Results 31 to 40 of about 526,315 (198)

Bioactive Secondary Metabolites of a Marine Bacillus sp. Inhibit Superoxide Generation and Elastase Release in Human Neutrophils by Blocking Formyl Peptide Receptor 1

Molecules, 2013
It is well known that overwhelming neutrophil activation is closely related to acute and chronic inflammatory injuries. Formyl peptide receptor 1 (FPR1) plays an important role in activation of neutrophils and may represent a potent therapeutic target in
Yin-Ting Huang, Tsong-Long Hwang, Pei-Jen Chung, Jimmy Kuo, Shun-Chin Yang, Wen-Yi Chang, Chwan-Fwu Lin   +6 more
doaj   +1 more source

Effect of 7-nitroindazoleon superoxide production and MnSOD activity in threat brain following kainate-induced neurotoxicity [PDF]

Archives of Biological Sciences, 2008
We investigated the effect of 7-nitroindazole (7-NI), a selective neuronal nitric oxide synthase inhibitor in vivo, on superoxide concentration as well its influence on mitochondrial MnSOD activity since this activity is associated with the production of
Radenović Lidija
doaj   +1 more source

Identification of a core set of rhizobial infection genes using data from single cell-types

Frontiers in Plant Science, 2015
Genome-wide expression studies on nodulation have varied in their scale from entire root systems to dissected nodules or root sections containing nodule primordia.
Da-Song eChen, Cheng-wu eLiu, Sonali eRoy, Donna eCousins, Nicola eStacey, Jeremy Dale Murray   +5 more
doaj   +1 more source

Making Sense of Oxidative Stress in Obstructive Sleep Apnea: Mediator or Distracter in Brain Injury?

Frontiers in Neurology, 2012
Obstructive sleep apnea is increasingly recognized as an important contributor to cognitive impairment, metabolic derangements and cardiovascular disease and mortality.
Jing eZhang, Sigrid eVeasey
doaj   +1 more source

^•BMPO-OOH Spin-Adduct as a Model for Study of Decomposition of Organic Hydroperoxides and the Effects of Sulfide/Selenite Derivatives. An EPR Spin-Trapping Approach

Antioxidants, 2020
Lipid hydroperoxides play an important role in various pathophysiological processes. Therefore, a simple model for organic hydroperoxides could be helpful to monitor the biologic effects of endogenous and exogenous compounds.
Anton Misak, Vlasta Brezova, Marian Grman, Lenka Tomasova, Miroslav Chovanec, Karol Ondrias   +5 more
doaj   +1 more source

Investigating the Potential of Conjugated Selenium Redox Folic Acid as a Treatment for Triple Negative Breast Cancer

Antioxidants, 2020
Previous studies have demonstrated that redox selenium compounds arrest cancer cell viability in vitro through their pro-oxidative activity by generating superoxide (O2•−).
Soni Khandelwal, Mallory Boylan, Gilbert Kirsch, Julian E. Spallholz, Lauren S. Gollahon   +4 more
doaj   +1 more source

Depth-resolved photochemical production of hydrogen peroxide in the global ocean using remotely sensed ocean color

Frontiers in Remote Sensing, 2022
Hydrogen peroxide (H2O2) is an important reactive oxygen species (ROS) in natural waters, affecting water quality via participation in metal redox reactions and causing oxidative stress for marine ecosystems.
Yuting Zhu, Leanne C. Powers, David J. Kieber, William L. Miller   +3 more
doaj   +1 more source

Endothelin-1 Enhances Superoxide and Prostaglandin E2 Production of Isolated Diabetic Glomeruli

Kaohsiung Journal of Medical Sciences, 2010
Endothelin-1 (ET-1) plays an important role in the pathogenic mechanism of diabetic nephropathy. However, the regulatory effects of ET-1 on superoxide and prostaglandin E2 (PGE2) in diabetic glomeruli are unclear.
Jia-Jung Lee, Chi-Chih Hung, Jer-Chia Tsai, Hung-Chun Chen   +3 more
doaj   +1 more source

Hydrogen peroxide-independent generation of superoxide by plant peroxidase: Hypotheses and supportive data employing ferrous ion as a model stimulus

Frontiers in Plant Science, 2014
When plants are threaten by microbial attacks or treated with elicitors, alkalization of extracellular space is often induced and thus pH-dependent extracellular peroxidase-mediated oxidative burst reportedly takes place, especially at the site of ...
Makoto eKimura, Yosuke eUmemoto, Tomonori eKawano   +2 more
doaj   +1 more source

The influence of reactive oxygen species on local redox conditions in oxygenated natural waters

Frontiers in Earth Science, 2016
Redox conditions in natural waters are a fundamental control on biogeochemical processes and ultimately many ecosystem functions. While the dioxygen/water redox couple controls redox thermodynamics in oxygenated aquatic environments on geological ...
Andrew Rose
doaj   +1 more source