Results 51 to 60 of about 17,566,312 (293)

Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults

open access: yesImmunity, Inflammation and Disease, 2022
Background Surfactant Protein D (SP‐D) is a pattern recognition molecule belonging to the family of collectins expressed in multiple human organ systems, including the lungs.
Benjamin Hoffmann‐Petersen   +8 more
doaj   +1 more source

Surfactant protein D in the female genital tract [PDF]

open access: yesMolecular Human Reproduction, 2004
Surfactant protein D (SP-D) plays a role in innate immunity against various pathogens and in vivo studies have demonstrated that SP-D also has anti-inflammatory properties. SP-D was originally demonstrated in alveolar type II cells, but recent studies have shown extrapulmonary expression of SP-D indicating a systemic role for the protein.
Leth-Larsen, Rikke   +3 more
openaire   +3 more sources

Biomarkers of Air-Blood Barrier Damage In COVID-19

open access: yesОбщая реаниматология, 2021
The search for sensitive and specific markers enabling timely identification of patients with a life-threatening novel coronavirus infection (COVID-19) is important for a successful treatment.The aim of the study was to examine the association of ...
M. B. Khadzhieva   +11 more
doaj   +1 more source

Potential Therapeutic Applications of Pulmonary Surfactant Lipids in the Host Defence Against Respiratory Viral Infections

open access: yesFrontiers in Immunology, 2021
Pulmonary surfactant is a complex and highly surface-active material. It covers the alveolar epithelium and consists of 90% lipids and 10% proteins. Pulmonary surfactant lipids together with pulmonary surfactant proteins facilitate breathing by reducing ...
Jianjian Ji   +7 more
doaj   +1 more source

Surfactant protein D binding to alveolar macrophages [PDF]

open access: yesBiochemical Journal, 1994
Surfactant protein D (SP-D) is a lung-specific protein, synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins; each member of this group has an unusual overall structure consisting of multiple globular ‘head’ regions (which contain the C-type lectin domains) linked by triple-helical, collagen-like ...
K, Miyamura   +5 more
openaire   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Surfactant Apoprotein D in Preterm Neonates with Acute Respiratory Distress Syndrome

open access: yesОбщая реаниматология, 2009
Objective: to study the production of surfactant apoprotein D in preterm neonates with acute respiratory distress syndrome (ARDS) during artificial ventilation (AV). Subjects and methods.
S. A. Perepelitsa   +6 more
doaj   +1 more source

Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis [PDF]

open access: yesТерапевтический архив, 2018
The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim.
V D Beketov   +9 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Surfactant protein D in human lung diseases [PDF]

open access: yesEuropean Journal of Clinical Investigation, 2006
AbstractThe lung is continuously exposed to inhaled pollutants, microbes and allergens. Therefore, the pulmonary immune system has to defend against harmful pathogens, while an inappropriate inflammatory response to harmless particles must be avoided.
D, Hartl, M, Griese
openaire   +2 more sources

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