Results 71 to 80 of about 29,600 (252)

Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review

Cancers
Simple Summary Recent oncological research highlights the promising role of naturally derived compounds in cancer prevention and treatment. Sulforaphane (SFN), a phytochemical found in cruciferous vegetables, is a powerful chemosensitizer that increases ...
B. Sailo, Le Liu, Suravi Chauhan, Sosmitha Girisa, Mangala Hegde, Liping Liang, M. Alqahtani, Mohamed Abbas, Gautam Sethi, A. Kunnumakkara   +9 more
semanticscholar   +1 more source

Maximization of Sulforaphane Content in Broccoli Sprouts by Blanching

Foods, 2022
Broccoli sprouts are a recognized source of health-promoting compounds, such as glucosinolates, glucoraphanin, and sulforaphane (SFN). Maximization of SFN content can be achieved by technological processing.
A. Mahn, Carmen Elena Pérez, Víctor Zambrano, Herna Barrientos   +3 more
semanticscholar   +1 more source

Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma [PDF]

BMB Reports, 2012
Sulforaphane (1-isothiocyanato-4-(methylsulfinyl)-butane), belongingto a family of natural compounds that are abundant in broccoli,has received significant therapeutic interest in recent years.However, the molecular basis of its effects remains to ...
Jun Ho Park, Jong Won Kim, Chang-Min Lee, Yeong Dae Kim, Sung Woon Chung, In Duk Jung, Kyung Tae Noh, Jin Wook Park, Deok Rim Heo, Yong Kyoo Shin, Jong Keun Seo, Yeong-Min Park   +11 more
doaj   +1 more source

Targeting crosstalk between Nrf-2, NF-κB and androgen receptor signaling in prostate cancer [PDF]

, 2018
Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in the initiation, development and progression of prostate cancer (PCa).
Khurana, Namrata, Sikka, Suresh C
core   +2 more sources

Anti-Inflammatory Therapeutic Mechanisms of Isothiocyanates: Insights from Sulforaphane

Biomedicines
Isothiocyanates (ITCs) belong to a group of natural products that possess a highly reactive electrophilic −N=C=S functional group. They are stored in plants as precursor molecules, glucosinolates, which are processed by the tyrosinase enzyme upon plant ...
Solomon Habtemariam
semanticscholar   +1 more source

Bioavailability of Glucoraphanin and Sulforaphane From High-Glucoraphanin Broccoli [PDF]

, 2018
Scope: Broccoli accumulates 4-methylsulphinylbutyl glucosinolate (glucoraphanin) which is hydrolyzed to the isothiocyanate sulforaphane. Through the introgression of novel alleles of the Myb28 transcription factor from Brassica villosa, broccoli ...
Al Janobi, Aune, Clarke, Clarke, Cotton, Covault, Fuentes, Gasper, Gigolashvili, Juge, Kassahun, Liu, Liu, Luang-In, Mithen, Saha, Sonderby, Thomson, Traka, Tse, Vermeulen, Wu, Zhang   +22 more
core   +1 more source

Preharvest Methyl Jasmonate Treatment Increased Glucosinolate Biosynthesis, Sulforaphane Accumulation, and Antioxidant Activity of Broccoli

Antioxidants, 2022
Broccoli is becoming increasingly popular among consumers owing to its nutritional value and rich bioactive compounds, such glucosinolates (GSLs) and hydrolysis products, which are secondary metabolites for plant defense, cancer prevention, and higher ...
Junwei Wang, Shuxiang Mao, Mantian Liang, Wenxia Zhang, Fangzhen Chen, Ke Huang, Qiuyu Wu   +6 more
semanticscholar   +1 more source

D, L-Sulforaphane Loaded Fe3O4@ Gold Core Shell Nanoparticles: A Potential Sulforaphane Delivery System. [PDF]

PLoS ONE, 2016
A novel design of gold-coated iron oxide nanoparticles was fabricated as a potential delivery system to improve the efficiency and stability of d, l-sulforaphane as an anticancer drug.
Hamidreza Kheiri Manjili, Leila Ma'mani, Sharareh Tavaddod, Maedeh Mashhadikhan, Abbas Shafiee, Hossein Naderi-Manesh   +5 more
doaj   +1 more source

KEAP1 and done? Targeting the NRF2 pathway with sulforaphane:Targeting the NRF2 Pathway with Sulforaphane [PDF]

, 2017
Background: Since the re-discovery of sulforaphane in 1992 and the recognition of the bioactivity of this phytochemical, many studies have examined its mode of action in cells, animals and humans.
Dinkova-Kostova, Albena T., Fahey, Jed W., Kensler, Thomas W., Kostov, Rumen V.   +3 more
core   +2 more sources

Sulforaphane prevents diabetes‐induced hepatic ferroptosis by activating Nrf2 signaling axis

Biofactors
Recently, we characterized the ferroptotic phenotype in the liver of diabetic mice and revealed nuclear factor (erythroid‐derived‐2)‐related factor 2 (Nrf2) inactivation as an integral part of hepatic injury.
N. Savić, M. Markelic, A. Stancic, K. Veličković, I. Grigorov, M. Vucetic, V. Martinović, Andjelija Gudelj, V. Otasevic   +8 more
semanticscholar   +1 more source