Results 111 to 120 of about 2,578,136 (352)

Ferric Chelate Reductase 1 Like Protein (FRRS1L) Associates with Dynein Vesicles and Regulates Glutamatergic Synaptic Transmission

Frontiers in Molecular Neuroscience, 2017
In the brain, AMPA receptors (AMPARs)-mediated excitatory synaptic transmission is critically regulated by the receptor auxiliary subunits. Recent proteomic studies have identified that Ferric Chelate Reductase 1 Like protein (FRRS1L), whose mutations in
Wenyan Han, Huiqing Wang, Huiqing Wang, Huiqing Wang, Jun Li, Shizhong Zhang, Wei Lu   +6 more
doaj   +1 more source

Retraction Note to: Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors. [PDF]

BMC Neurosci, 2021
Wislet-Gendebien S, Visanji NP, Whitehead SN, Marsilio D, Hou W, Figeys D, Fraser PE, Bennett SAL, Tandon A.   +8 more
europepmc   +1 more source

Low‐Temperature Processed Optoelectronic Synapses With Enhanced Responsivity for Edge‐Oriented In‐Sensor Reservoir Computing

Advanced Materials Technologies, EarlyView.
Image pixels are converted into optical pulse sequences to stimulate the optoelectronic synaptic device, generating dynamic responses that form high‐dimensional features. These features improve classification efficiency and demonstrate strong potential for neuromorphic edge computing systems.
Jo‐Lin Chen, Shi‐Qian Guo, Yu‐Chuan Chiu, Po‐Tsun Liu   +3 more
wiley   +1 more source

Flexible Proton-Gated Oxide Synaptic Transistors on Si Membrane.

, 2016
Ion-conducting materials have received considerable attention for their applications in fuel cells, electrochemical devices, and sensors. Here, flexible indium zinc oxide (InZnO) synaptic transistors with multiple presynaptic inputs gated by proton ...
Liu, Yang Hui, Yang Hui Liu (2591713), Ji Chun Ye (2924634), Wan, Chang Jin, Xiao, Hui, Zhu, Li Qiang, Ping Qi Gao (2029444), Hui Xiao (185054), Wan, Qing, Gao, Ping Qi, Chang Jin Wan (2591710), Qing Wan (549049), Ye, Ji Chun, Li Qiang Zhu (2591707)   +13 more
core   +1 more source

Ultrafast Isolation of Synaptic Terminals From Rat Brain for Cryo-Electron Tomography Analysis

Bio-Protocol
Understanding the nanoscale organization and molecular rearrangement of synaptic components is critical for elucidating the mechanisms of synaptic transmission and plasticity.
Rong Sun, Qiangjun Zhou
doaj   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Manipulation of lipid rafts in neuronal cells

, 2010
Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core  

Lipids and synaptic functions

, 2018
International audienceSynaptic functions have long been thought to be driven by proteins, especially the SNARE complex, contrasting with a relatively passive role for lipids constituting cell membranes.
Mochel, Fanny, Fanny Mochel
core   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels

, 2013
Important modulatory roles have been attributed to presynaptic NMDA receptors (NMDARs) located on cerebellar interneuron terminals. Evidence supporting a presynaptic location includes an increase in the frequency of mini events following the application ...
Caldwell, M, Robertson, AD, Moss, GWJ, Benton, DCH, Smart, TG   +4 more
core