Influence of Sulfoxide Group Placement on Polypeptide Conformational Stability. [PDF]
, 2019 The synthesis of a homologous series containing five new nonionic sulfoxide containing polypeptides was described. Sulfoxide groups bestowed water solubility for all homologues, which allowed their use as a model for study of helix-coil transitions in ...
Bahrun, Ehab +2 more
core
Modular polyoxometalate-layered double hydroxides as efficient heterogeneous sulfoxidation and epoxidation catalysts [PDF]
, 2018 Selective sulfoxidation of sulfides and epoxidation of olefins are two types of important organic reactions and the corresponding products of sulfoxides, sulfones and epoxides are widely used as raw materials in industrial processes.
Al-Maksoud +57 more
core +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Monitoring of Methionine Sulfoxide Content and Methionine Sulfoxide Reductase Activity [PDF]
, 2017 The sulfur-containing amino acid methionine (Met) plays critical roles in protein synthesis, methylation, and sulfur metabolism. Both in its free form and in the form of an amino acid residue, it can be oxidized to the R and S diastereomers of methionine sulfoxide (MetO).
Tarrago, Lionel +3 more
openaire +3 more sources
Pinacol as a new green reducing agent: molybdenum-catalyzed chemoselective reduction of sulfoxides and nitroaromatics [PDF]
, 2012 Pinacol is disclosed as a new chemoselective and environmentally benign reducing agent for sulfoxides and nitroaromatics assisted by readily available dichlorodioxomolybdenum(VI) complexes as catalysts.
Arnáiz García, Francisco Javier +6 more
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Versatile C(sp2)−C(sp3) ligand couplings of sulfoxides for the enantioselective synthesis of diarylalkanes [PDF]
, 2016 The reaction of chiral (hetero)aryl benzyl sulfoxides with Grignard reagents affords enantiomerically pure diarylalkanes in up to 98% yield and greater than 99.5% enantiomeric excess.
Aggarwal +72 more
core +2 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molybdenum-catalyzed enantioselective sulfoxidation controlled by a nonclassical hydrogen bond between coordinated chiral imidazolium-based dicarboxylate and peroxido ligands [PDF]
, 2018 Chiral alkyl aryl sulfoxides were obtained by molybdenum-catalyzed oxidation of alkyl aryl sulfides with hydrogen peroxide as oxidant in mild conditions with high yields and moderate enantioselectivities.
Carrasco Carrasco, Carlos Jesús +2 more
core
Green process for adipic acid synthesis: oxidation by hydrogen peroxide in water micromelusions using Benzalkonium Chloride C12-14 surfactant [PDF]
, 2012 Adipic acid was synthesized by the oxidation of cyclohexene using 30% hydrogen peroxide in a microemulsion in the presence of sodium tungstate as catalyst.
Cognet, Patrick +3 more
core +3 more sources