Results 51 to 60 of about 29,600 (252)

Effect of stevia supplementation of kale juice spheres on their quality changes during refrigerated shelf life [PDF]

, 2018
Kale is a vegetable with high contents of health–promoting compounds although its consumption as a beverage is highly limited due to its bitter flavour. Nonetheless, the bitter flavour of Brassicas may be masked by sweetening.
Artés Calero, Francisco, Artés Hernández, Francisco de Asís, Collado Marín, Elena, Martínez Hernández, Ginés Benito, Venzke Klug, Tâmmila   +4 more
core   +2 more sources

Age-Related Mitochondrial Impairment and Renal Injury Is Ameliorated by Sulforaphane via Activation of Transcription Factor NRF2

Antioxidants, 2022
Age is one of the major risk factors for the development of chronic pathologies, including kidney diseases. Oxidative stress and mitochondrial dysfunction play a pathogenic role in aging kidney disease.
R. S. Mohammad, M. Lokhandwala, A. Banday   +2 more
semanticscholar   +1 more source

Protective Activity of Broccoli Sprout Juice in a Human Intestinal Cell Model of Gut Inflammation [PDF]

, 2016
Benefits to health from a high consumption of fruits and vegetables are well established and have been attributed to bioactive secondary metabolites present in edible plants.
Baima, Simona, Ferruzza, Simonetta, Giusti, Anna Maria, Maldini, Mariateresa, Mattivi, Fulvio, Moneta, Elisabetta, Morelli, Giorgio, Murgia, Chiara, Nardini, Mirella, Natella, Fausta, Ranaldi, Giulia, Rossi, Carlotta, Sambuy, Yula, Scaccini, Cristina, Trošt, Kajetan   +14 more
core   +3 more sources

Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane. [PDF]

PLoS ONE, 2012
Sulforaphane-induced activation of the transcription factor NF-E2 related factor 2 (Nrf2 or the gene Nfe2l2) and subsequent induction of the phase II antioxidant system has previously been shown to exert neuroprotective action in a transient model of ...
Michelle J Porritt, Helene C Andersson, Linda Hou, Åsa Nilsson, Marcela Pekna, Milos Pekny, Michael Nilsson   +6 more
doaj   +1 more source

Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan

Frontiers in Cell and Developmental Biology, 2021
Broccoli-derived isothiocyanate sulforaphane inhibits inflammation and cancer. Sulforaphane may support healthy aging, but the underlying detailed mechanisms are unclear. We used the C. elegans nematode model to address this question.
Huihui Ji, Zhimin Qi, Daniel Schrapel, Monika Le, Yiqiao Luo, Bin Yan, Jury Gladkich, Michael Schaefer, Li Liu, Ingrid Herr   +9 more
doaj   +1 more source

Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction

Journal of the Formosan Medical Association, 2017
Background/Purpose: Cancer stem cells (CSCs) are deemed as the driving force of tumorigenesis in oral squamous cell carcinomas (OSCCs). In this study, we investigated the chemotherapeutic effect of sulforaphane, a dietary component from broccoli sprouts,
Chia-Ming Liu, Chih-Yu Peng, Yi-Wen Liao, Ming-Yi Lu, Meng-Lun Tsai, Jung-Chun Yeh, Chuan-Hang Yu, Cheng-Chia Yu   +7 more
doaj   +1 more source

The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines.

PLoS ONE, 2021
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is an important transcription factor that plays a pivotal role in cellular defense against oxidative injury.
Su-Jin Moon, Jooyeon Jhun, Jaeyoon Ryu, Ji Ye Kwon, Se-Young Kim, KyoungAh Jung, Mi-La Cho, Jun-Ki Min   +7 more
doaj   +1 more source

Phytochemical Compounds and Protection from Cardiovascular Diseasesa. A State of the Art [PDF]

, 2015
Cardiovascular diseases represent a worldwide relevant socioeconomical problem. Cardiovascular disease prevention relies also on lifestyle changes, including dietary habits.
PAGLIARO, BENIAMINO ROSARIO, RUBATTU, Speranza Donatella, SANTOLAMAZZA, CATERINA, SIMONELLI, FRANCESCA   +3 more
core   +4 more sources

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis [PDF]

, 2017
Osteoarthritis (OA), affecting joints and bone, causes physical gait disability with huge socio-economic burden; treatment remains palliative. Roles for antioxidants in protecting against such chronic disorders have been examined previously. Sulforaphane
Ahmed Aljazzar, Alam, Andrea Pollard, Andrew A. Pitsillides, Behzad Javaheri, Bellido, Blandine Poulet, Boris Chan, Brewster, Carbone, Castañeda, Chambers, Chambers, Chiusaroli, Christiansen, Clarke, Conaghan, Custers, Davidson, Davidson, Doube, Duarte, Elaine Shervill, Foster, Glasson, Glasson, Goldring, Goldring, Haseeb, Hayami, Henrotin, Ho, Hochman, Isabel R. Orriss, Javaheri, Javaheri, Juge, Juhl, Karsdal, Kim, Li, Little, Lo, Mark Hopkinson, Mason, Miriam Piles, Mündermann, Pasold, Pastoureau, Pauli, Pearson, Peter D. Lee, Piles, Poulet, Poulet, Poulet, Poulet, Poulet, Pritzker, Radin, Roberto de Souza, Scheller, Schnitzer, Tat, Taylor, Thaler, Uchida, Valdes, Vincelette, Wang, Wu, Xiao, Yu-Mei Chang, Zakkar   +73 more
core   +3 more sources

Sulforaphane Suppresses the Nicotine-Induced Expression of the Matrix Metalloproteinase-9 via Inhibiting ROS-Mediated AP-1 and NF-κB Signaling in Human Gastric Cancer Cells

International Journal of Molecular Sciences, 2022
Sulforaphane, a natural phytochemical compound found in various cruciferous vegetables, has been discovered to present anti-cancer properties. Matrix metalloproteinase-9 (MMP-9) plays a crucial role in gastric cancer metastasis.
Shinan Li, P. N. Khoi, H. Yin, Dhiraj Kumar Sah, Nam‐Ho Kim, S. Lian, Y. Jung   +6 more
semanticscholar   +1 more source