Results 31 to 40 of about 449,578 (382)
Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation. [PDF]
, 2019 Memory and learning involve activity-driven expression of proteins and cytoskeletal reorganization at new synapses, requiring posttranscriptional regulation of localized mRNA a long distance from corresponding nuclei.
Davis, Ilan +6 more
core +4 more sources
Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
Nature Communications, 2020 NMDA receptor-dependent long-term depression (NMDAR-LTD) is a form of synaptic plasticity mediated by reduced recycling of AMPA receptors to the plasma membrane.
Hongmei Shen +4 more
doaj +1 more source
Synapse elimination and learning rules co-regulated by MHC class I H2-Db. [PDF]
, 2014 The formation of precise connections between retina and lateral geniculate nucleus (LGN) involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the major histocompatibility complex (MHC)
Adelson, Jaimie +7 more
core +3 more sources
Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review
TH Open, 2018 Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von ...
Lisa N. van der Vorm +3 more
doaj +1 more source
eLife, 2020 In the cerebellar cortex, molecular layer interneurons use chemical and electrical synapses to form subnetworks that fine-tune the spiking output of the cerebellum.
Andreas Hoehne +2 more
doaj +1 more source
Frontiers in Immunology, 2022 Thrombosis is a major clinical complication of COVID-19 infection. COVID-19 patients show changes in coagulation factors that indicate an important role for the coagulation system in the pathogenesis of COVID-19.
Romy de Laat-Kremers +8 more
doaj +1 more source
IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α
Nature Communications, 2017 Molecular mechanisms regulating the development of inhibitory synapses are poorly understood. Here the authors show that IgSF21 interacts with neurexin2α to induce presynaptic differentiation of inhibitory synapses, and that mice lacking IgSF21 exhibit ...
Yuko Tanabe +6 more
doaj +1 more source
eLife, 2016 Synaptic vesicles in rodent neurons are recycled using at least two distinct mechanisms.
Henrique von Gersdorff, Owen P Gross
openaire +4 more sources
Thrombin generation in low plasma volumes
Thrombosis Journal, 2018 Accurate thrombin generation determination by calibrated automated thrombinography can be sustained when reducing the plasma and reagent volumes up to half, but not for higher reductions or plasma dilutions.
Saartje Bloemen +2 more
doaj +1 more source
Activity-dependent regulation of mitochondrial motility in developing cortical dendrites
eLife, 2021 Developing neurons form synapses at a high rate. Synaptic transmission is very energy-demanding and likely requires ATP production by mitochondria nearby.
Catia AP Silva +5 more
doaj +1 more source