Results 71 to 80 of about 1,931 (193)

Diastereoselective Entry to Novel Aminoindolizidines with Fused Furan, Thiophene, and Pyrrole Ring Starting from L‐Glutamic Acid

European Journal of Organic Chemistry, Volume 28, Issue 6, February 10, 2025.
A series of novel aminoindolizidines fused to (tetrahydro)furan, thiophene or pyrrole nuclei were synthesized using a concise and diastereoselective approach from optically pure tricyclic heteroaryl‐indolizidinols as key substrates. The synthesis involved Jurjew‐type skeletal rearrangement, Staudinger reduction, Thompson azidation and Ra−Ni mediated ...
Paula Fraňová, Peter Šafář, Ján Moncoľ, Ivana Žídeková, Adam Daïch, Štefan Marchalín   +5 more
wiley   +1 more source

A convenient approach to (-)-8-epi-swainsonine

, 2007
A novel and efficient synthesis of (-)-8-epi-swainsonine 2 is reported. Face selective diol formation from the bicyclic alkene 3 followed by a stereoselective vinylation of the aldehyde and ring closing metathesis gave the indolizidine ring system which ...
Adrian J Murray (16063691), Peter Hitchcock (2466562), Philip J Parsons (16059035)   +2 more
core   +1 more source

Evaluation of Metabolites and Biological Activities of Areca Nut (Areca catechu L.) Under Different pH: Untargeted Mass Spectrometry–Based Metabolomics Approach

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Chewing areca nuts (ANs) produces a mild sense of excitement and happiness, particularly under alkaline conditions. To identify the substances responsible for these effects, we conducted a nontargeted metabolomics analysis comparing AN metabolites at different pH levels. Subsequently, AN’s active components were determined, and the in vitro antioxidant
Jing Zhang, Jiahui Dai, Shiping Wang, Kai Rui, Wenting Dai, Xiaoning Kang, Jianbang Ji, Weizhong Wang, Piyush Kashyap   +8 more
wiley   +1 more source

SYNTHESIS OF TWO STEREOISOMERS OF SWAINSONINE [PDF]

Chemistry Letters, 1985
Abstract Two stereoisomers of swainsonine, (1S,2S,8S,8aR)-1,2,8-trihydroxyoctahydroindolizine and the corresponding (1S,2R,8S,8aR) derivative, were synthesized from d-glucose via one step cyclization to the 5-oxo-1,2,8-trihydroxyoctahydroindolizine derivative.
Nobuyoshi Yasuda, Hideo Tsutsumi, Takao Takaya   +2 more
openaire   +1 more source

Impact of invasive alien plants on the resident floral diversity in Koshi Tappu Wildlife Reserve, Nepal

Ecology and Evolution, Volume 14, Issue 10, October 2024.
Abstract Invasive alien plant species (IAPS) pose a serious threat to overall plant biodiversity across the globe. Nepal's national parks and protected areas are not devoid of the impact of IAPS. Unfortunately, there is a substantial gap in knowledge regarding the extent and impact of invasion in protected areas of Nepal. This study assessed the impact
Divya Bhattarai, Saurav Lamichhane, Aayoush Raj Regmi, Khagendra Prasad Joshi, Pratik Pandeya, Bijaya Dhami, Ambika Prasad Gautam, Hari Adhikari   +7 more
wiley   +1 more source

Chiral Acetal‐Based Stereo‐Controlled Degradable Polymer Synthesis

Chemistry – A European Journal, Volume 30, Issue 49, September 2, 2024.
The concept described the development of a chiral acetal‐based stereo‐controlled degradable polymer, which was prepared via living cascade enyne metathesis polymerization with the controlled addition of highly stereodefined N,O‐acetal‐containing enyne monomers from Pd‐catalyzed asymmetric hydroamination of alkoxyallene and ring‐closing metathesis ...
Dayong Song, Bonwoo Koo, Houng Kang, Kyeongdeok Seo, Choeljae Kim   +4 more
wiley   +1 more source

Study on Toxic Substances in Astragalus adsurgens Infected with Alternaria gansuense

Agriculture
Yellow stunt and root rot causes premature degradation of Astragalus adsurgens grasslands in China. However, the etiological factors underlying livestock poisoning following the ingestion of diseased plants remain elusive.
Huaqi Liu, Yanzhong Li
doaj   +1 more source

Glycans in melanoma: Drivers of tumour progression but sweet targets to exploit for immunotherapy

Immunology, Volume 173, Issue 1, Page 33-52, September 2024.
Aberrant glycosylation patterns on tumour cells emerged as an unmissable hallmark of cancer progression. Such tumour ‘glycocode’ plays a major role in promoting tumour cell proliferation, invasion, migration, but also dismantles anti‐tumour defences through interactions with lectins expressed on immune cells.
Camille Niveau, Eleonora Sosa Cuevas, Philippe Saas, Caroline Aspord   +3 more
wiley   +1 more source

Synthesis of (−)-Swainsonine and (−)-8-epi-Swainsonine by the Addition of Allenylmetals to Chiral α,β-Alkoxy Sulfinylimines

, 2016
The asymmetric synthesis of (−)-swainsonine and (−)-8-epi-swainsonine is reported through the addition of either the allenylzinc or the allenyl lithio cyanocuprate reagents derived from [3-(methoxymethoxy)prop-1-ynyl]trimethylsilane to enantiopure α,β ...
Emmanuel Demont (1697854), Franck Ferreira (1649743), Fabrice Chemla (1649740), Alejandro Pérez-Luna (2007058), Julien Louvel (1664953)   +4 more
core   +1 more source

Investigation of the Protective Effect of Probiotic Lactobacillus plantarum Ep‐M17 on the Hepatopancreas of Penaeus vannamei

Aquaculture Nutrition, Volume 2024, Issue 1, 2024.
Infection with the pathogenic bacterium Vibrio parahaemolyticus typically causes severe hepatopancreatic damage in Penaeus vannamei, often resulting in acute shrimp mortality. Therefore, protecting the shrimp’s hepatopancreas is crucial for enhancing their disease resistance.
Xiaoman Hu, Wenlong Xu, Hao Li, Bowen Lu, Yang Du, Jiong Chen, Gouranga Biswas   +6 more
wiley   +1 more source