Results 61 to 70 of about 12,609 (207)

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission.

, 1993
Endogenous and infectious mouse mammary tumor viruses (MMTVs) encode in their 3' long terminal repeat a protein that exerts superantigen activity; that is, it is able to interact with T cells via the variable domain of the T cell receptor (TCR) beta ...
Acha-Orbea, H., Waanders, G.A., Shakhov, A.N., Scarpellino, L., MacDonald, H.R., Held, W.   +5 more
core   +1 more source

Staphylococcal enterotoxins in the Etiopathogenesis of Mucosal Autoimmunity within the Gastrointestinal Tract

Toxins, 2014
The staphylococcal enterotoxins (SEs) are the products of Staphylococcus aureus and are recognized as the causative agents of classical food poisoning in humans following the consumption of contaminated food.
MaryAnn Principato, Bi-Feng Qian
doaj   +1 more source

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, Volume 81, Issue 7, Page 2309-2324, July 2026.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Preparation of a superantigen-adsorbing device and its superantigen removal efficacies in vitro and in vivo

, 2003
Objective: A new superantigen-adsorbing device (SAAD) was developed, and its characteristics and efficacy in septic animals were evaluated.Methods: The SAAD was prepared by stepwise chemical modification of a polystyrene-based composite fiber reinforced ...
Nobuo Ida, Hideo Igarashi, Uchiyama, Takehiko, Fukuyama, Mayumi, Igarashi, Hideo, Mayumi Fukuyama, Miwa, Keishi, Ida, Nobuo, Keishi Miwa, Takehiko Uchiyama   +9 more
core   +1 more source

Design of PCR-based method for detection of a gene-encoding Mycoplasma arthritidis mitogen superantigen in synovial fluid of rheumatoid arthritis patients

Iranian Journal of Microbiology, 2014
Background and Objectives: Mycoplasma arthritidis mitogen (MAM) superantigen has been shown to induce chronic arthritis, which resembles human rheumatoid arthritis (RA) in a rodent model.
Reza Golmohammadi, Ramezan Ali Ataee, Gholam Hossein Alishiri, Reza Mirnejad, Ali Mehrabi-Tavana, Davoude Esmaieli   +5 more
doaj  

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, Volume 178, Issue 3, Page 417-427, July 2026.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Clinical Snapshot of Group A Streptococcal Isolates from an Australian Tertiary Hospital

Pathogens
Streptococcus pyogenes (Group A Streptococcus, GAS) is a human-restricted pathogen that causes a wide range of diseases from pharyngitis and scarlet fever to more severe, invasive infections such as necrotising fasciitis and streptococcal toxic shock ...
Phoebe K. Shaw, Andrew J. Hayes, Maree Langton, Angela Berkhout, Keith Grimwood, Mark R. Davies, Mark J. Walker, Stephan Brouwer   +7 more
doaj   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

Immunology, Volume 178, Issue 3, Page 494-505, July 2026.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur, Hubert S. Ahor, Monika M. Vivekanandan, Difery Minadzi, Augustine Yeboah, Millicent Lamptey, Victoria A. Ofori, Albert D. Kegya, Rejoice Arthur, Linda A. Amoakoa, Ernest Adankwah, Dorcas O. Owusu, Mohammed K. Abass, Fredrick Gyamfi Apraku, Nana K. Ayisi‐Boateng, Seth Adane, Salisu Zakaria, Ertan Mayatepek, Julia Seyfarth, Richard O. Phillips, Marc Jacobsen   +20 more
wiley   +1 more source

Endogenous superantigen expression controlled by a novel promoter in the MMTV long terminal repeat.

, 1993
ENDOGENOUS superantigens are encoded by the open reading frame contained within the mouse mammary tumour virus long terminal repeat (MMTV LTR). Superantigen expression results in T-cell proliferation and, during early ontogeny, T-cell deletion1,2.
Günzburg, W.H., Heinemann, F., Miethke, T., Erfle, V.F., Wintersperger, S., Wagner, H.M., Salmons, B.   +6 more
core   +1 more source