Results 111 to 120 of about 31,613 (261)

Psoriasis‐like inflammation induces structural and functional changes in mitochondria

The FEBS Journal, EarlyView.
Psoriasis‐like inflammation, induced by IL‐17, IL‐22, and TNF‐α in keratinocytes and fibroblasts, alters mitochondrial functions, suppressing respiration and increasing mitochondrial ROS production. It also triggers mitochondrial fragmentation, swelling, and cristae disassembly, alongside enhanced secretion of proinflammatory mediators driven by ...
Gabrielė Kulkovienė, Martyna Uldukytė, Sofiya Haluts, Milda Kairytė, Jonas Šoliūnas, Viktorija Šalčiūtė, Rūta Inčiūraitė, Jurgita Skiecevičienė, Monika Iešmantaitė, Ramunė Morkūnienė, Aistė Jekabsone   +10 more
wiley   +1 more source

Proteins of the PIAS family enhance the sumoylation of the papillomavirus E1 protein [PDF]

, 2004
Germán Rosas-Acosta, Martijn A. Langereis, Adeline F. Deyrieux, Van G. Wilson   +3 more
openalex   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Sumoylation fights “aggregopathies” [PDF]

Cell Cycle, 2012
Jochen H. Weishaupt, Petranka Krumova
openaire   +2 more sources

Phosphorylation‐Induced Degradation of Pepper Dehydration‐Related Homeobox Gene 12 (CaDRHB12), a Negative Regulator of Drought Response in Pepper, by CaSnRK2.6 Enhances Drought Tolerance

Plant Biotechnology Journal, EarlyView.
ABSTRACT Homeodomain‐leucine zipper (HD‐ZIP) transcription factors, particularly subfamily I genes, are associated with drought stress responses. However, the functional roles of HD‐ZIP subfamily II genes, particularly in pepper (Capsicum annuum), remain inadequately studied, and their involvement in abscisic acid (ABA) signalling is not fully ...
Woonhee Baek, Yeongil Bae, Chae Woo Lim, Sung Chul Lee   +3 more
wiley   +1 more source

Targeting pseudokinase TRIB3 brings about a new therapeutic option for acute promyelocytic leukemia

Molecular & Cellular Oncology, 2017
Pseudokinase tribbles (Trib) family, Trib1 and Trib2, but not Trib3, act as oncogene to drive acute leukemia by destabilizing the myeloid transcription factor CCAAT/enhancer-binding protein α (C/EBPα) and inhibiting myeloid differentiation.
Ke Li, Feng Wang, Zhuo-Wei Hu
doaj   +1 more source

Dual Role of Sumoylation in the Nuclear Localization and Transcriptional Activation of NFAT1 [PDF]

, 2004
Yasuhito Terui, Natalie Saad, Shidong Jia, Frank McKeon, Junying Yuan   +4 more
openalex   +1 more source

Mapping the Phosphorylation Regulatory Network of Single‐Celled Fibre Elongation Mediated by GhBIN2 in Cotton

Plant Biotechnology Journal, EarlyView.
ABSTRACT Protein phosphorylation plays a pivotal role in cellular signal transduction and plant development. The plant steroid hormone Brassinosteroids (BRs) signal transduction relies primarily on protein kinase‐mediated phosphorylation cascades.
Le Liu, Mengli Yu, Longfei Wang, Ghulam Qanmber, Liqiang Fan, Yujun Li, Zhao Liu, Xuwen Wang, Li Liu, Fuguang Li, Shuangxia Jin, Zuoren Yang   +11 more
wiley   +1 more source

Identification of Xenopus heat shock transcription factor–2: conserved role of sumoylation in regulating deoxyribonucleic acid–binding activity of heat shock transcription factor–2 proteins [PDF]

, 2004
Roland Hilgarth, Lynea Murphy, Colleen M. O'Connor, James Clark, Ok-Kyong Park-Sarge, Kevin D. Sarge   +5 more
openalex   +1 more source

The MdGLK1‐MdBZR1 Module Integrates Ethylene and Strigolactone Signals to Regulate Cold Tolerance via a CBF‐Dependent Pathway in Apple

Plant Biotechnology Journal, EarlyView.
ABSTRACT Although ethylene and strigolactone (SL) are key regulators of cold tolerance in plants, the molecular crosstalk between their signalling pathways is poorly understood. Here, we identified the transcription factor GOLDEN2‐LIKE1 (MdGLK1) as a central integrator of ethylene and SL signalling during the apple (Malus × domestica) cold stress ...
Xiao‐Wei Zhang, Xiu‐Hong An, Rui‐Rui Xu, Yi Tian, Baoyou Liu, Yuepeng Han, Jian‐Ping An   +6 more
wiley   +1 more source