Results 1 to 10 of about 13,917 (157)

Comparison of sulphonamides decomposition efficiency in ozonation and enzymatic oxidation processes [PDF]

Archives of Environmental Protection, 2021
Sulphonamides (SAs) are one of the most frequently detected anthropogenic micropollutants in the aquatic environment and their presence in it may pose a threat to living organisms.
Natalia Lemańska, Ewa Felis, Marzena Poraj-Kobielska, Zuzanna Gajda-Meissner, Martin Hofrichter   +4 more
doaj   +2 more sources

Steric Effects of N-Alkyl Group on the Base-Induced Nitrogen to Carbon Rearrangement of Orthogonally Protected N-Alkyl Arylsulphonamides [PDF]

Molecules
The rearrangement of a total of 56 members of 22 series of orthogonally protected N-alkyl arylsulphonamides of general structure 4-XC6H4SO2NR1CO2R2 [X = H, CH3, F, Cl, Br, CH3O, CN, CF3 or C(CH3)3; R1 = CH3, CH2CH3, CH2CH2CH3, CH(CH3)2 or CH2CH(CH3)2; R2
Amie Saidykhan, Jenessa Ebert, Nathan W. Fenwick, William H. C. Martin, Richard D. Bowen   +4 more
doaj   +2 more sources

Distribution, lipophilicity and tissue half-life as key factors in sulphonamide clearance from porcine tissues [PDF]

Journal of Veterinary Research
Sulphonamides are some of the most widely used antimicrobial drugs in the treatment of bacterial diseases in pigs. The study was conducted to compare the total exposure of tissue to a group of active substances in a single formulation and evaluate the ...
Burmańczuk Artur, Osypiuk Monika, Polska Bożena, Kunicki Dominik, Kocik Marcin, Grzęda Karol, Markiewicz Włodzimierz, Yilmaz Oktay, Grabowski Tomasz   +8 more
doaj   +2 more sources

Comparison of transfer of different sulphonamides from contaminated beeswax to honey [PDF]

Journal of Veterinary Research
No maximum residue limits in honey have been legislated in the EU for antimicrobial substances such as sulphonamides, and they are not permitted, therefore, for treating honey bees unless in a cascade system.
Mitrowska Kamila, Antczak Maja
doaj   +2 more sources

Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Design and synthesis of three novel series of aryl enaminones (3a–f and 5a–c) and pyrazole (4a-c) linked compounds with sulphonamides, sulfaguanidine, or carboxylic acid functionalities were reported as carbonic anhydrase inhibitors (CAIs) using the ...
Heba Abdelrasheed Allam, Mohamed E. Albakry, Walaa R. Mahmoud, Alessandro Bonardi, Shaimaa A. Moussa, Samy Mohamady, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Hany S. Ibrahim   +8 more
doaj   +1 more source

Determination of Sulphonamides and Tetracycline Residues in Liver Tissues of Broiler Chicken Sold in Kinondoni and Ilala Municipalities, Dar es Salaam, Tanzania

Antibiotics, 2022
In Tanzania, the increased demand for animal-derived foods, particularly eggs, meat, and milk, has resulted in the intensification of farming systems with the use of antimicrobials, particularly sulphonamides and tetracyclines.
Winstone J. Ulomi, Fauster X. Mgaya, Zuhura Kimera, Mecky I. Matee   +3 more
doaj   +1 more source

Simultaneous Determination of Multiple Contaminants in Chicken Liver Using Dispersive Liquid-Liquid Microextraction (DLLME) Detected by LC-HRMS/MS

Foods, 2023
Simultaneous determination of a mixture of food contaminants, including pesticides, sulphonamides, fluoroquinolones, anthelmintics, and aflatoxin B1, in solid biological samples (chicken liver) by dispersive liquid-liquid microextraction/liquid ...
Belete Eshetu Gebreyohannes, Simiso Dube, Mathew Muzi Nindi   +2 more
doaj   +1 more source

4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
A one-pot two-step protocol was developed for the synthesis of a series of novel 4-cyanamidobenzenesulfonamides from easily accessible methyl (4-sulfamoylphenyl)-carbamimidothioate.
Morteza Abdoli, Alessandro Bonardi, Claudiu T. Supuran, Raivis Žalubovskis   +3 more
doaj   +1 more source

Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In this work, different series of benzothiazole-based sulphonamides 8a-c, 10, 12, 16a-b and carboxylic acids 14a-c were developed as novel SLC-0111 analogues with the goal of generating potent carbonic anhydrase (CA) inhibitors.
Tarfah Al-Warhi, Mostafa M. Elbadawi, Alessandro Bonardi, Alessio Nocentini, Ahmed A. Al-Karmalawy, Nada Aljaeed, Ohoud J. Alotaibi, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Wagdy M. Eldehna   +9 more
doaj   +1 more source

Schiff bases of sulphonamides as a new class of antifungal agent against multidrug‐resistant Candida auris

MicrobiologyOpen, 2021
Invasive Candida infections in hospitalized and immunocompromised or critically ill patients have become an important cause of morbidity and mortality. There are increasing reports of multidrug resistance in several Candida species that cause Candidemia,
Asad Hamad, Yiyuan Chen, Mohsin A. Khan, Shirin Jamshidi, Naima Saeed, Melanie Clifford, Charlotte Hind, J. Mark Sutton, Khondaker Miraz Rahman   +8 more
doaj   +1 more source