Results 71 to 80 of about 291,935 (374)

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

CALIBRATION OF MICROSCOPIC TRAFFIC SIMULATION OF URBAN ROAD NETWORK INCLUDING MINI-ROUNDABOUTS AND UNSIGNALIZED INTERSECTION USING OPEN-SOURCE SIMULATION TOOL [PDF]

Scientific Journal of Silesian University of Technology. Series Transport
Microscopic traffic simulation models offer an effective way to analyze and assess different transportation systems thanks to their efficiency and reliability.
Mehmet Nedim YAVUZ, Halit ÖZEN
doaj   +1 more source

Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation. [PDF]

PLoS ONE, 2009
SUMO is a protein modifier that is vital for multicellular development. Here we present the first system-wide analysis, combining multiple approaches, to correlate the sumoylated proteome (SUMO-ome) in a multicellular organism with the developmental ...
Minghua Nie, Yongming Xie, Joseph A Loo, Albert J Courey   +3 more
doaj   +1 more source

Polyhalogenated Carbazole Impairs Dopaminergic Neurons through Dysregulation of Liquid–Liquid Phase Separation in Caenorhabditis elegans

Advanced Science, EarlyView.
Polyhalogenated carbazoles (PHCZ), persistent environmental contaminants, preferentially accumulate in neuronal tissues. Studies using Caenorhabditis elegans and human neuronal cell lines reveal that PHCZ induce dopaminergic neurodegeneration by promoting liquid–liquid phase separation of α‐synuclein, reducing condensate fluidity, impairing ...
Yuhang Luo, Hongbo Xu, Pei Peng, Xinhe Lu, Qian Zhou, Ziqing Gao, Cheng Tang, Hongyan Yin, Ying Cai, Gaga Mahai, Zhiqiang Zhu, Zuojun Liu, Hanzeng Li, Shunqing Xu   +13 more
wiley   +1 more source

Domain Modeling in the Context of Ontology

Foundations of Computing and Decision Sciences, 2015
The domain knowledge represented by ontology should be widely used in the design process of information system. The aim of the paper is to outline a systematic approach of developing a CIM model (domain model, precisely) on the basis of a selected domain
Dubielewicz Iwona, Hnatkowska Bogumiła, Huzar Zbigniew, Tuzinkiewicz Lech   +3 more
doaj   +1 more source

Gene Editing of a Susceptibility LncRNA Enhances Broad‐Spectrum Disease Resistance in Rice without Developmental Trade‐Offs

Advanced Science, EarlyView.
Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao, Ye Cheng, Jia‐hui Huang, Jun‐jie Feng, Hui‐yin Pang, Yi‐chao Qin, Zheng‐tong Chen, Yu Cheng, Jian‐ping Lian, Yan‐fei Zhou, Rui‐rui He, Meng‐qi Lei, Zi‐qin Cao, Lu Yang, Chao Yuan, Jie Jiang, Yue‐qin Chen, Yu‐chan Zhang   +17 more
wiley   +1 more source

EXTRAÇÃO DO SUMO DA BETA VULGARIS COMO ALTERNATIVA SUSTENTÁVEL NA PRODUÇÃO DE TINTAS

Revista UniVap, 2017
O trabalho apresenta a extração do sumo da beterraba a partir de um método simples ao mais complexo, sendo utilizado apenas a pigmentação arrocheada para a fabricação de tinta natural, sem corantes para que não deteriore o material.
Gabriela Camila Ribeiro, Ingrid Januário Santana, Leticia Gabriele Ereno, Maria Laura Castro Villa, Neiva Dias Ambrósio, Jobair Rangel   +5 more
doaj   +1 more source

SUMO-4: A novel functional candidate in the human placental protein SUMOylation machinery. [PDF]

PLoS ONE, 2017
BACKGROUND:Small ubiquitin-like modifiers (SUMOs) conjugate to proteins post-translationally, thereby affecting target localization, activity and stability.
Dora Baczyk, Melanie C Audette, Sascha Drewlo, Khrystyna Levytska, John C Kingdom   +4 more
doaj   +1 more source

A Photo-Crosslinking Approach to Identify Class II SUMO-1 Binders

Frontiers in Chemistry, 2022
The small ubiquitin-like modifier (SUMO) is involved in various cellular processes and mediates known non-covalent protein-protein interactions by three distinct binding surfaces, whose interactions are termed class I to class III.
Kira Brüninghoff, Stephanie Wulff, Wolfgang Dörner, Ruth Geiss-Friedlander, Henning D. Mootz   +4 more
doaj   +1 more source

SUMO and cellular adaptive mechanisms

Experimental and Molecular Medicine, 2020
The ubiquitin family member SUMO is a covalent regulator of proteins that functions in response to various stresses, and defects in SUMO-protein conjugation or deconjugation have been implicated in multiple diseases.
Hong-Yeoul Ryu, S. Ahn, M. Hochstrasser
semanticscholar   +1 more source