Results 31 to 40 of about 620,257 (337)

Modeling the Energy Landscape of Side Reactions in the Cytochrome bc1 Complex

Frontiers in Chemistry, 2021
Much of the metabolic molecular machinery responsible for energy transduction processes in living organisms revolves around a series of electron and proton transfer processes.
Peter Husen, Ilia A. Solov’yov
doaj   +1 more source

Generation of superoxide and singlet oxygen from α-tocopherolquinone and analogues. [PDF]

, 2007
Three potential routes to generation of reactive oxygen species from a tocopherolquinone have been identified. The quinone of the water-soluble vitamin E analogue Trolox C (Trol-Q) is reduced by hydrated electron and isopropanol a hydroxyalkyl radical ...
Bisby, RH, Crisostomo, AG, Moreno, RB, Navaratnam, S, Wilkinson, JA   +4 more
core   +1 more source

Impact of Exposure to Pyraclostrobin and to a Pyraclostrobin/Boscalid Mixture on the Mitochondrial Function of Human Hepatocytes

Molecules, 2023
Fungicides are widely used in agriculture for crop protection. Succinate dehydrogenase inhibitors (SDHIs) and strobilurins inhibit mitochondria electron transport chain (ETC) in fungi, by blocking complex II and complex III, respectively.
Mélina Carbone, Barbara Mathieu, Yasmine Vandensande, Bernard Gallez   +3 more
doaj   +1 more source

Cu,Zn superoxide dismutase genes in Tribolium castaneum: evolution, molecular characterisation and gene expression during immune priming. [PDF]

, 2017
The production of reactive oxygen species (ROS) is a normal consequence of the aerobic cell metabolism. Despite their high and potentially detrimental reactivity with various biomolecules, the endogenous production of ROS is a vital part of physiological,
Bakiu, Rigers, Corr\ue0, Francesca, Ferro, Diana, Kevin, Ferro, Kurtz, Joachim, Santovito, Gianfranco   +5 more
core   +2 more sources

Superoxide Dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease [PDF]

, 2016
Parkinson disease is a debilitating and incurable neurodegenerative disorder affecting 3c1-2% of people over 65 years of age. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic
Beltramini, Mariano, Bisaglia, Marco, Bubacco, Luigi, Casella, Luigi, Ferrari, Emanuele, Filograna, Roberta, Godena, Vinay K., Sanchez Martinez, Alvaro, Whitworth, Alexander J.   +8 more
core   +1 more source

Neisseria gonorrhoeae Exposed to Sublethal Levels of Hydrogen Peroxide Mounts a Complex Transcriptional Response

mSystems, 2018
Neisseria gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection.
Sarah J. Quillin, Adam J. Hockenberry, Michael C. Jewett, H Steven Seifert   +3 more
doaj   +1 more source

Microsomal superoxide anion production and NADPH-oxidation in a series of 22 aziridinylbenzoquinones [PDF]

, 1989
Several 2,5-bis(1-aziridinyl)-1,4-benzoquinones (BABQs) can be activated to alkylating species by reduction of the quinone moiety. On the other hand, cytotoxicity of these compounds can be induced by redox cycling.
Koster, Andries Sj., Prins, Bram, Reinhoudt, David N., Verboom, Willem   +3 more
core   +3 more sources

Constraints on superoxide mediated formation of manganese oxides

Frontiers in Microbiology, 2013
Manganese (Mn) oxides are among the most reactive sorbents and oxidants within the environment, where they play a central role in the cycling of nutrients, metals, and carbon.
Deric R. Learman, Bettina M. Voelker, Andrew S. Madden, Colleen M. Hansel   +3 more
doaj   +1 more source

Bioactive Secondary Metabolites of a Marine Bacillus sp. Inhibit Superoxide Generation and Elastase Release in Human Neutrophils by Blocking Formyl Peptide Receptor 1

Molecules, 2013
It is well known that overwhelming neutrophil activation is closely related to acute and chronic inflammatory injuries. Formyl peptide receptor 1 (FPR1) plays an important role in activation of neutrophils and may represent a potent therapeutic target in
Yin-Ting Huang, Tsong-Long Hwang, Pei-Jen Chung, Jimmy Kuo, Shun-Chin Yang, Wen-Yi Chang, Chwan-Fwu Lin   +6 more
doaj   +1 more source

Systemic and local vascular inflammation and arterial reactive oxygen species generation in patients with advanced cardiovascular diseases

Frontiers in Cardiovascular Medicine, 2023
BackgroundSystemic inflammation may cause endothelial activation, mediate local inflammation, and accelerate progression of atherosclerosis. We examined whether the levels of circulating inflammatory cytokines reflect local vascular inflammation and ...
Joanna Sulicka-Grodzicka, Joanna Sulicka-Grodzicka, Piotr Szczepaniak, Piotr Szczepaniak, Ewelina Jozefczuk, Ewelina Jozefczuk, Karol Urbanski, Mateusz Siedlinski, Mateusz Siedlinski, Łukasz Niewiara, Bartłomiej Guzik, Grzegorz Filip, Bogusław Kapelak, Karol Wierzbicki, Mariusz Korkosz, Tomasz J. Guzik, Tomasz J. Guzik, Tomasz J. Guzik, Tomasz P. Mikolajczyk, Tomasz P. Mikolajczyk, Tomasz P. Mikolajczyk   +20 more
doaj   +1 more source