Results 91 to 100 of about 36,798 (270)
Calcium dynamics and circadian rhythms in suprachiasmatic nucleus neurons [PDF]
, 2004 The hypothalamic suprachiasmatic nucleus (SCN) has a pivotal role in the mammalian circadian clock. SCN neurons generate circadian rhythms in action potential firing frequencies and neurotransmitter release, and the core oscillation is thought to be ...
Brini M +5 more
core +2 more sources
Experimental Physiology, EarlyView.ABSTRACT Gastrointestinal conditions such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) are characterized by alterations in physiological and immune functions. Given the circadian clock influences gastrointestinal physiology and immunity, we hypothesized that the peripheral circadian clock is altered in these patients and ...
Sophie Fowler +12 more
wiley +1 more source
Journal of Circadian Rhythms, 2015 The mammalian circadian clock is composed of single-cell oscillators. Neurochemical and electrical signaling among these oscillators is important for the normal expression of circadian rhythms.
Katherine J. Burton +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
CIRCADIAN RHYTMICITY AND DEPRESSION
Zdravniški Vestnik, 2008 BACKGROUND Depression is the most common psychiatric syndrome treated on the primary level. Abnormal patterns of circadian rhythms are associated with a large variety of affective disorders including depression.
Peter Pregelj
doaj
Differential effects of sex and age on daily and infradian rhythms of mice
The Journal of Physiology, EarlyView.Abstract figure legend Summary of age‐ and sex‐dependent differences in behavioural rhythmicity and environmental adaptation in mice. Middle‐aged mice of both sexes show weight loss and increased daytime activity compared with young adults. In males, circadian timing remains precise with a strong 10‐day infradian rhythm across ages.
Pishan Chang +8 more
wiley +1 more source
Nature Communications, 2019 The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely ...
Ryan Hamnett +3 more
doaj +1 more source
Loss of dopamine disrupts circadian rhythms in a mouse model of Parkinson's disease
Neurobiology of Disease, 2014 Although a wide range of physiological functions regulated by dopamine (DA) display circadian variations, the role of DA in the generation and/or modulation of these rhythms is unknown.
Karim Fifel, Howard M. Cooper
doaj +1 more source
It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]
, 2016 The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core +2 more sources
Journal of Pineal Research, Volume 78, Issue 2, March 2026.ABSTRACT Circadian rhythm alignment depends on environmental light detection via opsins. Pinopsin, originally identified in the pineal organ of birds and later in amphibian pineal complex and eyes, may play a role in this process, though its function has not been genetically tested.
Neda Heshami +4 more
wiley +1 more source