifying drugs to treat OA, with joint replacement the only treatment offered to patients at end-stage ...
Burrage +20 more
core +1 more source
Sulforaphane Rescues Ethanol-Suppressed Angiogenesis through Oxidative and Endoplasmic Reticulum Stress in Chick Embryos [PDF]
, 2018 Our previous study showed that ethanol exposure inhibited embryonic angiogenesis mainly due to the excessive stimulation of reactive oxygen species (ROS) production.
Bao, Yongping +3 more
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Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention
Cancer Medicine, Volume 15, Issue 2, February 2026.Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa +4 more
wiley +1 more source
Microbial carcinogenic toxins and dietary anti-cancer protectants [PDF]
, 2017 Several toxins are known which account for the ability of some bacteria to initiate or promote carcinogenesis. These ideas are summarised and evidence is discussed for more specific mechanisms involving chymotrypsin and the bacterial chymotryptic enzyme ...
Darlington, L. Gail, Stone, Trevor W.
core +2 more sources
Growth temperature influences postharvest glucosinolate concentrations and hydrolysis product formation in first and second cuts of rocket salad [PDF]
, 2020 Rocket salad species (Diplotaxis tenuifolia and Eruca sativa; also known as E. vesicaria) are known for their high concentrations of health-related isothiocyanates, which are derived from secondary metabolites called glucosinolates.
Bell, Luke +2 more
core +1 more source
Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds
Molecules, 2014 Dietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of
Gina Rosalinda De Nicola +3 more
doaj +1 more source
Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
Neuroprotective Effect of Sulforaphane against Methylglyoxal Cytotoxicity [PDF]
Chemical Research in Toxicology, 2015 Glycation, an endogenous process that leads to the production of advanced glycation end products (AGEs), plays a role in the etiopathogenesis of different neurodegenerative diseases, such as Alzheimer's disease (AD). Methylglyoxal is the most potent precursor of AGEs, and high levels of methylglyoxal have been found in the cerebrospinal fluid of AD ...
ANGELONI, CRISTINA +5 more
openaire +2 more sources