Results 21 to 30 of about 449,578 (382)
Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
core +1 more source
TH Open, 2019 Introduction Although physical exercise is protective against cardiovascular disease, it can also provoke sudden cardiac death (exercise paradox).
Cécile H. Kicken +6 more
doaj +1 more source
Electrochemistry at the Synapse [PDF]
Annual Review of Analytical Chemistry, 2019 Electrochemical measurements of neurotransmitters provide insight into the dynamics of neurotransmission. In this review, we describe the development of electrochemical measurements of neurotransmitters and how they started with extrasynaptic measurements but now are pushing toward synaptic measurements.
Jason R. Borgus +3 more
openaire +3 more sources
Frontiers in Psychiatry, 2021 COVID-19 Pandemic has influenced death-related attitudes and understanding during the childhood development leading to a life-long impact. Factors like pandemic-related movement restrictions, school closures, and parents' stay-at-home have exposed ...
Aisha Sanober Chachar +2 more
doaj +1 more source
Enhancement of synchronization in a hybrid neural circuit by spike timing dependent plasticity [PDF]
, 2003 Synchronization of neural activity is fundamental for many functions of the brain. We demonstrate that spike-timing dependent plasticity (STDP) enhances synchronization (entrainment) in a hybrid circuit composed of a spike generator, a dynamic clamp ...
Abarbanel, Henry D I +4 more
core +2 more sources
Robustness and Enhancement of Neural Synchronization by Activity-Dependent Coupling [PDF]
, 2002 We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP).
C. Bell +10 more
core +2 more sources
Autophagy at the synapse [PDF]
Neuroscience Letters, 2019 As the sites of communication between neurons, synapses depend upon precisely regulated protein-protein interactions to support neurotransmitter release and reception. Moreover, neuronal synapses typically exist great distances (i.e. up to meters) away from cell bodies, which are the sources of new proteins and the major sites of protein degradation ...
Clarissa L. Waites +2 more
openaire +3 more sources
The clinical promise of biomarkers of synapse damage or loss in Alzheimer’s disease
Alzheimer's Research & Therapy, 2020 Synapse damage and loss are fundamental to the pathophysiology of Alzheimer’s disease (AD) and lead to reduced cognitive function. The goal of this review is to address the challenges of forging new clinical development approaches for AD therapeutics ...
M. Colom‐Cadena +14 more
semanticscholar +1 more source
Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures [PDF]
, 2019 The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-aminobutyric acid type A receptors (GABAARs) at the appropriate synaptic sites.
Andrews, Peter M. +11 more
core +2 more sources
Frontiers in Neuroscience, 2022 Given the significance of validating reliable tests for the early detection of autism spectrum disorder (ASD), this systematic review aims to summarize available evidence of neuroimaging and neurophysiological changes in high-risk infants to improve ASD ...
Cullen Clairmont +7 more
doaj +1 more source