Results 81 to 90 of about 21,065 (189)

Design of PCR-based method for detection of a gene-encoding Mycoplasma arthritidis mitogen superantigen in synovial fluid of rheumatoid arthritis patients

Iranian Journal of Microbiology, 2014
Background and Objectives: Mycoplasma arthritidis mitogen (MAM) superantigen has been shown to induce chronic arthritis, which resembles human rheumatoid arthritis (RA) in a rodent model.
Reza Golmohammadi, Ramezan Ali Ataee, Gholam Hossein Alishiri, Reza Mirnejad, Ali Mehrabi-Tavana, Davoude Esmaieli   +5 more
doaj  

ICAM G241A polymorphism and soluble ICAM-1 serum levels: Evidence for an active immune process in schizophrenia [PDF]

, 2005
Objectives: We have previously reported reduced serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) in schizophrenic patients. A single-nucleotide polymorphism ( SNP) of the ICAM-1 gene was described at position 241.
Ackenheil, Manfred, Kronig, H., Möller, Hans-Jürgen, Müller, Norbert, Riedel, M., Schwarz, Markus J., Strassnig, M.   +6 more
core   +1 more source

Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies

European Journal of Immunology, Volume 55, Issue 12, December 2025.
Murine allergy model outcomes differ by sensitization route, allergen type, and mouse strain, influencing mechanisms such as IgE and mast cell involvement and the therapeutic relevance of each model. Understanding how experimental parameters shape outcomes is essential for selecting appropriate models and effectively translating findings to clinical ...
Yuka Nagata, Ryo Suzuki
wiley   +1 more source

Overview of Bacterial Protein Toxins from Pathogenic Bacteria: Mode of Action and Insights into Evolution

Toxins
Bacterial protein toxins are secreted by certain bacteria and are responsible for mild to severe diseases in humans and animals. They are among the most potent molecules known, which are active at very low concentrations. Bacterial protein toxins exhibit
Michel R. Popoff
doaj   +1 more source

Helicobacter pylori and Inflammatory Bowel Disease: Unraveling the Complex Interactions and Clinical Implications

JGH Open, Volume 9, Issue 12, December 2025.
ABSTRACT Helicobacter pylori infection has been extensively studied in relation to various gastrointestinal disorders, with emerging evidence suggesting a significant association with inflammatory bowel disease (IBD). Epidemiological studies consistently demonstrate an inverse relationship between H.
Elaheh Karimzadeh‐Soureshjani, Farab Pourhasan, Pouria Ahmadi Simab, Nabi Jomehzadeh, Ali Saeedi‐Boroujeni   +4 more
wiley   +1 more source

Immune Modulation Through Long‐Term Lacticaseibacillus rhamnosus Therapy in Home Mechanically Ventilated Patients

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Antibiotic resistance crisis drives the search for innovative antibacterial solutions. Probiotics, particularly Lacticaseibacillus rhamnosus GG ATCC 53103 (LGG), show promise in preventing bacterial infections and reducing antibiotic use. LGG has well‐documented health benefits and can strengthen the immune system, especially in chronically ill ...
Kamila Szyller, Grazyna Mlynarczyk, Beata Mlynarczyk‐Bonikowska, Janusz Sierdzinski, Joanna Styk, Michal Marusza, Wojciech Marusza   +6 more
wiley   +1 more source

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

Medicine Bulletin, Volume 1, Issue 2, Page 136-153, December 2025.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao, Ruolan Li, Jingdong Zhao, Ruiqi Sun, Shuo Zhang, Qiong Pan, Hongyan Lu, Jin Chai   +7 more
wiley   +1 more source

Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome [PDF]

, 2018
Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU ...
Booth, M.G., Brooks, Daniel, Polubothu, Padmaja, Smith, A., Young, D.   +4 more
core   +1 more source

Sycosis Barbae Treated With Bimekizumab

Australasian Journal of Dermatology, Volume 66, Issue 8, Page 486-488, December 2025.
ABSTRACT Sycosis barbae (SB) is a chronic, potentially scarring alopecia that primarily affects the beard. We report a unique case of refractory SB in a 31‐year‐old male successfully treated with bimekizumab, a dual inhibitor of interleukin (IL)‐17A and IL‐17F.
Matiar Madanchi, Riccardo Curatolo, Lorenzo S. Pelloni, Hazem A. Juratli   +3 more
wiley   +1 more source

The Systemic and Pulmonary Immune Response to Staphylococcal Enterotoxins

Toxins, 2010
In response to environmental cues the human pathogen Staphylococcus aureus synthesizes and releases proteinaceous enterotoxins. These enterotoxins are natural etiologic entities of severe food poisoning, toxic shock syndrome, and acute diseases ...
Anthony T. Vella, Sanjeev Kumar, Soo-Mun Ngoi, Antoine Ménoret   +3 more
doaj   +1 more source