Results 61 to 70 of about 14,451 (212)
Frontiers in Pharmacology, 2022 Background: Sulforaphane, which is found in cruciferous vegetables, has been reported to have anti-inflammatory, antioxidant, and antitumour activities.
Pei Du +19 more
doaj +1 more source
The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway [PDF]
, 2022 Huanhuan Sun +8 more
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Isothiocyanate from Broccoli, Sulforaphane, and Its Properties [PDF]
Journal of Medicinal Food, 2019 Sulforaphane is an isothiocyanate occurring in stored form as glucoraphanin in cruciferous vegetables such as cabbage, cauliflower, and kale, and at high levels in broccoli especially in broccoli sprouts. Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through mercapturic acid pathway,
Alena, Vanduchova +2 more
openaire +2 more sources
Environmental modulators of vascular physiology and inflammation
Experimental Physiology, EarlyView.Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne +3 more
wiley +1 more source
Sulforaphane Delays Intervertebral Disc Degeneration by Alleviating Endoplasmic Reticulum Stress in Nucleus Pulposus Cells via Activating Nrf-2/HO-1 [PDF]
, 2023 Xiao Lu +10 more
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Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Multi-targeted prevention of cancer by sulforaphane [PDF]
Cancer Letters, 2008 Isothiocyanates are found in cruciferous vegetables such as broccoli, Brussels sprouts, cauliflower, and cabbage. Epidemiologic studies suggest that cruciferous vegetable intake may lower overall cancer risk, including colon and prostate cancer. Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables and is especially high in broccoli ...
Clarke, John D +2 more
openaire +3 more sources
Biopolymers, Volume 117, Issue 1, January 2026.ABSTRACT The effect of the enzyme‐mediated poly(gallic acid) (PGAL) as a potential redox regulator or redox activity compound (RAC) on the morphology of human neuroblastoma SH‐SY5Y cells and its methionine synthase (MS) activities is contrasted to those for disrupting compounds (EDC).
Gabriela García‐Cerón +7 more
wiley +1 more source
Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds
Molecules, 2014 Dietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of
Gina Rosalinda De Nicola +3 more
doaj +1 more source