Results 61 to 70 of about 29,600 (252)

Potential of Sulforaphane as a Natural Immune System Enhancer: A Review

Molecules, 2021
Brassicaceae are an outstanding source of bioactive compounds such as ascorbic acid, polyphenols, essential minerals, isothiocyanates and their precursors, glucosinolates (GSL).
A. Mahn, Antonio Castillo
semanticscholar   +1 more source

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner [PDF]

, 2021
BACKGROUND: The isothiocyanate sulforaphane (SFN) has multiple protein targets in mammalian cells, affecting processes of fundamental importance for the maintenance of cellular homeostasis, among which are those regulated by the stress response ...
Ahn, Clarke, Cornblatt, Dibble, Dinkova-Kostova, Fang, Ferreira de Oliveira, Hawley, Iaconelli, Jeong, Kim, Kumar, Matsui, Matsui, Morales, Moreno-Gonzalo, Myzak, Nave, Nishioka, Rozengurt, Sawai, Saxton, Shawky, Shen, Torrente, Wiczk, Wu, Yang, Zhang, Zhang, Zhang, Zhang, Zhang   +32 more
core   +3 more sources

Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder

Molecular Autism, 2021
Background Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways.
A. Zimmerman, Kanwaljit Singh, S. Connors, Hua Liu, A. Panjwani, L. Lee, Eileen Diggins, Ann Foley, S. Melnyk, Indrapal N. Singh, S. James, R. Frye, J. Fahey   +12 more
semanticscholar   +1 more source

NFE2-Related transcription factor 2 coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland [PDF]

, 2018
Background: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide metabolism during thyroid hormone synthesis, the gland must also defend itself against excessive oxidation ...
Amendola, Elena, Bongiovanni, Massimo, Carrasco, Nancy, Chartoumpekis, Dionysios V, Habeos, Ioannis, Juvenal, Guillermo Juan, Kensler, Thomas W., Liao, Xiao-Hui, Ntalampyra, Eleni, Refetoff, Samuel, Renaud, Cédric O., Ris Stalpers, Carrie, Rossich, Luciano Esteban, Santisteban, Pilar, Somm, Emmanuel, Sykiotis, Gerasimos P., Thomasz, Lisa, Trougakos, Ioannis P, Yamamoto, Masayuki, Ziros, Panos G   +19 more
core   +1 more source

Biological mechanisms and clinical efficacy of sulforaphane for mental disorders

General Psychiatry, 2022
Current clinical management of major mental disorders, such as autism spectrum disorder, depression and schizophrenia, is less than optimal. Recent scientific advances have indicated that deficits in oxidative and inflammation systems are extensively ...
Wensi Zheng, Xiaolong Li, T. Zhang, Jijun Wang   +3 more
semanticscholar   +1 more source

Quantitative determination of sulforaphane from broccoli extract tablets and its role in the protection of acute liver injury induced by ethanol

浙江大学学报. 农业与生命科学版, 2013
Sulforaphane (SFN) is an isothiocyanate (ITC) which exists as a precursor of glucosinolate (GS) in various cruciferous vegetables especially in broccoli. Sulforaphane has been regarded as a potential of anti-cancer agent derived from diet, mostly because
LI Baolong, TIAN Sicong, TAN Jie, LI Bing, CHEN Jingyu, SHAN Yujuan   +5 more
doaj   +1 more source

Accumulation of Sulforaphane and Alliin in Human Prostate Tissue

Nutrients, 2022
Diets rich in cruciferous vegetables have been associated with a lower risk of incidence and progression of prostate cancer. Sulforaphane, an isothiocyanate derived from 4-methylsulphinylbutyl glucosinolate (glucoraphanin) that accumulates in certain of ...
Tracey L. Livingstone, S. Saha, Federico Bernuzzi, G. Savva, Perla Troncoso-Rey, M. Traka, R. Mills, R. Ball, R. Mithen   +8 more
semanticscholar   +1 more source

Sulforaphane improves cognitive function administered following traumatic brain injury. [PDF]

, 2009
Recent studies have shown that sulforaphane, a naturally occurring compound that is found in cruciferous vegetables, offers cellular protection in several models of brain injury.
Dash, Pramod K, Moore, Anthony N, Orsi, Sara A, Zhang, Min, Zhao, Jing   +4 more
core   +1 more source

The potential for dietary factors to prevent or treat osteoarthritis [PDF]

, 2014
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping, Cassidy, Aedín, Clark, Ian M., Davidson, Rose K., Donell, Simon T., Green, Jonathan A., Hirst-Jones, Kimberley L., Jupp, Orla, Macgregor, Alexander J.   +8 more
core   +1 more source