Results 21 to 30 of about 421,951 (351)
Probabilistic Fluorescence-Based Synapse Detection [PDF]
, 2016 Brain function results from communication between neurons connected by complex synaptic networks. Synapses are themselves highly complex and diverse signaling machines, containing protein products of hundreds of different genes, some in hundreds of ...
Aguerrebere, Cecilia +7 more
core +9 more sources
Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures [PDF]
, 2019 The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-aminobutyric acid type A receptors (GABAARs) at the appropriate synaptic sites.
Andrews, Peter M. +11 more
core +2 more sources
Frontiers in Psychiatry, 2021 COVID-19 Pandemic has influenced death-related attitudes and understanding during the childhood development leading to a life-long impact. Factors like pandemic-related movement restrictions, school closures, and parents' stay-at-home have exposed ...
Aisha Sanober Chachar +2 more
doaj +1 more source
Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation. [PDF]
, 2019 Memory and learning involve activity-driven expression of proteins and cytoskeletal reorganization at new synapses, requiring posttranscriptional regulation of localized mRNA a long distance from corresponding nuclei.
Davis, Ilan +6 more
core +4 more sources
Autophagy at the synapse [PDF]
Neuroscience Letters, 2019 As the sites of communication between neurons, synapses depend upon precisely regulated protein-protein interactions to support neurotransmitter release and reception. Moreover, neuronal synapses typically exist great distances (i.e. up to meters) away from cell bodies, which are the sources of new proteins and the major sites of protein degradation ...
Clarissa L. Waites +2 more
openaire +3 more sources
Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
Nature Communications, 2020 NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane.
Hongmei Shen +4 more
doaj +1 more source
Frontiers in Neuroscience, 2022 Given the significance of validating reliable tests for the early detection of autism spectrum disorder (ASD), this systematic review aims to summarize available evidence of neuroimaging and neurophysiological changes in high-risk infants to improve ASD ...
Cullen Clairmont +7 more
doaj +1 more source
Robustness and Enhancement of Neural Synchronization by Activity-Dependent Coupling [PDF]
, 2002 We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP).
C. Bell +10 more
core +2 more sources
Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review
TH Open, 2018 Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von ...
Lisa N. van der Vorm +3 more
doaj +1 more source
eLife, 2016 Synaptic vesicles in rodent neurons are recycled using at least two distinct mechanisms.
Henrique von Gersdorff, Owen P Gross
openaire +4 more sources