Results 41 to 50 of about 29,600 (252)

Measuring Sulforaphane and Its Metabolites in Human Plasma: A High Throughput Method

open access: yesMolecules, 2020
(1) Background: There is increasing understanding of the potential health benefits of cruciferous vegetables. In particular sulforaphane (SFN), found in broccoli, and its metabolites sulforaphane-glutathione (SFN-GSH), sulforaphane-cysteine (SFN-Cys ...
Annie Langston-Cox   +5 more
doaj   +1 more source

Sulforaphane attenuates dextran sodium sulphate induced intestinal inflammation via IL-10/STAT3 signaling mediated macrophage phenotype switching

open access: yesFood Science and Human Wellness, 2022
Innate immunity, particularly macrophages, is critical for intestinal homeostasis. Sulforaphane, a dietary isothiocyanate from cruciferous vegetables, has been reported to protect against intestinal inflammation.
Yuyang Sun   +4 more
doaj   +1 more source

Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity

open access: yesMolecules, 2022
For decades, various plants have been studied as sources of biologically active compounds. Compounds with anticancer and antimicrobial properties are the most frequently desired.
Ł. Janczewski
semanticscholar   +1 more source

Sulforaphane Attenuates Neutrophil ROS Production, MPO Degranulation and Phagocytosis, but Does Not Affect NET Formation Ex Vivo and In Vitro

open access: yesInternational Journal of Molecular Sciences, 2023
Sulforaphane has several effects on the human body, including anti-inflammation, antioxidation, antimicrobial and anti-obesity effects. In this study, we examined the effect of sulforaphane on several neutrophil functions: reactive oxygen species (ROS ...
Shiori Wakasugi-Onogi   +5 more
semanticscholar   +1 more source

Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential

open access: yesCancers, 2021
Simple Summary As of the past decade, phytochemicals have become a major target of interest in cancer chemopreventive and chemotherapeutic research. Sulforaphane (SFN) is a metabolite of the phytochemical glucoraphanin, which is found in high abundance ...
Anna E Kaiser   +7 more
semanticscholar   +1 more source

Antileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditions. [PDF]

open access: yesPLoS ONE, 2014
Sulforaphane is a dietary isothiocyanate found in cruciferous vegetables showing antileukemic activity. With the purpose of extending the potential clinical impact of sulforaphane in the oncological field, we investigated the antileukemic effect of ...
Carmela Fimognari   +8 more
doaj   +1 more source

Factors Influencing Glucoraphanin and Sulforaphane Formation in Brassica Plants: A Review

open access: yesJournal of Integrative Agriculture, 2012
Sulforaphane is a type of sulfur-containing isothiocyanates hydrolyzed from glucosinolates by myrosinase found in Brassica plants. Sulforaphane is a naturally occurring inducer of phase II enzymes in human and animal bodies to detoxify cancer-causing ...
Zhen-xin GU, Qiang-hui GUO, Ying-juan GU
doaj   +1 more source

Research Progress on Sulforaphane in the Prevention and Treatment of Nervous System Diseases [PDF]

open access: yesShipin Kexue, 2023
Sulforaphane is a natural product with excellent antioxidant and anti-inflammatory effects, which is ubiquitous in plants of the Brassicaceae family. The pathogenesis of nervous system diseases is complex, but many nervous system diseases are related to ...
SONG Xiaoye, PANG Xinyi, LU Yingjian
doaj   +1 more source

Characterization of theThreshold for NAD(P)H:quinone Oxidoreductase Activity in Intact Sulforaphane-treated Pulmonary Arterial Endothelial Cells [PDF]

open access: yes, 2011
Treatment of bovine pulmonary arterial endothelial cells in culture with the phase II enzyme inducer sulforaphane (5 μM, 24 h; sulf-treated) increased cell-lysate NAD(P)H:quinone oxidoreductase (NQO1) activity by 5.7 ± 0.6 (mean ± SEM)-fold, but intact ...
Bongard, Robert D.   +5 more
core   +2 more sources

Effect of Storage Conditions and Cooking Methods on Chlorophyll, Glucosinolate, and Sulforaphane Content in Broccoli Florets

open access: yesHorticulturae, 2021
The effects of storage conditions and cooking methods on chlorophyll, glucosinolate (GSL), and sulforaphane content in broccoli florets were investigated in this study.
Junwei Wang   +8 more
doaj   +1 more source

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