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Synaptic vesicle life cycle and synaptic turnover
Journal of Physiology-Paris, 1993Cholinergic synaptic vesicles contain a mixture of soluble low molecular mass constituents. Besides acetylcholine these include Ca2+, ATP, GTP, small amounts of ADP and AMP, and also the diadenosine polyphosphates Ap4A and Ap5A. In synaptic vesicles isolated from the electric ray these diadenosine polyphosphates occur in mmol concentrations and might ...
H, Zimmermann +3 more
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Synaptic structural plasticity: Role of synaptic shape
Synapse, 1989AbstractRecent research has indicated that synaptic curvature is an important and potentially critical plastic feature of the synapse. Alterations in synaptic shape are related to synaptic function, being found both during maturation and in adulthood following neuronal activation.
E J, Markus, T L, Petit
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The concept of the engram refers to structural and/or physiological changes that underlie memory associations during learning. However, the precise biological basis of the engram remains elusive, with ongoing controversy regarding whether it resides at the cellular level or within the synaptic connections between activated cells.
Hyunsu, Jung +3 more
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Hyunsu, Jung +3 more
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Naturwissenschaften, 1979
Synaptic plasticity is manifested by long-lasting changes in synaptic potency. Increased potency is of special importance in relation to the neural basis of memory. Even mild repetitive stimulation evokes large and prolonged potentiations of hippocampal synapses, as is revealed by electrical recording either in vivo or in vitro.
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Synaptic plasticity is manifested by long-lasting changes in synaptic potency. Increased potency is of special importance in relation to the neural basis of memory. Even mild repetitive stimulation evokes large and prolonged potentiations of hippocampal synapses, as is revealed by electrical recording either in vivo or in vitro.
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Journal of Computational Neuroscience, 1999
We have developed compact analog integrated circuits that simulate two synaptic excitatory conductances. A four-transistor circuit captures the dynamics of an excitatory postsynaptic current caused by a real AMPA conductance. A six-transistor circuit simulates the effects of a real voltage-dependent NMDA conductance.
Rasche C, Douglas RJ
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We have developed compact analog integrated circuits that simulate two synaptic excitatory conductances. A four-transistor circuit captures the dynamics of an excitatory postsynaptic current caused by a real AMPA conductance. A six-transistor circuit simulates the effects of a real voltage-dependent NMDA conductance.
Rasche C, Douglas RJ
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Recording and Analyzing Synaptic Currents and Synaptic Potentials
Current Protocols in Neuroscience, 1999AbstractIntracellular recording of synaptic currents (PSCs) under voltage clamp conditions provides the most accurate and direct means for measuring the earliest effects of neurotransmitters. With this tool, combined with pharmacological or ionic manipulations, one can obtain information about the type of transmitter used at a synapse, the dynamics of ...
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1984
Synaptic vesicles are the characteristic organelles of the presynaptic nerve terminals of chemical synapses (i.e., those utilizing the release of a specific chemical transmitter substance to bring about synaptic transmission). They are normally 45–50 nm in diameter and must be among the most homogeneous and uniform lipoprotein membrane organelles known.
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Synaptic vesicles are the characteristic organelles of the presynaptic nerve terminals of chemical synapses (i.e., those utilizing the release of a specific chemical transmitter substance to bring about synaptic transmission). They are normally 45–50 nm in diameter and must be among the most homogeneous and uniform lipoprotein membrane organelles known.
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Projections in a Synaptic Algebra
Order, 2010zbMATH Open Web Interface contents unavailable due to conflicting licenses.
David J. Foulis, Sylvia Pulmannová
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Sleep and Synaptic Homeostasis
2014In the last decades a substantial knowledge about sleep mechanisms has been accumulated. However, the function of sleep still remains elusive. The difficulty with unraveling sleep's function may arise from the lack of understanding of how the multitude of processes associated with waking and sleep-from gene expression and single neuron activity to the ...
Vyazovskiy VV, FARAGUNA, UGO
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