Results 41 to 50 of about 2,971,207 (141)

Identification of ZDHHC17 as a Potential Drug Target for Swine Acute Diarrhea Syndrome Coronavirus Infection. [PDF]

mBio, 2021
The recent emergence of deadly zoonotic viral diseases, including Ebola virus and SARS-CoV-2, emphasizes the importance of pandemic preparedness for the animal-sourced viruses with potential risk of animal-to-human spillover. Over the last 2 decades, three significant coronaviruses of bat origin, SARS-CoV, MERS-CoV, and SARS-CoV-2, have caused millions
Luo Y, Tan CW, Xie SZ, Chen Y, Yao YL, Zhao K, Zhu Y, Wang Q, Liu MQ, Yang XL, Wang LF, Shi ZL.   +11 more
europepmc   +5 more sources

Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus. [PDF]

Biosaf Health, 2021
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a recently discovered coronavirus that causes severe and acute diarrhea and rapid weight loss in piglets. SADS-CoV was reported to be capable of infecting cell lines derived from diverse species, including bats, mice, hamsters, rats, chickens, pigs, nonhuman primates, and humans, implying its high
Wang Q, Luo Y, Shang W, Shi Z, Xiao G, Zhang L.   +5 more
europepmc   +3 more sources

Analysis of Interaction Network Between Host Protein and M Protein of Swine Acute Diarrhea Syndrome Coronavirus. [PDF]

Front Microbiol, 2022
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an enterovirus that can cause acute diarrhea and death in piglets and cause serious economic losses to the pig industry. SADS-CoV membrane (M) protein mainly plays a key role in biological processes, such as virus assembly, budding, and host innate immune regulation.
Xu J, Cao Z, Ji C, Zhou L, Yan X, Sun Y, Ma J.   +6 more
europepmc   +4 more sources

Swine acute diarrhea syndrome coronavirus induces autophagy to promote its replication via the Akt/mTOR pathway. [PDF]

iScience, 2022
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an enveloped, single-stranded, positive-sense RNA virus belonging to the Coronaviridae family. Increasingly studies have demonstrated that viruses could utilize autophagy to promote their own replication. However, the relationship between SADS-CoV and autophagy remains unknown.
Zeng S, Zhao Y, Peng O, Xia Y, Xu Q, Li H, Xue C, Cao Y, Zhang H.   +8 more
europepmc   +4 more sources

Functional Dissection of the Spike Glycoprotein S1 Subunit and Identification of Cellular Cofactors for Regulation of Swine Acute Diarrhea Syndrome Coronavirus Entry [PDF]

Journal of Virology
Yao-Wei Huang, Yong-Le Yang, Berend Jan Bosch   +2 more
exaly   +2 more sources

Interplay between swine enteric coronaviruses and host innate immune

Frontiers in Veterinary Science, 2022
Swine enteric coronavirus (SeCoV) causes acute diarrhea, vomiting, dehydration, and high mortality in neonatal piglets, causing severe losses worldwide.
Mingwei Li, Longjun Guo, Li Feng
doaj   +1 more source

Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns

Veterinary Quarterly, 2022
Swine coronaviruses (SCoVs) are one of the most devastating pathogens affecting the livelihoods of farmers and swine industry across the world. These include transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine ...
Jigarji C. Thakor, Murali Dinesh, Rajendran Manikandan, Suresh Bindu, Monalisa Sahoo, Diptimayee Sahoo, Manish Dhawan, Megha Katare Pandey, Ruchi Tiwari, Talha Bin Emran, Kuldeep Dhama, Wanpen Chaicumpa   +11 more
doaj   +1 more source

Modulation of Innate Antiviral Immune Response by Porcine Enteric Coronavirus

Frontiers in Microbiology, 2022
Host’s innate immunity is the front-line defense against viral infections, but some viruses have evolved multiple strategies for evasion of antiviral innate immunity.
Kunli Zhang, Kunli Zhang, Sen Lin, Jianhao Li, Shoulong Deng, Jianfeng Zhang, Jianfeng Zhang, Sutian Wang   +7 more
doaj   +1 more source

Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids. [PDF]

PLoS Pathog, 2022
Intestinal microbial metabolites have been increasingly recognized as important regulators of enteric viral infection. However, very little information is available about which specific microbiota-derived metabolites are crucial for swine enteric coronavirus (SECoV) infection in vivo.
Yang QY, Yang YL, Tang YX, Qin P, Wang G, Xie JY, Chen SX, Ding C, Huang YW, Zhu SJ.   +9 more
europepmc   +4 more sources

Alphacoronaviruses Are Common in Bats in the Upper Midwestern United States

Viruses, 2022
Bats are a reservoir for coronaviruses (CoVs) that periodically spill over to humans, as evidenced by severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2. A collection of 174 bat samples originating from South Dakota, Minnesota, Iowa,
Reagan Schaeffer, Gun Temeeyasen, Ben M. Hause   +2 more
doaj   +1 more source