Results 31 to 40 of about 33,665 (238)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Swarm intelligence and its applications in swarm robotics [PDF]
, 2007 This work gives an overview of the broad field of computational swarm intelligence and its applications in swarm robotics. Computational swarm intelligence is modelled on the social behavior of animals and its principle application is as an optimization ...
Andina de la Fuente, Diego +1 more
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Evolution of Swarm Robotics Systems with Novelty Search
, 2013 Novelty search is a recent artificial evolution technique that challenges traditional evolutionary approaches. In novelty search, solutions are rewarded based on their novelty, rather than their quality with respect to a predefined objective. The lack of
Christensen, Anders Lyhne +2 more
core +1 more source
Robotic swarm control from spatio-temporal specifications [PDF]
, 2016 In this paper, we study the problem of controlling a two-dimensional robotic swarm with the purpose of achieving high level and complex spatio-temporal patterns.
Belta, Calin +2 more
core +2 more sources
Swarm Engineering Through Quantitative Measurement of Swarm Robotic Principles in a 10,000 Robot Swarm [PDF]
Proceedings of the Twenty-Eighth International Joint Conference on Artificial Intelligence, 2019 When designing swarm-robotic systems, system- atic comparison of algorithms from different do- mains is necessary to determine which is capa- ble of scaling up to handle the target problem size and target operating conditions. We propose a set of quantitative metrics for scalability, flexibility, and emergence which are capable of addressing these ...
Harwell, John, Gini, Maria
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A Decentralized Mobile Computing Network for Multi-Robot Systems Operations
, 2018 Collective animal behaviors are paradigmatic examples of fully decentralized operations involving complex collective computations such as collective turns in flocks of birds or collective harvesting by ants.
Bouffanais, Roland +2 more
core +1 more source
Fast moving of a population of robots through a complex scenario [PDF]
, 2019 Swarm robotics consists in using a large number of coordinated autonomous robots, or agents, to accomplish one or more tasks, using local and/or global rules. Individual and collective objectives can be designed for each robot of the swarm.
F Ginelli +5 more
core +1 more source