Results 81 to 90 of about 36,798 (270)

The choroid plexus is an important circadian clock component

Nature Communications, 2018
The suprachiasmatic nucleus (SCN) has been thought of as the master circadian clock, but peripheral circadian clocks do exist. Here, the authors show that the choroid plexus displays oscillations more robust than the SCN and that can be described as a ...
Jihwan Myung, Christoph Schmal, Sungho Hong, Yoshiaki Tsukizawa, Pia Rose, Yong Zhang, Michael J. Holtzman, Erik De Schutter, Hanspeter Herzel, Grigory Bordyugov, Toru Takumi   +10 more
doaj   +1 more source

Physiological Implications of Prolonged Selenium Administrations in Normal and Desynchronized Adult Female Rats [PDF]

Journal of Krishna Institute of Medical Sciences University, 2021
Background: Owing to the non-biodegradability of selenium, its prolonged consumption may lead to adverse health outcomes. Aim and Objectives: The study investigated the physiological effects of prolonged selenium administrations in normal and ...
M.J. Adeniyi, F.O. Agoreyo, S.F. Ige, O.A. Fabunmi, O.P. Ozolua, S.A. Biliaminu   +5 more
doaj  

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Riding the Rhythm of Melatonin Through Pregnancy to Deliver on Time

Frontiers in Endocrinology, 2019
Pregnancy is influenced by the circadian (“circa” or approximately; diēm or day) system, which coordinates physiology and behavior with predictable daily changes in the environment such as light/dark cycles.
Ronald McCarthy, Emily S. Jungheim, Justin C. Fay, Keenan Bates, Erik D. Herzog, Sarah K. England   +5 more
doaj   +1 more source

Alterations of clock gene RNA expression in brain Regions of a triple transgenic model of Alzheimer's Disease [PDF]

, 2017
A disruption to circadian rhythmicity and the sleep/wake cycle constitutes a major feature of Alzheimer's disease (AD). The maintenance of circadian rhythmicity is regulated by endogenous clock genes and a number of external Zeitgebers, including light ...
@corresponding, Author, Bellanti, Francesco, Blonda, Maria, Calcagnini, Silvio, Cassano, Tommaso, Gaetani, Silvana, Giudetti, Anna Maria, Iannelli, Giuseppina, Mazzoccoli, Gianluigi, Romano, Adele, Serviddio, Gaetano, Tamborra, Rosanna, Vendemiale, Gianluigi, Villani, Rosanna, Vinciguerra, Manlio   +14 more
core   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source

Extraordinary behavioral entrainment following circadian rhythm bifurcation in mice. [PDF]

, 2016
The mammalian circadian timing system uses light to synchronize endogenously generated rhythms with the environmental day. Entrainment to schedules that deviate significantly from 24 h (T24) has been viewed as unlikely because the circadian pacemaker ...
Gorman, Michael R, Harrison, Elizabeth M, Johnson, Jeremy, Poonawala, Qays, Sun, Jonathan, Walbeek, Thijs J   +5 more
core   +2 more sources

Impacts of exercise, renin–angiotensin system modulation or both on skeletal muscle circadian gene expression

Experimental Physiology, EarlyView.
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro, Liliana C. Baptista, Taylor Taylor, Abbi R. Hernandez, Anisha Banerjee, Yi Sun, YouFeng Yang, Qiuhong Li, Thomas W. Buford   +8 more
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

The Role of Mammalian Glial Cells in Circadian Rhythm Regulation

Neural Plasticity, 2017
Circadian rhythms are biological oscillations with a period of about 24 hours. These rhythms are maintained by an innate genetically determined time-keeping system called the circadian clock.
Donají Chi-Castañeda, Arturo Ortega
doaj   +1 more source