Results 41 to 50 of about 10,170 (163)

SUPERANTIGENS

Acta agriculturae Slovenica, 1998
Superantigens are bacterial, viral, retroviral and some naturally occurring proteins that can specifically activate a large proportion of T and/or B cells. In contrast to classical peptide antigen recognition, superantigens do not require processing to small peptides.
Terje Kalland, Mikael Dohlsten, Per Antonsson, Morten Soögaard   +3 more
openaire   +3 more sources

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

Genomic analysis and identification of a novel superantigen, SargEY, in Staphylococcus argenteus isolated from atopic dermatitis lesions

mSphere
During surveillance of Staphylococcus aureus in lesions from patients with atopic dermatitis (AD), we isolated Staphylococcus argenteus, a species registered in 2011 as a new member of the genus Staphylococcus and previously considered a lineage of S ...
Fatkhanuddin Aziz, Junzo Hisatsune, Hisaya K. Ono, Junko Kajimura, Liansheng Yu, Kanako Masuda, Hiroki Kitagawa, Yusuke Sato'o, Koji Yahara, Mika Yamaoka, Akio Nakane, Hiroshi Kawasaki, Shoko Obata, Ayano Fukushima-Nomura, Yoshihiro Ito, Meiji Soe Aung, Masayuki Amagai, Siti Isrina Oktavia Salasia, Hiroki Ohge, Yoichiro Kusunoki, Motoyuki Sugai   +20 more
doaj   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

The Systemic and Pulmonary Immune Response to Staphylococcal Enterotoxins

Toxins, 2010
In response to environmental cues the human pathogen Staphylococcus aureus synthesizes and releases proteinaceous enterotoxins. These enterotoxins are natural etiologic entities of severe food poisoning, toxic shock syndrome, and acute diseases ...
Anthony T. Vella, Sanjeev Kumar, Soo-Mun Ngoi, Antoine Ménoret   +3 more
doaj   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

Immunology, EarlyView.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur, Hubert S. Ahor, Monika M. Vivekanandan, Difery Minadzi, Augustine Yeboah, Millicent Lamptey, Victoria A. Ofori, Albert D. Kegya, Rejoice Arthur, Linda A. Amoakoa, Ernest Adankwah, Dorcas O. Owusu, Mohammed K. Abass, Fredrick Gyamfi Apraku, Nana K. Ayisi‐Boateng, Seth Adane, Salisu Zakaria, Ertan Mayatepek, Julia Seyfarth, Richard O. Phillips, Marc Jacobsen   +20 more
wiley   +1 more source

Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1

Toxins, 2017
Some Staphylococcus aureus isolates produced toxic shock syndrome toxin-1 (TSST-1) which is a pyrogenic toxin superantigen (PTSAg). The toxin activates a large fraction of peripheral blood T lymphocytes causing the cells to proliferate and release ...
Thunchanok Rukkawattanakul, Nitat Sookrung, Watee Seesuay, Nattawat Onlamoon, Pornphan Diraphat, Wanpen Chaicumpa, Nitaya Indrawattana   +6 more
doaj   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source

Staphylococcal Enterotoxin C Is an Important Virulence Factor for Mastitis

Toxins, 2019
Staphylococcus aureus is an important bacterial pathogen causing bovine mastitis, but little is known about the virulence factor and the inflammatory responses in the mammary infection.
Rendong Fang, Jingchun Cui, Tengteng Cui, Haiyong Guo, Hisaya K. Ono, Chun-Ho Park, Masashi Okamura, Akio Nakane, Dong-Liang Hu   +8 more
doaj   +1 more source