The Impact of Subsidies on Czech Firms [PDF]
In the Czech Republic there has been invested a lot of money to the human capital through the European Social Fund. The Human Resources and Employment Operational Programme plays an important role by providing subsidies for the training of employees and ...
Oto Potluka +4 more
doaj
Supported employment interventions for workplace mental health of persons with mental disabilities in low-to-middle income countries: A scoping review. [PDF]
Mavindidze E, Nhunzvi C, Van Niekerk L.
europepmc +1 more source
Who writes the pay slip? Do R&D subsidies merely increase researcher wages?. [PDF]
Government intervention in private R&D activity is common practice nowadays. However, its impact may not be unambiguously positive. First, companies may simply replace private R&D budgets with the public R&D grant.
Aerts, Kris
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Critical elements in the experience of virtual reality job interview training for unemployed individuals with serious mental illness: Implications for IPS supported employment. [PDF]
Blajeski SM +7 more
europepmc +1 more source
Mentoring Programmes as a successful instrument for career development of people with disabilities and disadvantaged [PDF]
[Excerpt] For many years the Mentoring, as a form of support for young people without work experience, is well-known practice. In the past ten years the Mentoring has proved itself as a wide-applied method of support in the career of people with ...
Leonardo da Vinci Pilot Projects
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Assessing Market-Based Solutions: Lessons from Evaluating a Youth Employment Initiative [PDF]
Over the last few years, The Rockefeller Foundation – working with other funders, industry associations, governments and networks – has supported a portfolio of grantees to test a range of models for training, employing, and supporting low-income youth ...
Edward T. Jackson, Karim Harji
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source

