Results 41 to 50 of about 326,472 (355)
Frontiers in Neurology, 2022 The IMI public-private partnership between the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA) was launched in 2008 with an initial budget of €2 billion.
Diana O'Rourke +9 more
doaj +1 more source
Astrocytic Ephrin-B1 Regulates Synapse Remodeling Following Traumatic Brain Injury. [PDF]
, 2016 Traumatic brain injury (TBI) can result in tissue alterations distant from the site of the initial injury, which can trigger pathological changes within hippocampal circuits and are thought to contribute to long-term cognitive and neuropsychological ...
Ethell, Iryna M +5 more
core +3 more sources
Learning with Chemical versus Electrical Synapses -- Does it Make a Difference? [PDF]
arXiv, 2023 Bio-inspired neural networks have the potential to advance our understanding of neural computation and improve the state-of-the-art of AI systems. Bio-electrical synapses directly transmit neural signals, by enabling fast current flow between neurons.
arxiv
Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
BMC Cancer, 2019 Following publication of the original article [1], the authors have re-evaluated the authorship for this article. The updated author group is:
Ho-Keun Kwon +10 more
doaj +1 more source
RNA, 2015 One reason we learn and remember is because synapses, the places where axons and dendrites meet, undergo experience-dependent changes whose long-lasting nature may underlie the formation and persistence of memory. Indeed, neurons use these morphological and biochemical alterations to distinguish experienced (i.e., stimulated) from naive (unstimulated ...
openaire +3 more sources
Identifiability of a Binomial Synapse [PDF]
Frontiers in Computational Neuroscience, 2020 Frontiers in Computational Neuroscience ...
Camille Gontier +2 more
openaire +5 more sources
Abacavir use is associated with increased prothrombin conversion
Frontiers in Immunology, 2023 There is ongoing debate as to whether abacavir (ABC) increases the risk for cardiovascular disease(CVD) in people living with HIV (PLHIV) and the mechanisms underlying this possible association.
Qiuting Yan +11 more
doaj +1 more source
Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß [PDF]
, 2017 Soluble amyloid-β (Aβ) oligomers, a key driver of pathogenesis in Alzheimer disease, bind to cellular prion proteins (PrPC) expressed on synaptosomes resulting in increased cholesterol concentrations, movement of cytoplasmic phospholipase A2 (cPLA2) to ...
Bate, C
core +2 more sources
Analytical and Bioanalytical Chemistry, 2006 Large-scale phosphoproteome analysis on synaptosome and preparation of post-synaptic density (PSD) were investigated. It was found that protein phosphor is a common event in the synapse, which is consistent with the presence of diverse classes of kinases and phosphatases in the synapse.
openaire +4 more sources
Platelet Activation Pathways Controlling Reversible Integrin αIIbβ3 Activation
TH OpenBackground Agonist-induced platelet activation, with the integrin αIIbβ3 conformational change, is required for fibrinogen binding. This is considered reversible under specific conditions, allowing a second phase of platelet aggregation.
Jinmi Zou +8 more
doaj +1 more source