Results 61 to 70 of about 17,437 (312)

Dramatic Influence of Ionic Liquid and Ultrasound Irradiation on the Electrophilic Sulfinylation of Aromatic Compounds by Sulfinic Esters

Molecules, 2017
The sulfinylation reaction of aromatic and hetero-aromatic compounds with sulfinic esters as electrophiles has been investigated in different ionic liquids and by means of different Lewis acid salts in order to get moderate to good yields of asymmetrical
Ngoc-Lan Thi Nguyen, Hong-Thom Vo, Fritz Duus, Thi Xuan Thi Luu   +3 more
doaj   +1 more source

Dearomative di- and trifunctionalization of aryl sulfoxides via [5,5]-rearrangement

Nature Communications, 2022
In contrast with well-established dearomatization protocols such as the Birch reduction, sigmatropic rearrangement-based dearomatizations are a less-explored but potentially effective route to saturated compounds.
Mengjie Hu, Yanping Liu, Yuchen Liang, Taotao Dong, Lichun Kong, Ming Bao, Zhi-Xiang Wang, Bo Peng   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Photocatalytic formation of carbon–sulfur bonds

Beilstein Journal of Organic Chemistry, 2018
This review summarizes recent developments in photocatalyzed carbon–sulfur bond formation. General concepts, synthetic strategies and the substrate scope of reactions yielding thiols, disulfides, sulfoxides, sulfones and other organosulfur compounds are ...
Alexander Wimmer, Burkhard König
doaj   +1 more source

Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide

BMB Reports, 2009
Dimethyl sulfoxide (DMSO) is widely used in chemistry and biology as a solvent and as a cryoprotectant. It is also used as a pharmaceutical agent for the treatment of interstitial cystitis and rheumatoid arthritis. Previous reports described DMSO as being reduced by methionine-S-sulfoxide reductase (MsrA).
Geun-Hee, Kwak, Seung Hee, Choi, Jae-Ryong, Kim, Hwa-Young, Kim   +3 more
openaire   +3 more sources

Low temperature dielectric relaxation study of aqueous solutions of diethylsulfoxide

, 2014
In the present work, dielectric spectra of mixtures of diethylsulfoxide (DESO) and water are presented, covering a concentration range of 0.2 - 0.3 molar fraction of DESO.
Gabrielyan, L., Loidl, A., Lunkenheimer, P., Markarian, S.   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Benzyl 2,4-dichlorophenyl sulfoxide

Molbank
Benzyl 2,4-dichlorophenyl sulfoxide was synthesized both in racemic and in an enantiopure form. This enantiopure sulfoxide is a further successful confirmation of our straightforward protocol to yield easily chiral aryl benzyl sulfoxides.
Maria Annunziata M. Capozzi, Joan F. Piniella Febrer, Cosimo Cardellicchio   +2 more
doaj   +1 more source

Advancements in Asymmetric Synthesis of Esomeprazole and Chiral Sulfoxide Drugs: A Comprehensive Review and Future Perspectives [PDF]

E3S Web of Conferences
Chiral sulfoxides are widely present in biologically active molecules and pharmaceuticals, and their efficient and green synthesis has been a hot research topic.
Yu Jingwen
doaj   +1 more source

Modular polyoxometalate-layered double hydroxides as efficient heterogeneous sulfoxidation and epoxidation catalysts [PDF]

, 2018
Selective sulfoxidation of sulfides and epoxidation of olefins are two types of important organic reactions and the corresponding products of sulfoxides, sulfones and epoxides are widely used as raw materials in industrial processes.
Al-Maksoud, Bayat, Cai, Chen, Chen, Chen, Doherty, Dou, Fan, Graham, Guo, Herrmann, Herrmann, Herrmann, Hong, Huang, Iyi, Jia, Jia, Karimi, Karimi, Kawahara, Kon, Koo, Lechner, Leng, Li, Li, Li, Liang, Liu, Liu, Liu, Miras, Mizuno, Mizuno, Omwoma, Park, Peacock, Poli, Qiao, Salvati, Shi, Shi, Song, Venturello, Wang, Weir, Xie, Xu, Yamaguchi, Yang, Zhao, Zhao, Zhao, Zhao, Zhou, Zhou   +57 more
core   +1 more source