Results 101 to 110 of about 1,901 (173)
Structural Analysis of Sur2391-582 and Discovery of a New ESX-Binding Core of Sur2, Sur2384-521
, 2012 HER2 is overexpressed in metastatic breast cancer and various types of cancer. HER2 is a biomarker indicating poor prognosis and high rate of recurrence. Various types of drugs targeting HER for cancer treatment have been developed.
전경화
core
Expression, purification and structural analyses of Sur2 protein containing binding core for ESX
, 2011 유방암은 전 세계 여성들에게 발생되는 암이다. 여성 유방암 환자 중 약 30% 정도는 Her2 (human epidermal growth factor receptor 2) 양성 유방암 환자이다. Her2는 인체에서 epidermal growth factor receptor (EGFR : also known as ErbB)의 tyrosine kinases receptor family 중의 하나로 알려져 있다.
김은영
core
, 1996 We have cloned an isoform of the sulfonylurea receptor (SUR), designated SUR2. Coexpression of SUR2 and the inward rectifier K+ channel subunit Kir6.2 in COS1 cells reconstitutes the properties of KATP channels described in cardiac and skeletal muscle ...
Bryan, Joseph +6 more
core +1 more source
KATP channel subunits are expressed in the epididymal epithelium in several mammalian species.
, 2008 Adenosine triphosphate-sensitive K(++) (K(ATP)) channels are poorly characterized in the reproductive tract. The present study was designed to evaluate the putative expression of K(ATP) channel subunits (Kir6.x and SURx) in the epididymis from different ...
Petein, Michel +5 more
core +1 more source
The role of survivin2 in primitive hematopoiesis during zebrafish development
, 2009 Survivin is an inhibitor of apoptosis and its role in embryonic development is not completely understood. In zebrafish, survivin undergoes gene duplication. Survivin1 (sur1) has been shown to mediate angiogenesis but not hematopoiesis.
Chung, MIS +3 more
core +1 more source
Figure 1: Selective Ablation of
, 2019 (A)Abcc9 encodes sulfonylurea receptor 2 (SUR2), the major SUR expressed in the myocardium. Shown is a schematic of Abcc9-produced transcripts encoding SUR2 full-length and SUR2-55KDa forms. Exon 5 is shown in red. (B) Shown is a depiction of full-length
Michele Hadhazy (2697553) +9 more
core +1 more source
Regional SURx subunit transcription in the mouse heart.
, 2013 Relative mRNA expression of SUR1 and SUR2 obtained in atrial and ventricular tissue (n = 3 hearts each). Expression (normalized to Hprt) was assessed by quantitative RT-PCR.
Willliam C. Claycomb (314777) +3 more
core +1 more source
Ontogeny of sulfonylurea-binding regulatory subunits of KATP channels in the pregnant rat myometrium
, 2011 ATP-sensitive potassium channels (KATPchannels) are composed of sulfonylurea receptors (SURs) and potassium inward rectifiers (Kir6.x) that assemble to form a large octameric channel.
N Lovasz, E Ducza, R Gaspar, G Falkay
core +1 more source
, 2015 ATP-sensitive potassium (KATP) channels are composed of inward-rectifying potassium channel pore-forming subunits (Kir6.1 and Kir6.2, encoded by KCNJ8 and KCNJ11, respectively) and regulatory sulfonylurea receptor subunits (SUR1 and SUR2, encoded by ...
Cooper, Paige
core +1 more source
, 2020 ATP-sensitive K ϩ (K ATP ) channel openers are vasodilators that activate both plasma membrane and mitochondrial K ATP channels. Here, we investigated the molecular mechanisms by which diazoxide and pinacidil induce vasodilation by studying diameter ...
Elizabeth M Mcnally +2 more
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