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SUMO and SUMOylation Pathway at the Forefront of Host Immune Response
Frontiers in Cell and Developmental Biology, 2021 Pathogens pose a continuous challenge for the survival of the host species. In response to the pathogens, the host immune system mounts orchestrated defense responses initiating various mechanisms both at the cellular and molecular levels, including ...
Sajeev T. K. +5 more
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Physiological Reviews, 2020 Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates multiple biological processes, including cell division, DNA replication/repair, signal transduction, and cellular metabolism.
Hui-Ming Chang, Edward T H Yeh
exaly +2 more sources
SUMO chain formation is required for response to replication arrest in S. pombe. [PDF]
PLoS ONE, 2009 SUMO is a ubiquitin-like protein that is post-translationally attached to one or more lysine residues on target proteins. Despite having only 18% sequence identity with ubiquitin, SUMO contains the conserved betabetaalphabetabetaalphabeta fold present in
Andrew Skilton +4 more
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Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. [PDF]
Nature Communications, 2017 Small ubiquitin-like modifier (SUMO) modification regulates numerous cellular processes. Unlike ubiquitin, detection of endogenous SUMOylated proteins is limited by the lack of naturally occurring protease sites in the C-terminal tail of SUMO proteins ...
Ahmad, Alla S +8 more
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Dealing With Stress: A Review of Plant SUMO Proteases
Frontiers in Plant Science, 2019 The SUMO system is a rapid dynamic post-translational mechanism employed by eukaryotic cells to respond to stress. Plant cells experience hyperSUMOylation of substrates in response to stresses such as heat, ethanol, and drought.
Rebecca Morrell, Ari Sadanandom
doaj +2 more sources
A microscopic traffic simulation framework to evaluate the performance of bus priority lanes [PDF]
Journal of South Asian Logistics and Transport, 2023 Bus priority measures are widely considered effective at reducing traffic congestion and bus travel times. Traditionally, the performance of a bus priority measure is evaluated using traffic survey-based methods.
Thenuwan Jayasinghe +2 more
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DSRC Applicability in Cameroon Road Traffic: A Simulation Study [PDF]
EAI Endorsed Transactions on Mobile Communications and Applications, 2021 The IEEE 802.11p standard has been amended in the 5.9GHz band in 2010 to provide road safety by enabling vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) communications.
M. Zongo +3 more
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Frontiers in Oncology, 2023 Bidirectional nucleo-cytoplasmic transport, regulating several vital cellular processes, is mediated by the Nuclear Pore Complex (NPC) comprising the nucleoporin (Nup) proteins.
Usha Singh +3 more
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Journal of Medicinal Chemistry, 2021 SUMOylation is a reversible post-translational modification that regulates protein function through covalent attachment of small ubiquitin-like modifier (SUMO) proteins. The process of SUMOylating proteins involves an enzymatic cascade, the first step of
S. Langston +52 more
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SUMO Interacting Motifs: Structure and Function
Cells, 2021 Small ubiquitin-related modifier (SUMO) is a member of the ubiquitin-related protein family. SUMO modulates protein function through covalent conjugation to lysine residues in a large number of proteins.
T. Yau +3 more
semanticscholar +1 more source