Results 51 to 60 of about 21,065 (189)

Determining the immunological characteristics of a novel human monoclonal antibody developed against staphylococcal enterotoxin B

open access: yesHuman Vaccines & Immunotherapeutics, 2020
Staphylococci are the main cause of nosocomial infections globally. The exotoxin staphylococcal enterotoxin B (SEB) produced by methicillin-resistant Staphylococcus aureus is a major cause of pathology after a staphylococcal infection.
Yuanyuan Liu   +10 more
doaj   +1 more source

New Allergens Approved by the WHO/IUIS Allergen Nomenclature Sub‐Committee in 2021–2024 and Their Significance for Future Diagnostics, Regulation, and Research. An EAACI Task Force Report

open access: yesAllergy, EarlyView.
ABSTRACT The WHO/IUIS Allergen Nomenclature Sub‐Committee is an international body of experts that maintains the systematic nomenclature of allergenic proteins by assigning official names to newly identified allergens submitted by researchers. Here, we summarize the data on new allergens approved between 2021 and 2024.
Christian Radauer   +12 more
wiley   +1 more source

Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis

open access: yesViruses, 2010
Mouse mammary tumor virus (MMTV), which was discovered as a milk‑transmitted, infectious cancer-inducing agent in the 1930s, has been used since that time as an animal model for the study of human breast cancer.
Susan R. Ross
doaj   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

open access: yesAllergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm   +9 more
wiley   +1 more source

SUPERANTIGENS

open access: yesActa agriculturae Slovenica, 1998
Superantigens are bacterial, viral, retroviral and some naturally occurring proteins that can specifically activate a large proportion of T and/or B cells. In contrast to classical peptide antigen recognition, superantigens do not require processing to small peptides.
Terje Kalland   +3 more
openaire   +3 more sources

Intact Staphylococcus Enterotoxin SEB from Culture Supernatant Detected by MALDI-TOF Mass Spectrometry

open access: yesToxins, 2019
Routine identification of pathogens by MALDI-TOF MS (matrix-assisted laser desorption ionisation time-of-flight mass spectrometry) is based on the fingerprint of intracellular proteins.
Jenna Tonacini   +7 more
doaj   +1 more source

Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. [PDF]

open access: yes, 1996
The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) and T cells that specifically recognize defined groups of polymorphic human histocompatibility leukocyte antigen (HLA) class I molecules.
Chang, C   +3 more
core  

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

Superantigens Modulate Bacterial Density during Staphylococcus aureus Nasal Colonization

open access: yesToxins, 2015
Superantigens (SAgs) are potent microbial toxins that function to activate large numbers of T cells in a T cell receptor (TCR) Vβ-specific manner, resulting in excessive immune system activation.
Stacey X. Xu   +3 more
doaj   +1 more source

Human Keratinocyte Response to Superantigens

open access: yesmSphere, 2020
Staphylococcus aureus and Streptococcus pyogenes are significant human pathogens, causing infections at multiple body sites, including across the skin. Both are organisms that cause human diseases and secrete superantigens, including toxic shock syndrome
Patrick M. Schlievert   +3 more
doaj   +1 more source

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