Results 81 to 90 of about 29,696 (227)
PLoS ONE, 2014 During embryonic development of Artemia sinica, environmental stresses induce the embryo diapause phenomenon, required to resist apoptosis and regulate cell cycle activity.
Bing Chu +9 more
doaj +1 more source
Modular Donor‐Acceptor Diradicaloids Based on an Electron Deficient N‐Heteroacene Acceptor
Small, EarlyView.This work presents a modular approach to donor‐acceptor‐donor (D‐A‐D) diradicaloids that show systematic evolution of their energy gaps, singlet‐triplet splittings, and diradical character (y). The correlation of (opto)electronic, spin, and magnetic properties with high‐fidelity theoretical investigations provides clear connections between the degree ...
Tanner L. Smith +9 more
wiley +1 more source
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT Integrating healthcare systems with intelligent transportation networks represents a critical frontier in modern urban infrastructure, where efficient resource allocation and timely service delivery can significantly impact patient outcomes.
Huamao Jiang +4 more
wiley +1 more source
Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications
mBio, 2019 Regulation of a variety of different cellular processes, including posttranslational modifications, is critical for the ability of many viruses to replicate efficiently within host cells.
Sook-Young Sohn, Patrick Hearing
doaj +1 more source
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT As a government‐regulated public service, traffic signal control (TSC) requires reliable and transparent decision‐making. However, existing deep reinforcement learning (DRL) methods, despite improvements in control accuracy, still lack explainability and generalisation, severely limiting their applicability in real‐world environments.
Hao Huang +8 more
wiley +1 more source
SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation
Cell Reports, 2013 A key feature in Huntington disease (HD) is the accumulation of mutant Huntingtin (HTT) protein, which may be regulated by posttranslational modifications.
Jacqueline Gire O’Rourke +23 more
doaj +1 more source
Commentary: Three questions for the study of traumatic brain injury in animals
The Anatomical Record, EarlyView.
Gregory Hollin
wiley +1 more source
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT This paper presents HealthNet, a novel framework for the dynamic optimisation of healthcare transportation networks using multi‐agent reinforcement learning. HealthNet leverages a spatiotemporal dependency module to capture complex spatiotemporal relationships in healthcare demand and resource allocation patterns, combined with centralised ...
Jianhui Lv +3 more
wiley +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source
Opening closed inward rectifier potassium channel doors
British Journal of Pharmacology, EarlyView.Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger +3 more
wiley +1 more source