Results 131 to 140 of about 11,924,151 (347)

The Impact of Subsidies on Czech Firms [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2013
In the Czech Republic there has been invested a lot of money to the human capital through the European Social Fund. The Human Resources and Employment Operational Programme plays an important role by providing subsidies for the training of employees and ...
Oto Potluka   +4 more
doaj  

Who writes the pay slip? Do R&D subsidies merely increase researcher wages?. [PDF]

open access: yes
Government intervention in private R&D activity is common practice nowadays. However, its impact may not be unambiguously positive. First, companies may simply replace private R&D budgets with the public R&D grant.
Aerts, Kris
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Mentoring Programmes as a successful instrument for career development of people with disabilities and disadvantaged [PDF]

open access: yes, 2007
[Excerpt] For many years the Mentoring, as a form of support for young people without work experience, is well-known practice. In the past ten years the Mentoring has proved itself as a wide-applied method of support in the career of people with ...
Leonardo da Vinci Pilot Projects
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Assessing Market-Based Solutions: Lessons from Evaluating a Youth Employment Initiative [PDF]

open access: yes, 2016
Over the last few years, The Rockefeller Foundation – working with other funders, industry associations, governments and networks – has supported a portfolio of grantees to test a range of models for training, employing, and supporting low-income youth ...
Edward T. Jackson, Karim Harji
core  

Effect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial

open access: yesJAMA psychiatry, 2018
L. Davis   +9 more
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy