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World Journal of Microbiology and Biotechnology, 2021
Lipopeptides are important secondary metabolites produced by microbes. They find applications in environmental decontamination and in the chemical, pharmaceutical and food industries. However, their production is expensive. In the present work we propose three strategies to lower the production costs of surfactin.
Thais de Carvalho Silveira +10 more
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Lipopeptides are important secondary metabolites produced by microbes. They find applications in environmental decontamination and in the chemical, pharmaceutical and food industries. However, their production is expensive. In the present work we propose three strategies to lower the production costs of surfactin.
Thais de Carvalho Silveira +10 more
openaire +3 more sources
Synthesis of Aza-Surfactin and 3-Epi-Aza-Surfactin
HETEROCYCLES, 2012Two synthetic approaches to aza surfactins are reported. In the first our recently developed synthesis of unnatural ß3 amino acids was used to prepare the requisite monomer which was used in solid phase peptide synthesis and followed by macrolactamization of a partially protected precursor. In the second the corresponding ß3 N hydroxyaminoacid was used
Jeffrey W. Bode +3 more
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Recent trends in the biochemistry of surfactin
Applied Microbiology and Biotechnology, 1999The name surfactin refers to a bacterial cyclic lipopeptide, primarily renowned for its exceptional surfactant power since it lowers the surface tension of water from 72 mN m-1 to 27 mN m-1 at a concentration as low as 20 microM. Although surfactin was discovered about 30 years ago, there has been a revival of interest in this compound over the past ...
Peypoux, F, Bonmatin, J, Wallach, J.
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Interfacial properties of surfactin
Journal of Colloid and Interface Science, 1992Abstract Surfactin is a lipopeptide produced by various strains of Bacillus subtilis and is a very powerful surfactant. Here we present the first report on the interfacial behavior of surfactin. The adsorption, Γmax, of surfactin at the interface of diluted solutions (5 × 10−8 to 5 × 10−7M) is around 3 × 1018 molecule m−2, a value indicating that ...
Régine Maget-Dana, Marius Ptak
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Hydrolysis of surfactin over activated carbon
Bioorganic Chemistry, 2019Surfactin is obtained through biocatalysis by microorganisms. In our biorefinery concept, it is purified on activated carbon (AC) during downstream processing. Besides cyclic surfactin, it is possible to obtain linear surfactin analogues, when AC with specific properties is used.
Hanna, Fałtynowicz +4 more
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Surfactin at the Water/Air Interface and in Solution
Langmuir, 2015The lipopeptide surfactin produced by certain strains of Bacillus subtillis is a potent biosurfactant with high amphiphilicity and a strong tendency for self-aggregation. Surfactin possesses a number of valuable biological properties such as antiviral, antibacterial, antifungal, and hemolytic activities.
Iglesias-Fernández, Javier +5 more
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Interaction of the Biosurfactant, Surfactin with Betaines in Aqueous Solution
Langmuir, 2013The interactions between the lipopeptide Surfactin and four betaines, N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (SDDAB), N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (STDAB), N-hexadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (SHDAB), and N-dodecyl-N,N-dimethyl-2-ammonio-acetate (C12BE) are studied by surface tension and small ...
Fang, Liu +6 more
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Surfactin variants for intra-intestinal delivery of insulin
European Journal of Pharmaceutics and Biopharmaceutics, 2017Surfactin is a Bacillus-produced natural lipopeptide, which can overcome the epithelial cell barriers for orally delivering insulin, but its ability to promote uptake of insulin by the intestine need to be further improved for a higher oral bioavailability.
Li, Zhang +4 more
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Surfactin Activity Depends on the Membrane Dipole Potential
Langmuir, 2010The effect of dipole modifying agents phloretin and RH 421 on the membrane conductance induced by surfactin, a lipopeptide antibiotic from Bacillus subtilis, was studied. Surfactin added on both sides of a bilayer formed from diphytanoylphosphocholine in 1 M KCl (pH 6.5) leads to the formation of voltage-independent channels of different conductance ...
Olga S, Ostroumova +3 more
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Toxicity and applications of surfactin for health and environmental biotechnology
Journal of Toxicology and Environmental Health, Part B, 2018Characterized as one of the most potent biosurfactants, surfactin is a cyclic lipopeptide synthesized by several strains of Bacillus genus. The aim of this review was to present the physicochemical and structural properties of surfactin and to demonstrate advances and applications of this biosurfactant for health and environmental biotechnology ...
Vanessa Santana Vieira, Santos +2 more
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