Results 51 to 60 of about 985,929 (323)

Tissue Distribution of Surfactant Proteins A and D in the Mouse [PDF]

Journal of Histochemistry & Cytochemistry, 2002
Surfactant proteins A and D, collagen-like lectins (collectins), were first isolated from the lung. In the lung, SP-A and SP-D have roles in surfactant homeostasis and innate immunity. In this study we show that SP-A and SP-D mRNA can be detected in a significant number of non-pulmonary tissues but the proteins have a more limited distribution.
Jennifer, Akiyama, Ari, Hoffman, Cynthia, Brown, Lennell, Allen, Jess, Edmondson, Francis, Poulain, Samuel, Hawgood   +6 more
openaire   +2 more sources

Surfactant Protein D as a Potential Biomarker and Therapeutic Target in Ovarian Cancer

Frontiers in Oncology, 2019
Surfactant protein D (SP-D) is an important innate immune molecule that is involved in clearing pathogens and regulating inflammation at pulmonary as well as extra-pulmonary sites.
J. Kumar, V. Murugaiah, G. Sotiriadis, Anuvinder Kaur, J. Jeyaneethi, Isotta Sturniolo, F. Alhamlan, J. Chatterjee, M. Hall, U. Kishore, E. Karteris   +10 more
semanticscholar   +1 more source

Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults

Immunity, Inflammation and Disease, 2022
Background Surfactant Protein D (SP‐D) is a pattern recognition molecule belonging to the family of collectins expressed in multiple human organ systems, including the lungs.
Benjamin Hoffmann‐Petersen, Raymond Suffolk, Jens J. H. Petersen, Thomas H. Petersen, Charlotte Brasch‐Andersen, Arne Høst, Susanne Halken, Grith L. Sorensen, Lone Agertoft   +8 more
doaj   +1 more source

Surfactant proteins A and D in Eustachian tube epithelium [PDF]

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2001
Surfactant protein (SP) A and SP-D are collectins that have roles in host defense. The Eustachian tube (ET) maintains the patency between the upper airways and the middle ear. Dysfunction of local mucosal immunity in ET may predispose infants to recurrent otitis media. We recently described preliminary evidence of the expression of SP-A and SP-D in the
Paananen, R., Sormunen, R., Glumhoff, V., van Eijk, M., Hallman, M.   +4 more
openaire   +3 more sources

The Role and Molecular Mechanism of Action of Surfactant Protein D in Innate Host Defense Against Influenza A Virus

Frontiers in Immunology, 2018
Influenza A viruses (IAVs) continue to pose major risks of morbidity and mortality during yearly epidemics and periodic pandemics. The genomic instability of IAV allows it to evade adaptive immune responses developed during prior infection. Of particular
I-Ni Hsieh, Xavier de Luna, M. White, K. Hartshorn   +3 more
semanticscholar   +1 more source

Comparative evaluation of heterologous production systems for recombinant pulmonary surfactant protein D

Frontiers in Immunology, 2014
Commercial surfactant products derived from animal lungs are used for the treatment of respiratory diseases in premature neonates. These products contain lipids and the hydrophobic surfactant proteins B and C, which help to lower the surface tension in ...
Daniela eSalgado, Rainer eFischer, Rainer eFischer, Stefan eSchillberg, Richard M Twyman, Stefan eRasche   +5 more
doaj   +1 more source

Biomarkers of Air-Blood Barrier Damage In COVID-19

Общая реаниматология, 2021
The search for sensitive and specific markers enabling timely identification of patients with a life-threatening novel coronavirus infection (COVID-19) is important for a successful treatment.The aim of the study was to examine the association of ...
M. B. Khadzhieva, A. S. Gracheva, A. V. Ershov, Yu. V. Chursinova, V. A. Stepanov, L. S. Avdeikina, O. A. Grebenchikov, A. S. Babkina, A. K. Shabanov, A. V. Tutelyan, S. S. Petrikov, A. N. Kuzovlev   +11 more
doaj   +1 more source

Green Production of Anionic Surfactant Obtained from Pea Protein [PDF]

, 2011
A pea protein isolate was hydrolyzed by a double enzyme treatment method in order to obtain short peptide sequences used as raw materials to produce lipopeptides-based surfactants.
A Clemente, A Tsoukala, A Villanueva, AF Dexter, Bénédicte Portet, C Megias, C Rondel, Caroline Rondel, CN Mulligan, D Kitamoto, EA Pena-Ramos, FM Netto, Françoise Silvestre, H Frister, H Schägger, Isabelle Alric, J Vioque, Jean-François Blanco, JS Hamada, JY Lee, K Pommer, K Yasamatsu, LA Graaf De, LM Humiski, M Dall Aaslyng, M Karamac, M Le Gall, MC Marquez, MPC Silvestre, MR Infante, P Anastas, PM Nielsen, R Amarowicz, R Sanchez-Vioque, R Sanchez-Vioque, R Sinha, RT Swank, S Jung, TS Padmashree, UK Laemmli, Zéphirin Mouloungui   +40 more
core   +2 more sources

Fungal melanin stimulates surfactant protein D–mediated opsonization of and host immune response to Aspergillus fumigatus spores

Journal of Biological Chemistry, 2018
Surfactant protein D (SP-D), a C-type lectin and pattern-recognition soluble factor, plays an important role in immune surveillance to detect and eliminate human pulmonary pathogens.
S. Wong, M. Rani, Eswari Dodagatta-Marri, O. Ibrahim‐Granet, U. Kishore, J. Bayry, J. Latgé, A. Sahu, T. Madan, V. Aimanianda   +9 more
semanticscholar   +1 more source

Surfactant protein D in the female genital tract [PDF]

Molecular Human Reproduction, 2004
Surfactant protein D (SP-D) plays a role in innate immunity against various pathogens and in vivo studies have demonstrated that SP-D also has anti-inflammatory properties. SP-D was originally demonstrated in alveolar type II cells, but recent studies have shown extrapulmonary expression of SP-D indicating a systemic role for the protein.
Leth-Larsen, Rikke, Floridon, C, Nielsen, O, Holmskov, U   +3 more
openaire   +3 more sources