Results 81 to 90 of about 17,306 (293)
TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara +18 more
wiley +1 more source
Magnetically recoverable nano-catalysts in sulfoxidation reactions
The sulfoxidation of sulfides have received special attention in organic synthesis especially in medical chemistry because compounds containing S=O bonds (sulfoxides) are privileged structural scaffolds for building pharmacologically and biologically ...
Kazemi Mosstafa, Ghobadi Massoud
doaj +1 more source
The Electrochemical Oxidation of Organic Selenides and Selenoxides [PDF]
The electrochemical oxidation of alkyl and aryl selenides was investigated in acetonitrile. The oxidation of diphenyl selenide and di(4‐methylphenyl) selenide led primarily to the formation of their respective selenoxides, which were identified by ...
Hack, Michael +2 more
core +1 more source
Homoallylglycine residues are superior precursors to orthogonally modified thioether containing polypeptides. [PDF]
Homoallylglycine N-carboxyanhydride, Hag NCA, monomers were synthesized and used to prepare polypeptides containing Hag segments with controllable lengths of up to 245 repeats.
Deming, Timothy J +2 more
core +1 more source
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
Tetrahydro-4H-thiopyran-4-one 1-oxide 1 and sulfinyl-di-tert-butylpropionate 2 were reported as sources of bis-sulfenate anion and applied in a double pallado-catalyzed cross-coupling reaction for the synthesis of symmetrical biarylsulfoxides, tolerating
Valentin Magné +4 more
doaj +1 more source
Collapse models provide a theoretical framework for understanding how classical world emerges from quantum mechanics. Their dynamics preserves (practically) quantum linearity for microscopic systems, while it becomes strongly nonlinear when moving ...
Bahrami, M. +6 more
core +1 more source
Selective oxidation of sulfides to sulfoxides and sulfones using a new catalyst with Keggin type-structure (H5PMo11Al0.5V0.5O40) [PDF]
En esta investigación, se ha encontrado un nuevo y selectivo procedimiento de oxidación de sulfuros aromáticos y alifáticos, en sulfóxidos y sulfonas, empleando 35% H2O2 y acetonitrilo como solvente de reacción.
Dimitroff, Pablo +3 more
core +3 more sources
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
During aerobic respiratory growth, Bacillus cereus is exposed to continuously reactive oxidant, produced by partially reduced forms of molecular oxygen, known as reactive oxygen species (ROS).
Jean-Paul Madeira +4 more
doaj +1 more source

